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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acetate1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
2ADVATE1件: Antihemophilic factor, human recombinant---1件: 288 💬
3ADVATE (rAHF - PFM)1件: Antihemophilic factor, human recombinant---1件: 288 💬
4ADVATE (rAHF-PFM)1件: Antihemophilic factor, human recombinant---1件: 288 💬
5ADVATE 1000 IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant---1件: 288 💬
6ADVATE 1000IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant---1件: 288 💬
7ADVATE 500 IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant---1件: 288 💬
8Alphanate3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
9Alphanate 1000 I.U.3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
10Alphanate 1500 I.U.3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
11Alphanate SD/HT2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
12ALPHANATE*INF 1F 1000UI+F 10ML2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
13ALPHANATE*INF 1F 1500UI+F 10ML2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
14ALPHANATE*INF 1F 250UI+F 5ML2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
15ALPHANATE*INF 1F 500UI+F 5ML2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
16Antihemophilic Factor (Recombinant)----1件: 288 💬
17APCC, aPCC + TXA----1件: 288 💬
18ARC 1779----2件: 64, 288 💬
19ARC1779----2件: 64, 288 💬
20ARC1779 Injection----2件: 64, 288 💬
21BAX 111----1件: 288 💬
22BAX111----1件: 288 💬
23Biostate----1件: 288 💬
24Biostate®----1件: 288 💬
25BIVV001 (rFVIIIFc-VWF-XTEN)----1件: 288 💬
26Blood coagulation Factor VIII and vWF, human1件: Beroctocog alfa---1件: 288 💬
27Blood sample----20件: 8, 13, 46, 49, 51, 53, 61, 66, 84, 88, 96, 97, 107, 127, 235, 274, 280, 288, 294, 299 💬
28BORTEZOMIB2件: Bortezomib,
Bortezomib D-mannitol		1件: Bortezomib 💬1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
29Catridecacog1件: Catridecacog1件: Catridecacog 💬--2件: 97, 288 💬
30Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338 💬
31Cluvot----1件: 288 💬
32Coagadex1件: Coagulation factor X human---1件: 288 💬
33Coagulación factor VIII1件: Beroctocog alfa---1件: 288 💬
34Coagulation factor VIII1件: Beroctocog alfa---1件: 288 💬
35Coagulation factor X1件: Coagulation factor X human---1件: 288 💬
36Coagulation factor XIII1件: Factor XIII (human)---1件: 288 💬
37CoFactor----2件: 265, 288 💬
38Cyclophosphamide1件: Cyclophosphamide2件: Cyclophosphamide ,
Cyclophosphamide 💬		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
39DDAVP1件: Desmopressin1件: Desmopressin 💬2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 75, 288 💬
40DDAVP (Desmopressin)1件: Desmopressin1件: Desmopressin 💬2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬1件: 288 💬
41Desmopressin1件: Desmopressin1件: Desmopressin 💬2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬5件: 6, 64, 72, 225, 288 💬
42Desmopressin acetate2件: Acetate,
Desmopressin		1件: Desmopressin 💬2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288 💬
43Desmopressine1件: Desmopressin1件: Desmopressin 💬2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 225, 288 💬
44Efanesoctocog alfa1件: Efanesoctocog alfa1件: Efanesoctocog alfa 💬--1件: 288 💬
45Emicizumab1件: Emicizumab1件: Emicizumab 💬2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288 💬
46Emicizumab (ACE910, RO5534262)1件: Emicizumab1件: Emicizumab 💬2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288 💬
47Emicizumab Injection1件: Emicizumab1件: Emicizumab 💬2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288 💬
48Eqwilate----1件: 288 💬
49F13CD----1件: 288 💬
50F8VR----1件: 288 💬
51FACTANE 200 IU/ml----1件: 288 💬
52Factor VIII1件: Beroctocog alfa---1件: 288 💬
53Factor VIII concentrate1件: Beroctocog alfa---1件: 288 💬
54Factor von Willebrand1件: Von Willebrand factor human---1件: 288 💬
55FACTOR X1件: Coagulation factor X human---1件: 288 💬
56Factor XIII1件: Factor XIII (human)---3件: 51, 97, 288 💬
57Factor XIII Concentrate (Human)1件: Factor XIII (human)---1件: 288 💬
58Factor XIII Concentrate (Human), Pasteurized1件: Factor XIII (human)---1件: 288 💬
59Fanhdi----1件: 288 💬
60FANHDI 100 UI----1件: 288 💬
61Fanhdi 100 UI FVIII-120 UI FVW----1件: 288 💬
62FANHDI 25 UI----1件: 288 💬
63Fanhdi 25 UI FVIII-30 UI FVW----1件: 288 💬
64FANHDI 250UI*1F 250UI+F 10ML----1件: 288 💬
65FANHDI 50 UI----1件: 288 💬
66Fanhdi 50 UI FVIII-60 UI FVW----1件: 288 💬
67FANHDI*INF FL 250UI+SIR SOLV+S----1件: 288 💬
68FANHDI*INF FL 500UI+SIR SOLV+S----1件: 288 💬
69FANHDI*INF FL1000UI+SIR SOLV+S----1件: 288 💬
70FANHDI*INF FL250UI+SIR SOLV+S----1件: 288 💬
71Fibrogammin P----1件: 288 💬
72Fibrogammin® P----1件: 288 💬
73Fibrogammin®P----1件: 288 💬
74FXIII Concentrate (Human)----1件: 288 💬
75FXIII Concentrate (Human) (FXIII)----1件: 288 💬
76Haemate P----1件: 288 💬
77Haemate P® (Human Coagulation Factor VIII)2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288 💬
78Haemate-P, Wilate1件: Von Willebrand factor human---1件: 288 💬
79Haemate® P 250----1件: 288 💬
80Hemlibra1件: Emicizumab1件: Emicizumab 💬2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288 💬
81Hemlibra®1件: Emicizumab1件: Emicizumab 💬2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288 💬
82HEMOFIX----1件: 288 💬
83HUMAN COAGULATION FACTOR VIII2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288 💬
84Human coagulation Factor VIII / von Willebrand Factor3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
85Human coagulation factor VIII associated with Von Willebrand factor (VWF)3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
86Human Coagulation Factor VIII, Von Willebrand Factor3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
87HUMAN COAGULATION FACTOR VIII, VON WILLEBRAND FACTOR COMPLEX3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
88HUMAN COAGULATION FACTOR VIII, VON WILLEBRAND HUMAN COAGULATION FACTOR2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288 💬
89Human Coagulation FACTOR X1件: Coagulation factor X human---1件: 288 💬
90Human factor X1件: Coagulation factor X human---1件: 288 💬
91HUMAN VON WILLEBRAND FACTOR1件: Von Willebrand factor human---1件: 288 💬
92Human von Willebrand factor (VWF) and coagulation factor VIII (FVIII)2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
93Human VWF/FVIII concentrate----1件: 288 💬
94Humate-P2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
95IL-111件: Oprelvekin1件: Oprelvekin 💬1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288 💬
96Interleukin 111件: Oprelvekin1件: Oprelvekin 💬1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288 💬
97Interleukin-111件: Oprelvekin1件: Oprelvekin 💬1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬2件: 96, 288 💬
98Marketed plasma-derived VWF/FVIII concentrate----1件: 288 💬
99Minirin1件: Desmopressin1件: Desmopressin 💬2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288 💬
100Minrin----1件: 288 💬
101Natriumchlorid1件: Sodium chloride1件: Sodium chloride 💬--1件: 288 💬
102Natriumchlorid 0,9 %1件: Sodium chloride1件: Sodium chloride 💬--1件: 288 💬
103Neumega (Oprelvekin, Interleukin 11, IL-11)1件: Oprelvekin1件: Oprelvekin 💬1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288 💬
104NN 1841----1件: 288 💬
105NN1841----1件: 288 💬
106OBI-1----1件: 288 💬
107OBIZUR1件: Susoctocog alfa1件: Susoctocog alfa 💬--1件: 288 💬
108Obyoctocog alfa----1件: 288 💬
109Octanate1件: Beroctocog alfa---1件: 288 💬
110OCTANATE 100 UI/ml, poudre et solvant pour solution injectable1件: Beroctocog alfa---1件: 288 💬
111OCTANATE 50 UI/ml, poudre et solvant pour solution injectable1件: Beroctocog alfa---1件: 288 💬
112OCTOCOG ALFA1件: Antihemophilic factor, human recombinant---1件: 288 💬
113Octostim----2件: 64, 288 💬
114Oprelvekin1件: Oprelvekin1件: Oprelvekin 💬1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288 💬
115Oprelvekin, Interleukin 11, IL-111件: Oprelvekin1件: Oprelvekin 💬1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288 💬
116Optivate----1件: 288 💬
117Optivate® (Human Coagulation Factor VIII)2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288 💬
118Physiologische Kochsalzlösung Fresenius - Infusionslösung----1件: 288 💬
119Phytomenadione1件: Phylloquinone---1件: 288 💬
120Plasma-derived FVIII/VWF concentrate----1件: 288 💬
121Prednisone1件: Prednisone1件: Prednisone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
122Prothrombin1件: Prothrombin---1件: 288 💬
123Prothrombin Complex Concentrate2件: Factor IX Complex (Human),
Prothrombin		---1件: 288 💬
124RAHF1件: Antihemophilic factor, human recombinant---1件: 288 💬
125Recombinant coagulation FVIII Fc – von Willebrand factor – XTEN fusion protein1件: Von Willebrand factor human---1件: 288 💬
126Recombinant coagulation FVIII Fc –von Willebrand factor – XTEN fusion protein1件: Von Willebrand factor human---1件: 288 💬
127Recombinant factor VIIII (rFVIII)----1件: 288 💬
128Recombinant Factor XIII1件: Factor XIII (human)---1件: 288 💬
129Recombinant Factor XIII (rFXIII)1件: Factor XIII (human)---2件: 97, 288 💬
130RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTO2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288 💬
131RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
132RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR - XTEN FUSION PROTEIN3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
133RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -XTEN FUSION PROTEIN3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
134Recombinant human von Willebrand Factor1件: Von Willebrand factor human---1件: 288 💬
135Recombinant interleukin-111件: Oprelvekin1件: Oprelvekin 💬1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288 💬
136Recombinant porcine coagulation factor VIII (B domain deleted)1件: Beroctocog alfa---1件: 288 💬
137Recombinant porcine coagulation factor VIII (B-domain deleted)1件: Beroctocog alfa---1件: 288 💬
138Recombinant von Willebrand Factor1件: Von Willebrand factor human---1件: 288 💬
139Recombinant von Willebrand Factor (rVWF)1件: Von Willebrand factor human---1件: 288 💬
140Recombinant von Willebrand Factor 1300IU1件: Von Willebrand factor human---1件: 288 💬
141Recombinant von Willebrand Factor 650IU1件: Von Willebrand factor human---1件: 288 💬
142Recombinant von Willebrand factor : recombinant FVIII (rVWF:rFVIII)1件: Von Willebrand factor human---1件: 288 💬
143Recomibnant human Von Willebrand Factor1件: Von Willebrand factor human---1件: 288 💬
144RFVIIa1件: Coagulation factor VIIa Recombinant Human---1件: 288 💬
145RFVIIa, rFVIIa + TXA1件: Coagulation factor VIIa Recombinant Human---1件: 288 💬
146RFVIII----1件: 288 💬
147Rituxan1件: Rituximab1件: Rituximab 💬1件: MS4A1 💬1件: Hematopoietic cell lineage 💬4件: 46, 60, 256, 288 💬
148RITUXIMAB1件: Rituximab1件: Rituximab 💬1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
149RO5534262 EMICIZUMAB1件: Emicizumab1件: Emicizumab 💬2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288 💬
150Rurioctocog alfa pegol1件: Rurioctocog alfa pegol1件: Rurioctocog alfa pegol 💬--1件: 288 💬
151RVWF----1件: 288 💬
152Saline solution----4件: 2, 34, 288, 299 💬
153Simvastatin1件: Simvastatin1件: Simvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
154Simvastatine1件: Simvastatin1件: Simvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 6, 13, 288 💬
155Sodium chloride2件: Chloride ion,
Sodium chloride		1件: Sodium chloride 💬--20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬
156SODIUM CHLORIDE SOLUTION 0.9%2件: Chloride ion,
Sodium chloride		1件: Sodium chloride 💬--4件: 51, 60, 288, 299 💬
157Standard of Care for Haemophilia A----1件: 288 💬
158Standard of Care FVIII Replacement therapy----1件: 288 💬
159Steroid----2件: 107, 288 💬
160TAK-672----1件: 288 💬
161Tranexamic acid1件: Tranexamic acid1件: Tranexamic acid 💬1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬7件: 46, 70, 215, 227, 274, 288, 299 💬
162VEYONDI 650IU powder and solvent for solution for injection----1件: 288 💬
163Veyvondi1件: Vonicog alfa1件: Vonicog alfa 💬--1件: 288 💬
164VEYVONDI 1300 IU powder and solvent for solution for injection1件: Vonicog alfa1件: Vonicog alfa 💬--1件: 288 💬
165VEYVONDI 1300I IU powder and solvent for solution for injection1件: Vonicog alfa1件: Vonicog alfa 💬--1件: 288 💬
166VEYVONDI 1300IU powder and solvent for solution for injection1件: Vonicog alfa1件: Vonicog alfa 💬--1件: 288 💬
167VEYVONDI 650IU powder and solvent for solution for injection1件: Vonicog alfa1件: Vonicog alfa 💬--1件: 288 💬
168Von willebrand factor1件: Von Willebrand factor human---2件: 64, 288 💬
169Von Willebrand factor (Recombinant)1件: Von Willebrand factor human---1件: 288 💬
170Von Willebrand factor and coagulation factor VIII in combination2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288 💬
171Von Willebrand Factor Antigen1件: Von Willebrand factor human---1件: 288 💬
172Von Willebrand Factor Ristocetin Cofactor1件: Von Willebrand factor human---1件: 288 💬
173Von Willebrand Faktor----1件: 288 💬
174Voncento2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288 💬
175Voncento, Biostate®2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288 💬
176Voncento®1件: Von Willebrand factor human---1件: 288 💬
177VONICOG ALFA1件: Vonicog alfa1件: Vonicog alfa 💬--1件: 288 💬
178VWD factor VIII concentrate1件: Beroctocog alfa---1件: 288 💬
179VWF gene analysis----1件: 288 💬
180VWF replacement therapy with Wilate1件: Von Willebrand factor human---1件: 288 💬
181VWF SD-35-DH----1件: 288 💬
182VWF-containing products----1件: 288 💬
183VWF/FVIII products----1件: 288 💬
184WILATE2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288 💬
185Wilate 10002件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288 💬
186WILATE 1000 I.U.1件: Von Willebrand factor human---1件: 288 💬
187WILATE 4502件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288 💬
188Wilate 5002件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288 💬
189WILATE 500 I.U.1件: Von Willebrand factor human---1件: 288 💬
190WILATE 9002件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288 💬
191WILATE® 4501件: Von Willebrand factor human---1件: 288 💬
192WILFACTIN----1件: 288 💬
193Willfact----1件: 288 💬
194Wiloctin----1件: 288 💬