Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Azithromycin
(Synonym: Azithromycin Monohydrate)		[5] AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX[3] D02134 ,
D06390 (Name: AZITHROMYCIN MONOHYDRATE),
D07486 		--[6] 13, 84, 85, 96, 228, 299
2 Caffeine [1] Caffeine[2] D00528 ,
D01453 (Name: Caffeine monohydrate)		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
3 Calcifediol [2] 25-Hydroxyvitamin D3; CALCIFEDIOL[1] D00122 (Name: Calcifediol monohydrate)[1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 113, 299
4 Cefadroxil [0] [2] D00257 ,
D02353 (Name: Cefadroxil monohydrate)		--[2] 222, 240
5 Cephalexin [2] CEFALEXIN; Cephalexin[2] D00263 ,
D00906 (Name: Cephalexin monohydrate)		--[1] 299
6 Cisapride [1] CISAPRIDE[2] D00274 ,
D02092 (Name: Cisapride monohydrate)		[3] HTR2A,
HTR3A,
HTR4 💬		[7] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 13
7 Citric acid [1] Citric acid[2] D00037 ,
D01222 (Name: Citric acid monohydrate)		--[2] 53, 291
8 Cytarabine [1] Cytarabine[3] D00168 ,
D03046 (Name: Fosteabine sodium monohydrate),
D03637 		--[7] 11, 13, 14, 25, 49, 60, 65
9 D-glucose
(Synonym: Dextrose Monohydrate)		[2] D-glucose; Glucose[1] D00009 --[3] 49, 86, 88
10 Doxycycline
(Synonym: Doxycycline Monohydrate)		[4] Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets[5] D00307 (Name: DOXYCYCLINE MONOHYDRATE),
D02129 ,
D03903 ,
D03904 ,
D07876 		--[16] 13, 23, 28, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299
11 Isoniazid [1] Isoniazid[3] D00346 ,
D01501 ,
D02002 (Name: Isoniazid sodium methanesulfonate monohydrate)		--[2] 65, 254
12 Lactose [1] Lactose[2] D00046 ,
D03226 (Name: Lactose monohydrate (NF))		--[6] 2, 6, 13, 97, 228, 310
13 Lapatinib [1] Lapatinib[2] D04024 (Name: Lapatinib ditosylate monohydrate),
D08108 		[2] EGFR,
ERBB2 💬		[50] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬[3] 34, 74, 75
14 Lidocaine
(Synonym: Lidocaine Hydrochloride Monohydrate)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[3] D00358 ,
D02086 ,
D08127 (Name: Lidocaine hydrochloride monohydrate)		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
15 Metoclopramide [1] METOCLOPRAMIDE[3] D00726 ,
D02213 (Name: Metoclopramide dihydrochloride monohydrate),
D05008 (Name: Metoclopramide monohydrochloride monohydrate)		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 51
16 Mometasone [1] Mometasone[3] D00690 ,
D03325 (Name: Mometasone furoate monohydrate),
D08227 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 162
17 Mometasone furoate
(Synonym: Mometasone Furoate Monohydrate)		[3] Mometasone; MOMETASONE FUROATE; Nasonex[1] D00690 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 98, 162
18 Nitrofurantoin
(Synonym: Nitrofurantoin monohydrate/macrocrystals)		[1] Nitrofurantoin[1] D00439 (Name: NITROFURANTOIN MONOHYDRATE MACROCRYSTALLINE)--[1] 13
19 Olanzapine [2] Olanzapine; Zyprexa[2] D00454 ,
D06623 (Name: Olanzapine pamoate monohydrate)		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8
20 Pramipexole [7] Mirapex; Mirapex ER; Mirapexin; Pramipexol; Pramipexole; PRAMIPEXOLE DIHYDROCHLORIDE; SIFROL[2] D00559 (Name: Pramipexole dihydrochloride monohydrate),
D05575 		[3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 20
21 Prednisone [3] PREDNISONA; PREDNISONE; RAYOS[1] D00473 (Name: Prednisone monohydrate)[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
22 Pyridoxal phosphate [0] [1] D00006 (Name: Pyridoxal phosphate monohydrate)--[1] 13
23 Theophylline [1] Theophylline[5] D00371 ,
D01712 ,
D02017 ,
D06103 (Name: Theophylline monohydrate),
D06104 		[19] ADORA1,
ADORA2A,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬		[24] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 236, 299