Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CSF1 4件: Ras signaling pathway, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Rheumatoid arthritis D06402 Sunitinib 2件: 28, 34
2 CSF1 4件: Ras signaling pathway, Viral protein interaction with cytokine and cytokine receptor, TNF signaling pathway, Rheumatoid arthritis D08552 Sunitinib 2件: 28, 34
3 CSF1R 3件: Ras signaling pathway, Viral protein interaction with cytokine and cytokine receptor, Transcriptional misregulation in cancer D11270 Pexidartinib 1件: 34
4 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D01977 Gefitinib 1件: 75
5 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D03455 Cetuximab 5件: 34, 51, 86, 89, 331
6 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04023 Erlotinib 1件: 94
7 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D04024 Lapatinib 3件: 34, 74, 75
8 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D07907 Erlotinib 1件: 94
9 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D08108 Lapatinib 3件: 34, 74, 75
10 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11251 Icotinib 1件: 34
11 EGFR 4件: Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis D11772 Tesevatinib 1件: 67
12 EPHA2 1件: Ras signaling pathway D03658 Dasatinib 2件: 51, 85
13 EPHA2 1件: Ras signaling pathway D06414 Dasatinib 2件: 51, 85
14 FGFR1 4件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
15 FGFR1 4件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
16 FGFR3 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
17 FGFR3 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
18 FGFR2 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D05338 Palifermin 5件: 13, 36, 38, 39, 65
19 FGFR2 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
20 FGFR2 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton D11589 Infigratinib 1件: 276
21 FLT1 3件: Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D03218 Axitinib 1件: 34
22 FLT1 3件: Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D06402 Sunitinib 2件: 28, 34
23 FLT1 3件: Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D08552 Sunitinib 2件: 28, 34
24 FLT1 3件: Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D08881 Cediranib 1件: 34
25 FLT1 3件: Ras signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis D10481 Nintedanib 5件: 51, 85, 89, 227, 228
26 FLT3 2件: Ras signaling pathway, Transcriptional misregulation in cancer D06272 Sorafenib 2件: 34, 86
27 FLT3 2件: Ras signaling pathway, Transcriptional misregulation in cancer D06402 Sunitinib 2件: 28, 34
28 FLT3 2件: Ras signaling pathway, Transcriptional misregulation in cancer D08524 Sorafenib 2件: 34, 86
29 FLT3 2件: Ras signaling pathway, Transcriptional misregulation in cancer D08552 Sunitinib 2件: 28, 34
30 FLT3 2件: Ras signaling pathway, Transcriptional misregulation in cancer D11270 Pexidartinib 1件: 34
31 FLT4 1件: Ras signaling pathway D03218 Axitinib 1件: 34
32 FLT4 1件: Ras signaling pathway D06272 Sorafenib 2件: 34, 86
33 FLT4 1件: Ras signaling pathway D06402 Sunitinib 2件: 28, 34
34 FLT4 1件: Ras signaling pathway D08524 Sorafenib 2件: 34, 86
35 FLT4 1件: Ras signaling pathway D08552 Sunitinib 2件: 28, 34
36 FLT4 1件: Ras signaling pathway D08881 Cediranib 1件: 34
37 FLT4 1件: Ras signaling pathway D10481 Nintedanib 5件: 51, 85, 89, 227, 228
38 FLT4 1件: Ras signaling pathway D11772 Tesevatinib 1件: 67
39 ABL1 2件: Ras signaling pathway, Viral myocarditis D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
40 ABL1 2件: Ras signaling pathway, Viral myocarditis D03252 Bosutinib 2件: 2, 67
41 ABL1 2件: Ras signaling pathway, Viral myocarditis D03658 Dasatinib 2件: 51, 85
42 ABL1 2件: Ras signaling pathway, Viral myocarditis D06414 Dasatinib 2件: 51, 85
43 ABL1 2件: Ras signaling pathway, Viral myocarditis D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
44 ABL1 2件: Ras signaling pathway, Viral myocarditis D08953 Nilotinib 5件: 6, 8, 34, 51, 86
45 ABL1 2件: Ras signaling pathway, Viral myocarditis D09664 Saracatinib 3件: 6, 89, 272
46 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
47 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
48 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D00777 Amantadine 4件: 6, 8, 13, 127
49 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
50 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D02780 Acamprosate 2件: 6, 206
51 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
52 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
53 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
54 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D07058 Acamprosate 2件: 6, 206
55 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D07283 Esketamine 3件: 2, 4, 70
56 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D07441 Amantadine 4件: 6, 8, 13, 127
57 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
58 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
59 GRIN1 2件: Ras signaling pathway, Spinocerebellar ataxia D09917 Latrepirdine 1件: 8
60 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
61 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
62 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00777 Amantadine 4件: 6, 8, 13, 127
63 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
64 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D02780 Acamprosate 2件: 6, 206
65 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
66 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
67 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
68 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
69 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
70 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
71 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
72 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
73 GRIN2A 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
74 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00711 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
75 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00775 Riluzole 9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
76 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00777 Amantadine 4件: 6, 8, 13, 127
77 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
78 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D02780 Acamprosate 2件: 6, 206
79 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
80 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
81 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D04905 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
82 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07058 Acamprosate 2件: 6, 206
83 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07283 Esketamine 3件: 2, 4, 70
84 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D07441 Amantadine 4件: 6, 8, 13, 127
85 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08098 Ketamine 8件: 2, 4, 6, 13, 70, 113, 156, 215
86 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D08174 Memantine 7件: 2, 6, 8, 13, 49, 127, 205
87 GRIN2B 3件: Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus D09917 Latrepirdine 1件: 8
88 IGF1R 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D03297 Mecasermin 6件: 65, 78, 96, 168, 265, 299
89 IGF1R 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D04870 Mecasermin 6件: 65, 78, 96, 168, 265, 299
90 IGF1R 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09680 Teprotumumab 1件: 51
91 IGF1R 3件: Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09925 Linsitinib 1件: 232
92 INSR 3件: Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D00085 Insulin human 2件: 96, 156
93 INSR 3件: Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03230 Insulin human 2件: 96, 156
94 INSR 3件: Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D03250 Insulin glargine 1件: 299
95 INSR 3件: Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus D04539 Insulin detemir 1件: 299
96 KDR 2件: Ras signaling pathway, VEGF signaling pathway D03218 Axitinib 1件: 34
97 KDR 2件: Ras signaling pathway, VEGF signaling pathway D06272 Sorafenib 2件: 34, 86
98 KDR 2件: Ras signaling pathway, VEGF signaling pathway D06402 Sunitinib 2件: 28, 34
99 KDR 2件: Ras signaling pathway, VEGF signaling pathway D08524 Sorafenib 2件: 34, 86
100 KDR 2件: Ras signaling pathway, VEGF signaling pathway D08552 Sunitinib 2件: 28, 34
101 KDR 2件: Ras signaling pathway, VEGF signaling pathway D08881 Cediranib 1件: 34
102 KDR 2件: Ras signaling pathway, VEGF signaling pathway D10062 Cabozantinib 1件: 34
103 KDR 2件: Ras signaling pathway, VEGF signaling pathway D10481 Nintedanib 5件: 51, 85, 89, 227, 228
104 KDR 2件: Ras signaling pathway, VEGF signaling pathway D11772 Tesevatinib 1件: 67
105 KIT 1件: Ras signaling pathway D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
106 KIT 1件: Ras signaling pathway D03658 Dasatinib 2件: 51, 85
107 KIT 1件: Ras signaling pathway D06272 Sorafenib 2件: 34, 86
108 KIT 1件: Ras signaling pathway D06402 Sunitinib 2件: 28, 34
109 KIT 1件: Ras signaling pathway D06414 Dasatinib 2件: 51, 85
110 KIT 1件: Ras signaling pathway D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
111 KIT 1件: Ras signaling pathway D08524 Sorafenib 2件: 34, 86
112 KIT 1件: Ras signaling pathway D08552 Sunitinib 2件: 28, 34
113 KIT 1件: Ras signaling pathway D08953 Nilotinib 5件: 6, 8, 34, 51, 86
114 KIT 1件: Ras signaling pathway D10229 Masitinib 6件: 2, 5, 6, 13, 46, 96
115 KIT 1件: Ras signaling pathway D11270 Pexidartinib 1件: 34
116 MET 3件: Ras signaling pathway, Transcriptional misregulation in cancer, Renal cell carcinoma D10062 Cabozantinib 1件: 34
117 NFKB1 17件: Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D01146 Iguratimod 4件: 46, 51, 53, 271
118 NGF 1件: Ras signaling pathway D09387 Tanezumab 2件: 226, 298
119 NGFR 2件: Ras signaling pathway, Transcriptional misregulation in cancer D11028 Cenegermin 2件: 53, 90
120 PDGFRA 2件: Ras signaling pathway, Regulation of actin cytoskeleton D01441 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
121 PDGFRA 2件: Ras signaling pathway, Regulation of actin cytoskeleton D06402 Sunitinib 2件: 28, 34
122 PDGFRA 2件: Ras signaling pathway, Regulation of actin cytoskeleton D08066 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
123 PDGFRA 2件: Ras signaling pathway, Regulation of actin cytoskeleton D08552 Sunitinib 2件: 28, 34
124 PDGFRA 2件: Ras signaling pathway, Regulation of actin cytoskeleton D08953 Nilotinib 5件: 6, 8, 34, 51, 86
125 PDGFRA 2件: Ras signaling pathway, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
126 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D03658 Dasatinib 2件: 51, 85
127 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D06272 Sorafenib 2件: 34, 86
128 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D06402 Sunitinib 2件: 28, 34
129 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D06414 Dasatinib 2件: 51, 85
130 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D08524 Sorafenib 2件: 34, 86
131 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D08552 Sunitinib 2件: 28, 34
132 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D08953 Nilotinib 5件: 6, 8, 34, 51, 86
133 PDGFRB 2件: Ras signaling pathway, Regulation of actin cytoskeleton D10481 Nintedanib 5件: 51, 85, 89, 227, 228
134 PGF 1件: Ras signaling pathway D09574 Aflibercept 2件: 90, 166
135 PIK3CA 19件: Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
136 PIK3CB 19件: Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
137 PIK3CD 19件: Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11158 Leniolisib 2件: 53, 65
138 PIK3CD 19件: Ras signaling pathway, Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Shigellosis, Salmonella infection, Yersinia infection, Viral carcinogenesis, Renal cell carcinoma, Small cell lung cancer D11437 Parsaclisib 3件: 35, 53, 61
139 MAP2K1 16件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
140 MAP2K1 16件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
141 MAP2K1 16件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
142 MAP2K1 16件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
143 MAP2K2 14件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D09666 Selumetinib 1件: 34
144 MAP2K2 14件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10175 Trametinib 4件: 2, 34, 279, 280
145 MAP2K2 14件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10405 Cobimetinib 1件: 280
146 MAP2K2 14件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Yersinia infection, Renal cell carcinoma, Thyroid cancer D10604 Binimetinib 1件: 34
147 RAF1 13件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D06272 Sorafenib 2件: 34, 86
148 RAF1 13件: Ras signaling pathway, Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Relaxin signaling pathway, Salmonella infection, Tuberculosis, Renal cell carcinoma D08524 Sorafenib 2件: 34, 86
149 RELA 17件: Ras signaling pathway, Sphingolipid signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Relaxin signaling pathway, Shigellosis, Salmonella infection, Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis, Small cell lung cancer D12181 Edasalonexent 1件: 113
150 VEGFA 5件: Ras signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D05697 Ranibizumab 4件: 34, 166, 227, 301
151 VEGFA 5件: Ras signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D06409 Bevacizumab 9件: 13, 34, 85, 86, 87, 89, 227, 280, 331
152 VEGFA 5件: Ras signaling pathway, VEGF signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis D09574 Aflibercept 2件: 90, 166
153 VEGFB 2件: Ras signaling pathway, Relaxin signaling pathway D09574 Aflibercept 2件: 90, 166
154 FGF23 2件: Ras signaling pathway, Regulation of actin cytoskeleton D10913 Burosumab 1件: 238