Niacinamide ( DrugBank: Niacinamide )

4 diseases

5. 進行性核上性麻痺

臨床試験数 : 95 / 薬物数 : 119 - (DrugBank : 40) / 標的遺伝子数 : 65 - 標的パスウェイ数 : 108

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00605930 (ClinicalTrials.gov)	April 2004	14/1/2008	A Pilot Clinical Trial of Pyruvate, Creatine, and Niacinamide in Progressive Supranuclear Palsy.	Energy Metabolism in Neurodegenerative Diseases: A Randomized, Double Blind, Placebo-Controlled Clinical Pilot Trial of Pyruvate, Creatine, and Niacinamide in Progressive Supranuclear Palsy.	Progressive Supranuclear Palsy	Dietary Supplement: Pyruvate, creatine, niacinamide;Dietary Supplement: Placebo	University of Louisville	NULL	Completed	N/A	N/A	All	20	N/A	United States

臨床試験数 : 2,298 / 薬物数 : 2,202 - (DrugBank : 350) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 202

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03808961 (ClinicalTrials.gov)	January 1, 2020	16/1/2019	Niacin for Parkinsons Disease	NAPS: Niacin for Parkinsons Disease	Parkinson's Disease	Dietary Supplement: Niacin;Dietary Supplement: Niacinamide;Other: Placebo	VA Office of Research and Development	NULL	Recruiting	35 Years	N/A	All	100	N/A	United States

臨床試験数 : 3,342 / 薬物数 : 2,355 - (DrugBank : 406) / 標的遺伝子数 : 269 - 標的パスウェイ数 : 241

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01381354 (ClinicalTrials.gov)	October 2010	26/5/2011	Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)	Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)	Multiple Sclerosis	Other: Progressive exercise;Device: Neuromuscular electrical stimulation delivered using the electrical therapy device EMPI 300 PV;Other: Modified paleolithic diet;Dietary Supplement: Omega 3 fatty acids;Dietary Supplement: Full Spectrum vitamin;Dietary Supplement: Essential - hydroxytyrosol;Dietary Supplement: Maltodextrin fiber supplement;Dietary Supplement: Mineral boost (magnesium);Dietary Supplement: Niacinamide;Dietary Supplement: Methyl B12;Dietary Supplement: Taurine;Dietary Supplement: creatine;Dietary Supplement: thiamine;Dietary Supplement: riboflavin;Dietary Supplement: N acetylcysteine;Dietary Supplement: alpha lipoic acid;Dietary Supplement: L acetyl carnitine;Dietary Supplement: methyl folate;Dietary Supplement: coenzyme Q;Behavioral: meditation;Behavioral: self massage;Behavioral: learning;Dietary Supplement: Coconut oil	University of Iowa	Direct MS Canada;DJO Incorporated;Pinnaclife Inc.;TZ Press, LLC	Completed	18 Years	65 Years	All	38	Phase 1	United States

臨床試験数 : 216 / 薬物数 : 219 - (DrugBank : 50) / 標的遺伝子数 : 39 - 標的パスウェイ数 : 151

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02558595 (ClinicalTrials.gov)	September 22, 2015	21/9/2015	Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2)	Randomized, Controlled Pilot Study of Niacinamide in Polycystic Kidney Disease	Polycystic Kidney Disease	Dietary Supplement: Niacinamide;Other: Placebo	University of Kansas Medical Center	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Completed	18 Years	60 Years	All	36	Phase 2	United States
2	NCT02140814 (ClinicalTrials.gov)	May 2014	14/5/2014	Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease	Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease	Polycystic Kidney Disease	Dietary Supplement: Niacinamide	Alan Yu, MB, BChir	NULL	Completed	18 Years	50 Years	Both	10	Phase 2	United States