( DrugBank: - )
1 disease
告示番号 | 疾患名(ページ内リンク) | 臨床試験数 |
---|---|---|
118 | 脊髄髄膜瘤 | 10 |
118. 脊髄髄膜瘤
臨床試験数 : 10 / 薬物数 : 18 - (DrugBank : 7) / 標的遺伝子数 : 8 - 標的パスウェイ数 : 12
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NCT04652908 (ClinicalTrials.gov) | June 21, 2021 | 25/11/2020 | Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial | Phase 1/2a Trial of Placental Mesenchymal Stem Cells for Repair of Fetal Myelomeningocele | Myelomeningocele | Biological: Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix;Other: Untreated contemporaneous cohort | Diana Lee Farmer | California Institute for Regenerative Medicine (CIRM) | Recruiting | 19 Weeks | 25 Weeks | All | 55 | Phase 1/Phase 2 | United States |
2 | NCT04738539 (ClinicalTrials.gov) | March 2, 2021 | 1/2/2021 | Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies | Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic Studies | Myelomeningocele;Neurogenic Bladder;Tethered Cord Syndrome;Bladder, Neurogenic;Urologic Diseases;Neurologic Dysfunction | Drug: Contrast Enhanced Voiding Urosonography with Urodynamic Testing;Diagnostic Test: Urodynamic Testing | University of Virginia | NULL | Recruiting | N/A | 18 Years | All | 105 | United States | |
3 | NCT04027374 (ClinicalTrials.gov) | July 1, 2019 | 16/7/2019 | Stress-associated Epigenetic Alterations in Newborns After Fetal Surgery | Epigenetic Alterations in Stress Regulation Genes Among Newborns After Fetal Surgery for Myelomeningocele Repair: An Exploratory Study | Meningomyelocele | Procedure: Fetal surgery for MMC repair | University Children's Hospital, Zurich | University of Zurich;Psychiatric University Hospital, Zurich | Recruiting | N/A | 3 Months | All | 90 | Switzerland | |
4 | JPRN-UMIN000040088 | 2019/07/01 | 07/04/2020 | Safety Assessment Clinical Test of Fetal Surgery for Myelomeningocele | Safety Assessment Clinical Test of Fetal Surgery for Myelomeningocele - Safety Assessment Clinical Test of Fetal Surgery for Myelomeningocele | Myelomeningocele | MMC(Myelomeningocele) open fetal surgery | OSAKA UniversityDepartment of MedicineDivision of Obstetrics and Gynecology | NULL | Recruiting | 20years-old | Not applicable | Female | 15 | Not selected | Japan |
5 | NCT03936322 (ClinicalTrials.gov) | May 7, 2019 | 1/5/2019 | Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot Study | Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot Study | Spina Bifida;Myelomeningocele;Neural Tube Defects | Device: Minimally invasive fetoscopic repair of MMC | Mayo Clinic | NULL | Active, not recruiting | 18 Years | N/A | Female | 3 | N/A | United States |
6 | NCT04362592 (ClinicalTrials.gov) | November 2, 2018 | 24/3/2020 | In-Utero Endoscopic Correction of Spina Bifida | In-Utero Endoscopic Correction of Spina Bifida: Laparotomy or Percutaneous | Neural Tube Defects;Spina Bifida;Myelomeningocele | Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique;Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique | University of Southern California | NULL | Recruiting | 18 Years | 52 Years | Female | 33 | N/A | United States |
7 | NCT02390895 (ClinicalTrials.gov) | May 17, 2017 | 15/2/2015 | Prenatal Endoscopic Repair of Fetal Spina Bifida | Prenatal Endoscopic Repair of Fetal Spina Bifida | Myelomeningocele | Procedure: endoscopic repair of myelomeningocele before 26 SA | Assistance Publique - Hôpitaux de Paris | NULL | Active, not recruiting | 18 Years | N/A | Female | 7 | N/A | France |
8 | NCT04468568 (ClinicalTrials.gov) | January 8, 2017 | 1/3/2020 | In Utero Repair of Myelomeningocele: Atosiban Versus Terbutaline | Assessment of Maternal Blood Gas Changes When Using Atosiban and Terbutaline as Tocolytic Agents, During in Utero Repair of Myelomeningocele | Myelomeningocele;Terbutaline Adverse Reaction;Pregnancy; Malformation Central Nervous System | Drug: Atosiban;Drug: Terbutaline | University of Sao Paulo General Hospital | NULL | Recruiting | 18 Years | 40 Years | Female | 28 | N/A | Brazil |
9 | NCT04186338 (ClinicalTrials.gov) | December 1, 2016 | 2/12/2019 | Daily Physical Activity in Myelomeningocele | Daily Physical Activity in Children and Adolescents With Low Lumbar and Sacral Level Myelomeningocele | Physical Activity | Device: Omnidirectional accelerometer monitor (3x3 cm and 16 g, Actical®, Philips Respironics) | Marmara University | NULL | Completed | 6 Years | 16 Years | All | 20 | NULL | |
10 | NCT00175123 (ClinicalTrials.gov) | May 2005 | 9/9/2005 | Effect of Botulinum Toxin in Neurogenic Bladders in Children With Myelomeningocele | Phase 4 Study of the Effect of Botulinum-A Toxin Injected in Neurogenic Overactive Bladders of Children Born With Myelomeningocele | Myelomeningocele;Bladder, Neurogenic | Drug: Botulinum A toxin | University of Aarhus | Aarhus University Hospital | Active, not recruiting | 2 Years | 16 Years | Both | 30 | Phase 4 | Denmark |