Drug Description in Trials / DrugBank / KEGG DRUG


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No. DrugBank 薬物名(臨床試験情報から抽出) KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Abatacept 2件: ABATACEPT; Orencia1件: Abatacept 💬2件: CD80,
CD86 💬
13件: Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Ademetionine 2件: SAM-e; SAMe1件: Ademetionine 💬--2件: 6, 93 💬
3 Alkaline Phosphatase 1件: Alkaline Phosphatase---4件: 46, 93, 97, 172 💬
4 Atorvastatin 3件: ATORVASTATIN; Atorvastatin calcium; Lipitor1件: Atorvastatin 💬1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
5 Azathioprine 3件: Azathioprine; Azatioprina; Imuran1件: Azathioprine 💬--21件: 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
6 Baricitinib 2件: BARICITINIB; Olumiant1件: Baricitinib 💬2件: JAK1,
JAK2 💬
35件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬13件: 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
7 Bezafibrate 1件: Bezafibrate1件: Bezafibrate 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬7件: 20, 93, 94, 160, 296, 316, 324 💬
8 Budesonide 4件: BUDESONIDE; Entocort; Jorveza; Symbicort1件: Budesonide 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬9件: 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
9 Calcium 2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
10 Choline 1件: Choline1件: Choline 💬--4件: 93, 171, 193, 299 💬
11 Cilofexor 1件: Cilofexor---2件: 93, 94 💬
12 Colchicine 2件: COLCHICINA; Colchicine1件: Colchicine 💬9件: TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬
10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬7件: 2, 42, 46, 56, 93, 210, 266 💬
13 Cyclophosphamide 6件: Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; CYCLOPHOSPHAMIDE; Cyclophosphamidum; Cytoxan2件: Cyclophosphamide ,
Cyclophosphamide 💬
--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
14 Cyclosporine 10件: CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis1件: Cyclosporine 💬5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬
33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
15 Denosumab 3件: Denosumab; Prolia; XGEVA1件: Denosumab 💬1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
16 Elafibranor 1件: Elafibranor1件: Elafibranor 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬2件: 93, 94 💬
17 Emtricitabine 2件: Emtricitabine; TRUVADA1件: Emtricitabine 💬--4件: 25, 93, 265, 325 💬
18 Ezetimibe 2件: Ezetimibe; Ezetrol1件: Ezetimibe 💬1件: NPC1L1 💬1件: Fat digestion and absorption 💬4件: 49, 79, 93, 260 💬
19 Fenofibrate 1件: Fenofibrate1件: Fenofibrate 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬6件: 8, 79, 93, 94, 97, 265 💬
20 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318 💬
21 GSK-2330672 0件: ---1件: 93 💬
22 Hesperidin 1件: Hesperidin1件: Hesperidin 💬--2件: 46, 93 💬
23 Lopinavir 2件: Kaletra; Lopinavir1件: Lopinavir 💬--2件: 93, 265 💬
24 Magnesium 1件: Magnesium---19件: 6, 11, 13, 46, 51, 63, 64, 70, 93, 97, 111, 166, 225, 235, 284, 291, 296, 297, 298 💬
25 Methionine 3件: Butanoic acid; L-methionine; Methionine1件: Methionine 💬--6件: 34, 84, 93, 229, 298, 300 💬
26 Methotrexate 6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate1件: Methotrexate 💬2件: DHFR,
DHFR2 💬
5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
27 Methylprednisolone 4件: Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate1件: Methylprednisolone 💬1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
28 Minodronic acid 2件: Minodronate; Minodronic acid---4件: 6, 46, 93, 95 💬
29 Modafinil 2件: MODAFINIL; Provigil1件: Modafinil 💬--5件: 6, 13, 49, 93, 113 💬
30 Moexipril 1件: Moexipril1件: Moexipril 💬1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 93 💬
31 Mycophenolate mofetil 3件: CellCept; Mycophenolate mofetil; Mycophenolate mofetil TEVA1件: Mycophenolate mofetil 💬2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬34件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
32 Mycophenolic acid 5件: Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; MYCOPHENOLIC ACID; Myfortic1件: Mycophenolic acid 💬2件: IMPDH1,
IMPDH2 💬
4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬36件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
33 norUrsodeoxycholic acid 2件: Norucholic acid; NorUrsodeoxycholic Acid---2件: 93, 94 💬
34 Obeticholic acid 4件: 6-ECDCA; 6-ethylchenodeoxycholic acid; Obeticholic Acid; Ocaliva1件: Obeticholic acid 💬1件: NR1H4 💬1件: Bile secretion 💬3件: 93, 265, 296 💬
35 Pemafibrate 1件: Pemafibrate1件: Pemafibrate 💬1件: PPARA 💬10件: Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬1件: 93 💬
36 Pentoxifylline 1件: Pentoxifylline1件: Pentoxifylline 💬--12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298 💬
37 Phenylbutyric acid 4件: 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---14件: 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338 💬
38 Potassium 1件: Potassium1件: Potassium 💬--13件: 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
39 Pyridoxine 2件: PYRIDOXINE; Vitamin B61件: Pyridoxine 💬--5件: 6, 93, 145, 206, 320 💬
40 Raltegravir 2件: ISENTRESS; Raltegravir1件: Raltegravir 💬--4件: 13, 26, 93, 265 💬
41 Rifampicin 2件: Rifampicin; Rifampin1件: Rifampin 💬--9件: 6, 13, 17, 46, 84, 86, 93, 299, 338 💬
42 Rifaximin 3件: Rifaximin; RIFAXIMINA; Xifaxan1件: Rifaximin 💬--9件: 6, 65, 93, 94, 96, 97, 99, 296, 299 💬
43 Risedronic acid 3件: Risedronate; Risedronate Sodium; Risedronic acid1件: Risedronic acid 💬1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
44 Rituximab 6件: MABTHERA; Rituxan; Rituximab; Rixathon; Ruxience; TRUXIMA1件: Rituximab 💬1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
45 Saroglitazar 1件: Saroglitazar---1件: 93 💬
46 Seladelpar 1件: SELADELPAR1件: Seladelpar 💬1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94 💬
47 Setanaxib 1件: SETANAXIB---1件: 93 💬
48 Tauroursodeoxycholic acid 4件: TAUROURSODEOXYCHOLIC ACID; Taurursodiol; TUDCA; Ursodoxicoltaurine1件: Taurursodiol 💬--3件: 2, 93, 299 💬
49 Tenofovir 1件: Tenofovir1件: Tenofovir 💬--6件: 2, 13, 25, 93, 265, 325 💬
50 Tenofovir disoproxil 4件: Tenofovir; Tenofovir disoproxil; Tenofovir Disoproxil Fumarate; TRUVADA---2件: 93, 265 💬
51 Tetrathiomolybdate 1件: Tetrathiomolybdate---3件: 85, 93, 171 💬
52 Thiamine 2件: Thiamine; Vitamin B11件: Thiamine 💬--4件: 8, 93, 145, 265 💬
53 Tigecycline 1件: Tigecycline1件: Tigecycline 💬--1件: 93 💬
54 Tropifexor 1件: Tropifexor1件: Tropifexor 💬1件: NR1H4 💬1件: Bile secretion 💬1件: 93 💬
55 Ursodeoxycholic acid 4件: UDCA; Ursodeoxycholic Acid; Ursodiol; Ursofalk1件: Ursodiol 💬1件: NR1H4 💬1件: Bile secretion 💬14件: 6, 8, 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
56 Ustekinumab 2件: STELARA; Ustekinumab1件: Ustekinumab 💬3件: IL12A,
IL12B,
IL23A 💬
28件: African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
57 Vitamin D 3件: Calciferol; Cod liver oil; Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299 💬
58 Volixibat 1件: VOLIXIBAT1件: Volixibat 💬--2件: 93, 94 💬
59 Zoledronic acid 4件: Aclasta; Zoledronate; Zoledronic acid; Zometa2件: Zoledronic acid ,
Zoledronic acid 💬
1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬