Gentamicin ( DrugBank: Gentamicin )

3 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
36	表皮水疱症	7
113	筋ジストロフィー	2
299	嚢胞性線維症	1

36. 表皮水疱症

臨床試験数 : 160 / 薬物数 : 195 - (DrugBank : 47) / 標的遺伝子数 : 50 - 標的パスウェイ数 : 124

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04644627 (ClinicalTrials.gov)	December 1, 2020	20/11/2020	Topical Gentamicin Nonsense Suppression Therapy of EB	TOPICAL GENTAMICIN TREATMENT OF PATIENTS WITH EPIDERMOLYSIS BULLOSA DUE TO NONSENSE MUTATIONS	Epidermolysis Bullosa	Drug: Gentamicin Sulfate	Oslo University Hospital	NULL	Recruiting	N/A	N/A	All	6	Phase 1/Phase 2	Norway
2	EUCTR2020-002337-15-NO (EUCTR)	16/09/2020	29/06/2020	TOPICAL GENTAMICIN TREATMENT OF PATIENTS WITH EPIDERMOLYSIS BULLOSA	TOPICAL GENTAMICINTREATMENT OF PATIENTS WITH EPIDERMOLYSIS BULLOSA DUE TO NONSENSE MUTATIONS (THE GE ...	Epidermolysis bullosa caused by nonsense mutations or splice site mutations;Therapeutic area: Diseas ...	Trade Name: Infectogenta Product Name: Gentamicin sulfate 0.1% ointment	Oslo University Hospital	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	6	Phase 2	Norway
3	NCT04140786 (ClinicalTrials.gov)	October 31, 2019	23/10/2019	Optimizing IV Gentamicin in JEB	Optimization of Intravenous GentamicinTreatment to Restore Functional Laminin 332 in JEB Patients Wi ...	Junctional Epidermolysis Bullosa	Drug: Gentamicin Sulfate, Injectable	University of Southern California	NULL	Recruiting	N/A	N/A	All	6	Phase 1/Phase 2	United States
4	NCT03392909 (ClinicalTrials.gov)	July 5, 2018	2/1/2018	Intravenous Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB)	Restoration of Full-Length Type VII Collagen in RDEB Patients With Nonsense Mutations After Intraven ...	Recessive Dystrophic Epidermolysis Bullosa	Drug: Gentamicin	University of Southern California	NULL	Recruiting	7 Years	N/A	All	9	Phase 1/Phase 2	United States
5	NCT03526159 (ClinicalTrials.gov)	June 1, 2018	17/4/2018	Gentamicin for Junctional Epidermolysis Bullosa	A Pilot Study of the Restoration of Functional Laminin 332 in JEB Patients With Nonsense Mutations A ...	Junctional Epidermolysis Bullosa	Drug: Gentamicin Sulfate	University of Southern California	NULL	Recruiting	N/A	N/A	All	6	Phase 1/Phase 2	United States
6	NCT03012191 (ClinicalTrials.gov)	February 2, 2017	4/1/2017	Gentamicin for RDEB	Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa Patients With Nonsense Mutations	Recessive Dystrophic Epidermolysis Bullosa	Drug: Gentamicin Sulfate	University of Southern California	NULL	Completed	N/A	N/A	All	6	Phase 1/Phase 2	United States
7	NCT02698735 (ClinicalTrials.gov)	February 25, 2016	19/2/2016	Gentamicin Therapy for Recessive Dystrophic Epidermolysis Bullosa (RDEB) Nonsense Mutation Patients		Recessive Dystrophic Epidermolysis Bullosa	Drug: Gentamicin;Drug: Placebo	University of Southern California	NULL	Completed	N/A	N/A	All	5	Phase 1/Phase 2	NULL

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113. 筋ジストロフィー

臨床試験数 : 622 / 薬物数 : 485 - (DrugBank : 99) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 168

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00451074 (ClinicalTrials.gov)	March 2007	21/3/2007	Six Month Study of Gentamicin in Duchenne Muscular Dystrophy With Stop Codons	A Six Month Randomized, Clinical Trial of Gentamicinin Duchenne Muscular Dystrophy Subjects With Sto ...	Duchenne Muscular Dystrophy	Drug: Gentamicin infusions twice a week for six months	Nationwide Children's Hospital	National Institutes of Health (NIH);National Institute of Neurological Disorders and Stroke (NINDS)	Completed	5 Years	20 Years	Male	12	Phase 1	United States
2	NCT00005574 (ClinicalTrials.gov)	February 2000	2/5/2000	Gentamicin Treatment of Muscular Dystrophy	Gentamicin Treatment of Patients With Muscular Dystrophy Due to Nonsense Mutations in Dystrophin	Becker Muscular Dystrophy;Duchenne Muscular Dystrophy	Drug: Gentamicin	National Institute of Neurological Disorders and Stroke (NINDS)	NULL	Completed	N/A	N/A	Both	4	Phase 1	United States

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299. 嚢胞性線維症

臨床試験数 : 1,696 / 薬物数 : 1,644 - (DrugBank : 272) / 標的遺伝子数 : 96 - 標的パスウェイ数 : 170

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00376428 (ClinicalTrials.gov)	January 2003	13/9/2006	Interest of Gentamicin-induced Readthrough in Cystic Fibrosis Patients	Application of Functional Electrophysiological Tests to Evaluate Pharmacological Treatments in Patie ...	Cystic Fibrosis	Drug: Gentamicin	Assistance Publique - Hôpitaux de Paris	NULL	Terminated	N/A	N/A	Both	20	Phase 2	France

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