Dimebon (latrepirdine) ( DrugBank: Latrepirdine, Dimebon )

1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
8	ハンチントン病	10

8. ハンチントン病

臨床試験数 : 229 / 薬物数 : 193 - (DrugBank : 60) / 標的遺伝子数 : 84 - 標的パスウェイ数 : 158

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2009-018123-32-SE (EUCTR)	30/09/2010	10/06/2010	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's c ...	Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descript ...	Medivation, Inc	NULL	Not Recruiting			Female: yes Male: yes	350		United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden
2	EUCTR2009-018123-32-NL (EUCTR)	23/08/2010	14/04/2010	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's c ...	Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descript ...	Medivation, Inc	NULL	Not Recruiting			Female: yes Male: yes	350		United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden
3	EUCTR2009-018123-32-IT (EUCTR)	28/07/2010	15/07/2010	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	Huntington`s Corea MedDRA version: 9.1;Level: LLT;Classification code 10020469	Product Name: Dimebon INN or Proposed INN: Dimebon dihydrochloride Product Name: Dimebon INN or Propose ...	MEDIVATION, INC.	NULL	Not Recruiting			Female: yes Male: yes	350		United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden
4	EUCTR2009-018123-32-DE (EUCTR)	07/06/2010	02/03/2010	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's c ...	Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descript ...	Medivation, Inc	NULL	Not Recruiting			Female: yes Male: yes	350		Denmark;Netherlands;Germany;Italy;United Kingdom;Sweden
5	EUCTR2009-018123-32-GB (EUCTR)	14/05/2010	18/03/2010	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's c ...	Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descript ...	Medivation, Inc	NULL	Not Recruiting			Female: yes Male: yes	350		Germany;United Kingdom;Netherlands;Denmark;Italy;Sweden
6	EUCTR2009-018123-32-DK (EUCTR)	23/04/2010	16/03/2010	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	Huntington disease MedDRA version: 12.1;Level: LLT;Classification code 10020469;Term: Huntington's c ...	Product Name: Dimebon Product Code: Dimebon INN or Proposed INN: Dimebon dihydrochloride Other descript ...	Medivation, Inc	NULL	Not Recruiting			Female: yes Male: yes	350		United Kingdom;Germany;Netherlands;Denmark;Italy;Sweden
7	NCT01085266 (ClinicalTrials.gov)	February 2010	10/3/2010	An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine)in Subjects With ...	HORIZON-Plus: An Open-Label Extension of the HORIZON Protocol (DIM20) Evaluating the Safety of Dimeb ...	Huntington Disease	Drug: Dimebon (latrepirdine)	Medivation, Inc.	Pfizer;Pfizer	Terminated	30 Years	N/A	Both	362	Phase 3	NULL
8	NCT00990613 (ClinicalTrials.gov)	October 2009	6/10/2009	A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Sk ...	A Phase 1, Fixed Sequence, Cross-Over Study To Investigate The Single Dose Pharmacokinetics Of A Dim ...	Alzheimer's Disease;Huntington's Disease	Drug: Dimebon IR;Drug: Dimebon Transdermal	Pfizer	Medivation, Inc.	Completed	50 Years	85 Years	Both	19	Phase 1	United States
9	NCT00988624 (ClinicalTrials.gov)	October 2009	1/10/2009	A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations ...	A Phase 1, Randomized, Open-Label, Single Dose Cross-Over Study In Healthy Volunteers To Estimate Th ...	Alzheimer's Disease;Huntington Disease	Drug: Dimebon IR Tablet;Drug: Dimebon MR1;Drug: Dimebon MR2;Drug: Dimebon MR3;Drug: Dimebon MR4	Pfizer	Medivation, Inc.	Completed	18 Years	55 Years	Both	20	Phase 1	United States
10	NCT00975481 (ClinicalTrials.gov)	October 2009	10/9/2009	A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine)In Healthy Rec ...	A Randomized, Double-Blind, Placebo- And Active-Controlled Single-Dose, Crossover Study To Evaluate ...	Alzheimer's Disease;Huntington's Disease	Drug: dimebon;Drug: placebo;Drug: alprazolam	Pfizer	Medivation, Inc.	Completed	18 Years	55 Years	All	36	Phase 1	Canada

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