329. 無虹彩症
[臨床試験数:3,薬物数:2(DrugBank:2),標的遺伝子数:0,標的パスウェイ数:0]
Searched query = "Aniridia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT04117880 (ClinicalTrials.gov) | December 31, 2018 | 19/9/2019 | A Phase 2 Open Label Extension Study in Participants With Nonsense Mutation Aniridia | Nonsense Mutation Aniridia: An Ataluren (PTC124) Phase 2 Extension Study | Aniridia | Drug: Ataluren | PTC Therapeutics | NULL | Withdrawn | 2 Years | N/A | All | 0 | Phase 2 | NULL |
2 | NCT02647359 (ClinicalTrials.gov) | January 31, 2016 | 29/12/2015 | Study of Ataluren in Participants With Nonsense Mutation Aniridia | STAR: A Phase 2, Multicenter, Randomized, Double-Masked, Placebo-Controlled Study of the Safety and Efficacy of Ataluren (PTC124) for the Treatment of Nonsense Mutation Aniridia | Aniridia | Drug: Ataluren;Drug: Placebo | PTC Therapeutics | NULL | Active, not recruiting | 2 Years | N/A | All | 39 | Phase 2 | United States;Canada |
3 | JPRN-UMIN000002948 | 2013/04/01 | 29/12/2009 | Cultivated epithelial sheet transplantation for corneal epithelial stem cell deficiency | a) Steven's Johnson Syndromeb) Ocular cicatricial pemphigoidc) Chemical/ Thermal Burns of the Cornead) Gelatinous Drop Like Dystrophye) Salzmann Corneal Degenerationf) Congenital Aniridia | Corneal epithelial sheet transplantation Cultivated eptihealial sheet transplantation will be perfored in the surgical department of Keio University Hospital. Simultaneous lamellar keratoplasty will be allowed. Surgical procedure involves removal of all pannus and abnormal epithelial tissue, the use of 0.04% mitomycin C to prevent fibrosis, and transplantation of the cultivated sheet. | Department of Ophthalmology, Keio University School of Medicine | NULL | Complete: follow-up complete | 20years-old | Not applicable | Male and Female | 5 | Not selected | Japan |