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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
指定難病告示番号
1
JAK2
💬
1.
JAK2
×
Name
Full Name
JAK2
Janus kinase 2
24件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Signaling pathways regulating pluripotency of stem cells
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Cholinergic synapse
,
Prolactin signaling pathway
,
Adipocytokine signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Leishmaniasis
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Influenza A
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Pathways in cancer
,
Chemical carcinogenesis - receptor activation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Lipid and atherosclerosis
24件:
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling path
...
Ruxolitinib
Ruxolitinib
💬
1.
JAK2
×
Name
Other Names
Ruxolitinib
Ruxolitinib (USAN/INN)
ルキソリチニブ
Ruxolitinib
3件:
60
60
,
65
,
228
💬
1.
JAK2
×
告示番号
日本語名
英語名
60
再生不良性貧血
Aplastic anemia
65
原発性免疫不全症候群
Primary immunodeficiency
228
閉塞性細気管支炎
Bronchiolitis obliterans
2
JAK2
💬
2.
JAK2
×
Name
Full Name
JAK2
Janus kinase 2
24件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Signaling pathways regulating pluripotency of stem cells
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Cholinergic synapse
,
Prolactin signaling pathway
,
Adipocytokine signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Leishmaniasis
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Influenza A
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Pathways in cancer
,
Chemical carcinogenesis - receptor activation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Lipid and atherosclerosis
24件:
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling path
...
Tofacitinib
Tofacitinib
💬
2.
JAK2
×
Name
Other Names
Tofacitinib
Tofacitinib (USAN)
Tasocitinib
トファシチニブ
タソシチニブ
Tofacitinib
15件:
11
11
,
40
,
44
,
46
,
49
,
50
,
51
,
53
,
65
,
84
,
96
,
97
,
107
,
271
,
300
💬
2.
JAK2
×
告示番号
日本語名
英語名
11
重症筋無力症
Myasthenia gravis
40
高安動脈炎;大動脈炎症候群
Takayasu arteritis
44
多発血管炎性肉芽腫症;ウェゲナー肉芽腫症
Wegener granulomatosis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
50
皮膚筋炎／多発性筋炎
Dermatomyositis
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
65
原発性免疫不全症候群
Primary immunodeficiency
84
サルコイドーシス
Sarcoidosis
96
クローン病;回腸末端炎
Crohn disease
97
潰瘍性大腸炎
Ulcerative colitis
107
若年性特発性関節炎
Juvenile idiopathic arthritis
271
強直性脊椎炎
Ankylosing spondylitis
300
IgG4関連疾患
IgG4-related disease
3
JAK2
💬
3.
JAK2
×
Name
Full Name
JAK2
Janus kinase 2
24件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Signaling pathways regulating pluripotency of stem cells
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Cholinergic synapse
,
Prolactin signaling pathway
,
Adipocytokine signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Leishmaniasis
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Influenza A
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Pathways in cancer
,
Chemical carcinogenesis - receptor activation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Lipid and atherosclerosis
24件:
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling path
...
Baricitinib
Baricitinib
💬
3.
JAK2
×
Name
Other Names
Baricitinib
Baricitinib (JAN/USAN/INN)
Olumiant (TN)
OTHER BARICITINIB
バリシチニブ
オルミエント
Baricitinib
13件:
2
2
,
41
,
46
,
49
,
50
,
51
,
53
,
93
,
107
,
162
,
265
,
269
,
325
💬
3.
JAK2
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
41
巨細胞性動脈炎;側頭動脈炎
Giant cell arteritis
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
50
皮膚筋炎／多発性筋炎
Dermatomyositis
51
全身性強皮症
Scleroderma
53
シェーグレン症候群
Sjogren syndrome
93
原発性胆汁性胆管炎
Primary biliary cholangitis
107
若年性特発性関節炎
Juvenile idiopathic arthritis
162
類天疱瘡（後天性表皮水疱症を含む。）
Pemphigoid
265
脂肪萎縮症
Lipodystrophy
269
化膿性無菌性関節炎・壊疽性膿皮症・アクネ症候群;PAPA症候群
Pyogenic arthritis
325
遺伝性自己炎症疾患
Hereditary autoinflammatory syndrome
4
JAK2
💬
4.
JAK2
×
Name
Full Name
JAK2
Janus kinase 2
24件:
EGFR tyrosine kinase inhibitor resistance
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling pathway
,
Necroptosis
,
Signaling pathways regulating pluripotency of stem cells
,
JAK-STAT signaling pathway
,
Th1 and Th2 cell differentiation
,
Th17 cell differentiation
,
Cholinergic synapse
,
Prolactin signaling pathway
,
Adipocytokine signaling pathway
,
AGE-RAGE signaling pathway in diabetic complications
,
Growth hormone synthesis, secretion and action
,
Leishmaniasis
,
Toxoplasmosis
,
Tuberculosis
,
Hepatitis B
,
Influenza A
,
Kaposi sarcoma-associated herpesvirus infection
,
Herpes simplex virus 1 infection
,
Pathways in cancer
,
Chemical carcinogenesis - receptor activation
,
PD-L1 expression and PD-1 checkpoint pathway in cancer
,
Lipid and atherosclerosis
24件:
EGFR tyrosine kinase inhibitor resistance
,
Chemokine signaling pathway
,
PI3K-Akt signaling path
...
Peficitinib
Peficitinib
💬
4.
JAK2
×
Name
Other Names
Peficitinib
Peficitinib (USAN/INN)
ペフィシチニブ
Peficitinib
1件:
46
46
💬
4.
JAK2
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis