10. シャルコー・マリー・トゥース病 Charcot-Marie-Tooth disease Clinical trials / Disease details

臨床試験数 : 39 / 薬物数 : 44 - (DrugBank : 9) / 標的遺伝子数 : 11 - 標的パスウェイ数 : 15

7 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-jRCTs031190109	25/10/2019	03/10/2019	Ascorbic acid treatment for childhood Charcot-Marie-Tooth disease 1A	Ascorbic acid treatment for childhood Charcot-Marie-Tooth disease 1A - Ascorbic acid for CMT1A	Charcot-Marie-Tooth disease type 1A CMT1A;G600	ascorbic acid dayly intake	SHIOHAMA TADASHI	NULL	Recruiting	Not applicable	< 18age old	Both	12	Phase 2	Japan
2	JPRN-UMIN000036332	2019/06/15	28/03/2019	Ascorbic acid treatment for Charcot-Marie-Tooth disease type 1A	Ascorbic acid treatment for Charcot-Marie-Tooth disease type 1A - Ascorbic acid treatment for CMT1A	Charcot-Marie-Tooth diease type 1A	Ascorbic acid treatment: 20mg/kg/day, dayly	Chiba University	NULL	Pending	1years-old	Not applicable	Male and Female	10	Phase 1	Japan
3	NCT00484510 (ClinicalTrials.gov)	April 2007	8/6/2007	High Dose Ascorbic Acid Treatment of CMT1A	A Randomized, Placebo-controlled, Double Masked 120 Subject Futility Design Clinical Trial of Ascorbic Acid Treatment of Charcot Marie Tooth Disease Type 1A.	Charcot-Marie-Tooth Disease, Type Ia	Drug: Ascorbic acid (Vitamin C);Drug: placebo	Wayne State University	Muscular Dystrophy Association;Charcot-Marie-Tooth Association	Completed	13 Years	70 Years	Both	110	Phase 2/Phase 3	United States
4	NCT00271635 (ClinicalTrials.gov)	January 2006	3/1/2006	Ascorbic Acid Treatment in CMT1A Trial (AATIC)	Phase 2 Study of Ascorbic Acid Treatment in Charcot-Marie-Tooth Type 1A	Charcot-Marie-Tooth Disease;Hereditary Motor and Sensory Neuropathies	Drug: Placebo;Drug: ascorbic acid	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	NULL	Completed	12 Years	25 Years	Both	13	Phase 2	Netherlands
5	EUCTR2006-000032-27-IT (EUCTR)	19/10/2005	14/03/2006	MULTICENTRE RANDOMISED DOUBLE BLIND PLACEBO CONTROLLED TRIAL OF LONG-TERM ASCORBIC ACID TREATMENT IN CHARCOT-MARIE-TOOTH DISEASE TYPE 1A CMT-TRIAAL CMT-TRial Italian with Ascorbic Acid Long term - CMT-TRIAAL	MULTICENTRE RANDOMISED DOUBLE BLIND PLACEBO CONTROLLED TRIAL OF LONG-TERM ASCORBIC ACID TREATMENT IN CHARCOT-MARIE-TOOTH DISEASE TYPE 1A CMT-TRIAAL CMT-TRial Italian with Ascorbic Acid Long term - CMT-TRIAAL	Charcot-Marie-Tooth disease type 1A CMT1A MedDRA version: 6.1;Level: HLGT;Classification code 10034606	Trade Name: CEBION 500MG 20CPR MAST.ARAN INN or Proposed INN: ACIDO ASCORBICO DC.IT INN or Proposed INN: SODIO ASCORBATO DC.IT	ISTITUTO NEUROLOGICO CARLO BESTA	NULL	Not Recruiting			Female: yes Male: yes	202		Italy
6	JPRN-UMIN000001535	2005/04/01	01/01/2009	A multicenter, randomized open trial of ascorbic acid treatment in Charcot-Marie-Tooth disease type 1A		Charcot-Marie-Tooth disease 1A	Ascorbic acid (AA) treatment group (12 weeks oral AA (20mg/kg/day) no AA treatment group	New treatment strategies for intractable neuropathies based on its pathomechanism.The Research Grant 19A-5 for Nervous and Mental Disorders from the Ministry of Health, Labour and Welfare.	NULL	Complete: follow-up complete	15years-old	75years-old	Male and Female	60	Phase 1,2	Japan
7	EUCTR2004-004501-24-IT (EUCTR)	22/12/2004	13/02/2007	Multicentre, randomised, double blind, placebo controlled trial of ascorbic acid treatment in Charcot-Marie-Tooth Disease Type 1A CMT1A .	Multicentre, randomised, double blind, placebo controlled trial of ascorbic acid treatment in Charcot-Marie-Tooth Disease Type 1A CMT1A .	Charcot-Marie-Tooth Disease Type 1A CMT1A . MedDRA version: 6.1;Level: HLT;Classification code 10022031	Trade Name: CEBION 500*20CPR MAST 500MG Product Name: ACIDO ASCORBICO INN or Proposed INN: Ascorbic acid vit C	ISTITUTO NEUROLOGICO CARLO BESTA	NULL	Not Recruiting			Female: yes Male: yes	200		Italy

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