MK-4836 ( DrugBank: - )


1 disease
告示番号疾患名(ページ内リンク)臨床試験数
86肺動脈性肺高血圧症1

86. 肺動脈性肺高血圧症


臨床試験数 : 1,181 薬物数 : 701 - (DrugBank : 126) / 標的遺伝子数 : 105 - 標的パスウェイ数 : 192
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
1EUCTR2021-001633-40-DE
(EUCTR)
07/03/202206/12/2021Clinical trial investigating the effect of riociguat among patients with slightly elevated blood pressure in lung vesselsEfficacy and safety of riociguat (MK-4836) in incipient pulmonary vascular disease as an indicator for early pulmonary arterial Hypertension Doubleblind, randomized, multicentre, multinational, placebo-controlled phase IIastudyESRA - ESRA early pulmonary vascular disease, defined as either a) mean pulmonary arterial pressure (mPAP) =25 mmHg with pulmonary vascular resistance (PVR) =2 to <3 WU and pulmonary arterial wedge pressure (PAWP) =15 mmHg or b) mPAP 21-<25 mmHg with PVR =2 WU, and PAWP =15 mmHg associated with connective tissue disease (CTD) or as idiopathic/heritable form.
MedDRA version: 20.0;Level: HLT;Classification code 10037455;Term: Pulmonary vascular disorders NEC;System Organ Class: 100000004866;Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Product Name: Riociguat
Product Code: MK-4836
INN or Proposed INN: RIOCIGUAT
Other descriptive name: BAY 63-2521
Product Name: Riociguat
Product Code: MK-4836
INN or Proposed INN: RIOCIGUAT
Other descriptive name: BAY 63-2521
Product Name: Riociguat
Product Code: MK-4836
INN or Proposed INN: RIOCIGUAT
Other descriptive name: BAY 63-2521
Product Name: Riociguat
Product Code: MK-4836
INN or Proposed INN: RIOCIGUAT
Other descriptive name: BAY 63-2521
Product Name: Riociguat
Product Code: MK-4836
INN or Proposed INN: RIOCIGUAT
Other descriptive name: BAY 63-2521
Thoraxklinik Heidelberg gGmbHNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
70Phase 2France;Austria;Norway;Germany;United Kingdom;Switzerland;Italy