Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 Related to 17 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
2 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
3 | Adipocytokine signaling pathway 💬 Related to 16 target genes, 31 drugs (DrugBank) and 96 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
4 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
5 | African trypanosomiasis 💬 Related to 7 target genes, 19 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
6 | AGE-RAGE signaling pathway in diabetic complications 💬 Related to 25 target genes, 42 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
7 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
8 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
9 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
10 | Alcoholic liver disease 💬 Related to 39 target genes, 44 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
11 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
12 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
13 | Allograft rejection 💬 Related to 31 target genes, 24 drugs (DrugBank) and 58 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
14 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
15 | Alzheimer disease 💬 Related to 56 target genes, 117 drugs (DrugBank) and 121 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
16 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
17 | Amoebiasis 💬 Related to 18 target genes, 26 drugs (DrugBank) and 64 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
18 | Amphetamine addiction 💬 Related to 24 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
19 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
20 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
21 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
22 | AMPK signaling pathway 💬 Related to 16 target genes, 48 drugs (DrugBank) and 90 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
23 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
24 | Amyotrophic lateral sclerosis 💬 Related to 34 target genes, 46 drugs (DrugBank) and 106 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
25 | Antifolate resistance 💬 Related to 8 target genes, 21 drugs (DrugBank) and 67 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
26 | Antigen processing and presentation 💬 Related to 23 target genes, 15 drugs (DrugBank) and 54 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
27 | Apoptosis 💬 Related to 16 target genes, 26 drugs (DrugBank) and 59 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
28 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 44 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
29 | Asthma 💬 Related to 22 target genes, 23 drugs (DrugBank) and 57 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
30 | Autoimmune thyroid disease 💬 Related to 42 target genes, 16 drugs (DrugBank) and 37 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
31 | Axon guidance 💬 Related to 21 target genes, 21 drugs (DrugBank) and 69 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
32 | B cell receptor signaling pathway 💬 Related to 17 target genes, 22 drugs (DrugBank) and 66 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
33 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
34 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
35 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
36 | Bile secretion 💬 Related to 11 target genes, 29 drugs (DrugBank) and 60 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
37 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
38 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
39 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 62 drugs (DrugBank) and 98 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
40 | Calcium signaling pathway 💬 Related to 76 target genes, 190 drugs (DrugBank) and 138 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
41 | cAMP signaling pathway 💬 Related to 66 target genes, 169 drugs (DrugBank) and 117 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
42 | Cell adhesion molecules 💬 Related to 32 target genes, 21 drugs (DrugBank) and 37 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
43 | Cellular senescence 💬 Related to 32 target genes, 38 drugs (DrugBank) and 91 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
44 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
45 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
46 | Chagas disease 💬 Related to 27 target genes, 42 drugs (DrugBank) and 78 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
47 | Chemical carcinogenesis - receptor activation 💬 Related to 38 target genes, 123 drugs (DrugBank) and 117 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
48 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
49 | Coronavirus disease - COVID-19 💬 Related to 50 target genes, 88 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
50 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
51 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
52 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
53 | Cytokine-cytokine receptor interaction 💬 Related to 81 target genes, 110 drugs (DrugBank) and 99 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
54 | Diabetic cardiomyopathy 💬 Related to 22 target genes, 39 drugs (DrugBank) and 73 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
55 | Dilated cardiomyopathy 💬 Related to 17 target genes, 55 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
56 | Dopaminergic synapse 💬 Related to 30 target genes, 97 drugs (DrugBank) and 100 diseases in DDrare |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
57 | Epstein-Barr virus infection 💬 Related to 64 target genes, 58 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
58 | Estrogen signaling pathway 💬 Related to 19 target genes, 70 drugs (DrugBank) and 62 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
59 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
60 | Fc epsilon RI signaling pathway 💬 Related to 20 target genes, 38 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
61 | Fluid shear stress and atherosclerosis 💬 Related to 30 target genes, 47 drugs (DrugBank) and 85 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
62 | Gastric cancer 💬 Related to 21 target genes, 31 drugs (DrugBank) and 59 diseases in DDrare |
RARB 1件: RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
63 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
64 | Glucagon signaling pathway 💬 Related to 13 target genes, 20 drugs (DrugBank) and 83 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
65 | Glutamatergic synapse 💬 Related to 22 target genes, 26 drugs (DrugBank) and 82 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
66 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
67 | Graft-versus-host disease 💬 Related to 27 target genes, 22 drugs (DrugBank) and 62 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
68 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
69 | Hematopoietic cell lineage 💬 Related to 46 target genes, 70 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
70 | Hepatitis B 💬 Related to 40 target genes, 49 drugs (DrugBank) and 75 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
71 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
72 | Hepatitis C 💬 Related to 34 target genes, 55 drugs (DrugBank) and 75 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
73 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
74 | Herpes simplex virus 1 infection 💬 Related to 62 target genes, 61 drugs (DrugBank) and 97 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
75 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
76 | Human cytomegalovirus infection 💬 Related to 61 target genes, 99 drugs (DrugBank) and 121 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
77 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
78 | Human immunodeficiency virus 1 infection 💬 Related to 45 target genes, 41 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
79 | Human papillomavirus infection 💬 Related to 46 target genes, 88 drugs (DrugBank) and 108 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
80 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
81 | Human T-cell leukemia virus 1 infection 💬 Related to 56 target genes, 57 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
82 | Hypertrophic cardiomyopathy 💬 Related to 20 target genes, 50 drugs (DrugBank) and 89 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
83 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
84 | IL-17 signaling pathway 💬 Related to 20 target genes, 59 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
85 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
86 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
87 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
88 | Inflammatory bowel disease 💬 Related to 38 target genes, 43 drugs (DrugBank) and 67 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
89 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
90 | Influenza A 💬 Related to 58 target genes, 60 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
91 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
92 | Insulin resistance 💬 Related to 17 target genes, 30 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
93 | Intestinal immune network for IgA production 💬 Related to 30 target genes, 27 drugs (DrugBank) and 49 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
94 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
95 | JAK-STAT signaling pathway 💬 Related to 56 target genes, 87 drugs (DrugBank) and 106 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
96 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
97 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 56 target genes, 81 drugs (DrugBank) and 110 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
98 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
99 | Legionellosis 💬 Related to 9 target genes, 21 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
100 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
101 | Leishmaniasis 💬 Related to 38 target genes, 62 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
102 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
103 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
104 | Lipid and atherosclerosis 💬 Related to 46 target genes, 53 drugs (DrugBank) and 94 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
105 | Long-term potentiation 💬 Related to 17 target genes, 31 drugs (DrugBank) and 85 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
106 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
IL12A 1件: IL12A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
107 | Malaria 💬 Related to 14 target genes, 26 drugs (DrugBank) and 63 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
108 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
109 | MAPK signaling pathway 💬 Related to 60 target genes, 81 drugs (DrugBank) and 111 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
110 | Measles 💬 Related to 39 target genes, 41 drugs (DrugBank) and 52 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
111 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
112 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
113 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
114 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
115 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 136 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
116 | mTOR signaling pathway 💬 Related to 13 target genes, 29 drugs (DrugBank) and 90 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
117 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
118 | Natural killer cell mediated cytotoxicity 💬 Related to 41 target genes, 40 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
119 | Necroptosis 💬 Related to 28 target genes, 38 drugs (DrugBank) and 71 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
120 | NF-kappa B signaling pathway 💬 Related to 19 target genes, 64 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
121 | NOD-like receptor signaling pathway 💬 Related to 30 target genes, 40 drugs (DrugBank) and 68 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
122 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
123 | Non-alcoholic fatty liver disease 💬 Related to 23 target genes, 44 drugs (DrugBank) and 86 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
124 | Non-small cell lung cancer 💬 Related to 20 target genes, 29 drugs (DrugBank) and 45 diseases in DDrare |
RARB 1件: RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
125 | Oocyte meiosis 💬 Related to 14 target genes, 40 drugs (DrugBank) and 78 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
126 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
127 | Osteoclast differentiation 💬 Related to 36 target genes, 64 drugs (DrugBank) and 93 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
128 | Ovarian steroidogenesis 💬 Related to 6 target genes, 35 drugs (DrugBank) and 52 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
129 | Oxytocin signaling pathway 💬 Related to 33 target genes, 71 drugs (DrugBank) and 108 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
130 | Pathogenic Escherichia coli infection 💬 Related to 26 target genes, 38 drugs (DrugBank) and 74 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
131 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
132 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
133 | Pathways in cancer 💬 Related to 103 target genes, 188 drugs (DrugBank) and 137 diseases in DDrare |
RARA 2件: RARA, RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
134 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
135 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 122 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
136 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 Related to 32 target genes, 46 drugs (DrugBank) and 92 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
137 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
138 | Pertussis 💬 Related to 18 target genes, 36 drugs (DrugBank) and 67 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
139 | PI3K-Akt signaling pathway 💬 Related to 76 target genes, 112 drugs (DrugBank) and 119 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
140 | PPAR signaling pathway 💬 Related to 10 target genes, 13 drugs (DrugBank) and 31 diseases in DDrare |
PPARA 1件: PPARA 💬 |
D01366 D01366 💬 |
Bezafibrate | 020 7件: 20, 93, 94, 160, 296, 316, 324 💬 |
141 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
142 | Prion disease 💬 Related to 41 target genes, 63 drugs (DrugBank) and 106 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
143 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
IL12B 1件: IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
144 | Proteoglycans in cancer 💬 Related to 28 target genes, 64 drugs (DrugBank) and 98 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
145 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 109 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
146 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
147 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
148 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
149 | Rheumatoid arthritis 💬 Related to 37 target genes, 49 drugs (DrugBank) and 76 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
150 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
151 | RIG-I-like receptor signaling pathway 💬 Related to 22 target genes, 18 drugs (DrugBank) and 56 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
152 | Salmonella infection 💬 Related to 26 target genes, 36 drugs (DrugBank) and 66 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
153 | Serotonergic synapse 💬 Related to 37 target genes, 110 drugs (DrugBank) and 79 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
154 | Shigellosis 💬 Related to 23 target genes, 39 drugs (DrugBank) and 87 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
155 | Small cell lung cancer 💬 Related to 14 target genes, 38 drugs (DrugBank) and 58 diseases in DDrare |
RARB 1件: RARB 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
156 | Sphingolipid signaling pathway 💬 Related to 29 target genes, 48 drugs (DrugBank) and 73 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
157 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
158 | Systemic lupus erythematosus 💬 Related to 28 target genes, 38 drugs (DrugBank) and 79 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
159 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
160 | T cell receptor signaling pathway 💬 Related to 33 target genes, 44 drugs (DrugBank) and 80 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
161 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
162 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 18件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 299 💬 |
163 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00359 D00359 💬 |
Lovastatin | 006 11件: 6 , 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬 |
164 | Terpenoid backbone biosynthesis 💬 Related to 4 target genes, 13 drugs (DrugBank) and 52 diseases in DDrare |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
165 | TGF-beta signaling pathway 💬 Related to 11 target genes, 20 drugs (DrugBank) and 57 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
166 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
167 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
168 | Th1 and Th2 cell differentiation 💬 Related to 46 target genes, 37 drugs (DrugBank) and 72 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
169 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL17A 1件: IL17A 💬 |
D09967 D09967 💬 |
Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬 |
170 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL23A 1件: IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
171 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
IL4R 1件: IL4R 💬 |
D10354 D10354 💬 |
Dupilumab | 051 4件: 51, 98, 160, 162 💬 |
172 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
173 | Th17 cell differentiation 💬 Related to 56 target genes, 65 drugs (DrugBank) and 99 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
174 | TNF signaling pathway 💬 Related to 19 target genes, 54 drugs (DrugBank) and 83 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
175 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
176 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
177 | Toll-like receptor signaling pathway 💬 Related to 35 target genes, 42 drugs (DrugBank) and 65 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
178 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
ALOX5 1件: ALOX5 💬 |
D00414 D00414 💬 |
Zileuton | 085 3件: 85, 160, 164 💬 |
179 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
180 | Toxoplasmosis 💬 Related to 39 target genes, 39 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
181 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
182 | Transcriptional misregulation in cancer 💬 Related to 26 target genes, 47 drugs (DrugBank) and 77 diseases in DDrare |
RARA 1件: RARA 💬 |
D00348 D00348 💬 |
Isotretinoin | 036 4件: 36, 39, 159, 160 💬 |
183 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
184 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
185 | Tuberculosis 💬 Related to 62 target genes, 63 drugs (DrugBank) and 95 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
186 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
187 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
IL12A 2件: IL12A, IL12B 💬 |
D09214 D09214 💬 |
Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 |
188 | Type I diabetes mellitus 💬 Related to 31 target genes, 23 drugs (DrugBank) and 71 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
189 | Type II diabetes mellitus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 92 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
190 | VEGF signaling pathway 💬 Related to 20 target genes, 50 drugs (DrugBank) and 90 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
191 | Viral myocarditis 💬 Related to 30 target genes, 20 drugs (DrugBank) and 47 diseases in DDrare |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
192 | Viral protein interaction with cytokine and cytokine receptor 💬 Related to 18 target genes, 28 drugs (DrugBank) and 61 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |
193 | Wnt signaling pathway 💬 Related to 8 target genes, 8 drugs (DrugBank) and 60 diseases in DDrare |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D05480 D05480 💬 |
Pimecrolimus | 160 1件: 160 💬 |
194 | Yersinia infection 💬 Related to 21 target genes, 35 drugs (DrugBank) and 69 diseases in DDrare |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271 💬 |