Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 💬1件: Acetaminophen (APAP)2件: Acetaminophen; Paracetamol2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬17件: 3, 6, 11, 13, 19, 34, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 Apabetalone 💬
(Apabetalone (USAN/INN))		1件: Apabetalone (Apabetalone)1件: Apabetalone--1件: 86 💬
3 Apadamtase alfa 💬
(Apadamtase alfa (INN), Apadamtase alfa (genetical recombination) (JAN))		1件: Apadamtase alfa (Apadamtase alfa)2件: Apadamtase alfa; Radamts-131件: ADAMTS13 💬 1件: Platelet activation 💬1件: 64 💬
4 Apadamtase alfa and cinaxadamtase alfa 💬
(Apadamtase alfa and cinaxadamtase alfa, Apadamtase alfa (genetical recombination) and cinaxadamtase alfa (genetical recombination))		1件: Apadamtase alfa (Apadamtase alfa)2件: Apadamtase alfa; Radamts-131件: ADAMTS13 💬 1件: Platelet activation 💬1件: 64 💬
5 Apitegromab 💬
(Apitegromab (USAN))		1件: Apitegromab (Apitegromab)1件: Apitegromab1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
6 Apixaban 💬
(Apixaban (JAN/USAN/INN), APIXABAN)		1件: Apixaban (Apixaban)1件: Apixaban1件: F10 💬 1件: Complement and coagulation cascades 💬2件: 222, 279 💬
7 Aplindore fumarate 💬
(Aplindore fumarate (USAN))		1件: Aplindore (Aplindore fumarate)1件: Aplindore2件: DRD2,
DRD3 💬 		10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
8 Apomorphine 💬
(Apomorphine (BAN))		1件: Apomorphine (Apomorphin)2件: Apomorphine; Apomorphine hydrochloride2件: DRD1,
DRD2 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7 💬
9 Apomorphine hydrochloride 💬
(Apomorphine hydrochloride (USP), Apomorphine hydrochloride hydrate (JAN), Apokyn (TN), APOKYN, APOMORPHINE HYDROCLORIDE)		1件: Apomorphine (Apomorphin)2件: Apomorphine; Apomorphine hydrochloride2件: DRD1,
DRD2 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 5, 6, 7 💬
10 Apraclonidine 💬
(Apraclonidine (INN))		1件: Apraclonidine (Apraclonidine hydrochloride)0件: 3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬-
11 Apraclonidine hydrochloride 💬
(Apraclonidine hydrochloride (JAN/USP), APRACLONIDINE)		1件: Apraclonidine (Apraclonidine hydrochloride)0件: 3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬-
12 Apratastat 💬
(Apratastat (USAN/INN))		1件: Apratastat (Apratastat)1件: Apratastat2件: ADAM17,
MMP13 💬 		9件: Alzheimer disease, Coronavirus disease - COVID-19, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway, TNF signaling pathway 💬1件: 46 💬
13 Apremilast 💬
(Apremilast (JAN/USAN), APREMILAST)		1件: Apremilast (Aprémilast)1件: Apremilast4件: PDE4,
PDE4,
PDE4,
PDE4 💬 		4件: Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬7件: 46, 50, 56, 97, 107, 162, 271 💬
14 Aprotinin 💬
(Aprotinin (USP/INN))		1件: Aprotinin (Aprotinina)1件: Aprotinin--1件: 28 💬
15 Bupropion hydrobromide 💬
(Aplenzin (TN), APLENZIN)		1件: Bupropion2件: Bupropion; Bupropion hydrochloride2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬4件: 8, 21, 96, 171 💬
16 Captopril 💬
(Apopril (TN))		1件: Captopril1件: Captopril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬2件: 17, 86 💬
17 Dalfampridine 💬1件: Dalfampridine (4-AP)5件: 4-aminopyridine; 4-AP; Dalfampridine; Fampridina; Fampridine4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬4件: 3, 4, 13, 14 💬
18 Esuberaprost 💬1件: Esuberaprost (Aps-314d free acid)1件: Esuberaprost1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬1件: 86 💬
19 Esuberaprost sodium 💬1件: Esuberaprost (Aps-314d free acid)1件: Esuberaprost1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬1件: 86 💬
20 Factor IX complex 💬1件: Factor IX Complex (Human) (APCC)1件: Prothrombin complex concentrate--1件: 288 💬
21 Hydralazine hydrochloride 💬
(Apresoline (TN))		1件: Hydralazine1件: Hydralazine--1件: 67 💬
22 Ilofotase alfa 💬1件: Recombinant human alkaline phosphatase (Human recombinant AP)0件: 1件: E3.1.3.1 💬 2件: Folate biosynthesis, Thiamine metabolism 💬-
23 Lorcaserin hydrochloride 💬
(APD-356)		1件: Lorcaserin1件: Lorcaserin1件: HTR2 💬 6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 140 💬
24 Mesalamine 💬
(Apriso (TN), APRISO)		1件: Mesalazine6件: 5-aminosalicylic acid; 5-ASA; Mesalamine; Mesalazina; Mesalazine; Mesalazinum--4件: 46, 96, 97, 164 💬
25 Methylphenidate hydrochloride 💬
(APTENSIO XR)		1件: Methylphenidate2件: Methylphenidate; Methylphenidate hydrochloride2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬5件: 6, 13, 34, 84, 113 💬
26 Piperazine adipate 💬
(Camin AP (TN))		1件: Piperazine1件: Piperazine--1件: 272 💬
27 Royal jelly 💬1件: Royal jelly (Apis Mellifera Secretion)1件: Royal jelly--1件: 49 💬
28 Sildenafil 💬
(Aphrodil (TN))		1件: Sildenafil3件: Sildenafil; Sildenafil citrate; Sildenafilo1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
29 Tipranavir 💬
(Aptivus (TN), APTIVUS)		1件: Tipranavir1件: Tipranavir--1件: 265 💬
30 Trifluoperazine 💬
(Apo-trifluoperazine (TN))		1件: Trifluoperazine1件: Trifluoperazine1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284 💬
31 Trihexyphenidyl 💬
(Apo-trihex (TN))		1件: Trihexyphenidyl1件: Trihexyphenidyl5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6 💬