Drug Description in Trials / DrugBank / KEGG DRUG


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No. KEGG DRUG DrugBank 薬物名(臨床試験情報から抽出) KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Serine 💬 1件: Serine2件: L-Serine; Serine; --4件: 2, 6, 86, 96 💬
2 Sucrose 💬 1件: Sucrose1件: Sucrose; --3件: 62, 96, 97 💬
3 Sorbitol solution 💬 1件: Sorbitol3件: D-glucitol; D-SORBITOL; Sorbitol; --3件: 10, 28, 299 💬
4 Salicylic acid 💬 1件: Salicylic acid2件: 2-Hydroxybenzoic acid; Salicylic acid; --1件: 97 💬
5 Sulindac 💬 1件: Sulindac1件: Sulindac; 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206 💬
6 Scopolamine 💬 1件: Scopolamine1件: Scopolamine; 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬
13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 2 💬
7 Salsalate 💬 1件: Salsalate1件: Salsalate; 2件: PTGS1,
PTGS2 💬
23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5 💬
8 Saquinavir 💬 1件: Saquinavir1件: Saquinavir; --2件: 86, 265 💬
9 Simvastatin 💬 1件: Simvastatin3件: SIMVASTATIN; Simvastatina; Simvastatine; 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
10 Spironolactone 💬 1件: Spironolactone1件: Spironolactone; 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬8件: 46, 58, 67, 86, 113, 210, 218, 225 💬
11 Stanozolol 💬 1件: Stanozolol1件: Stanozolol; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 60 💬
12 Stavudine 💬 1件: Stavudine1件: Stavudine; --1件: 265 💬
13 Sucralfate 💬 1件: Sucralfate1件: Sucralfate; --1件: 98 💬
14 Sulfamethoxazole 💬 1件: Sulfamethoxazole3件: Bactrim; Sulfamethoxazole; Sulphamethoxazole; --5件: 44, 49, 61, 85, 299 💬
15 Sulfasalazine 💬 1件: Sulfasalazine3件: Salazosulfapyridine; Salicylazosulfapyridine; SULFASALAZINE; --6件: 46, 86, 94, 107, 270, 271 💬
16 Sevoflurane 💬 1件: Sevoflurane1件: Sevoflurane; --7件: 6, 21, 22, 34, 98, 225, 296 💬
17 Succimer 💬 1件: Succimer1件: DMSA; --1件: 171 💬
18 Sulfadoxine 💬 1件: Sulfadoxine1件: Sulfadoxine; --1件: 65 💬
19 Sirolimus 💬 1件: Sirolimus3件: Rapamune; Rapamycin; Sirolimus; 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
20 Sodium fluoride 💬 1件: Sodium fluoride1件: Sodium fluoride; --1件: 51 💬
21 Sodium lauryl sulfate 💬 1件: Sodium lauryl sulfate0件: ---
22 Sodium bicarbonate 💬 1件: Sodium bicarbonate1件: Sodium Bicarbonate; --1件: 299 💬
23 Sulpiride 💬 1件: Sulpiride0件: 1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬-
24 Sodium acetate 💬 1件: Sodium acetate1件: Sodium acetate; --2件: 81, 251 💬
25 Sodium citrate hydrate 💬 1件: Sodium citrate1件: Sodium citrate; --4件: 67, 214, 215, 235 💬
26 Silodosin 💬 1件: Silodosin2件: Silodosin; Silodyx; 1件: ADRA1A 💬7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 6, 13 💬
27 Sodium chloride 💬 1件: Sodium chloride6件: Lactated Ringers; Natriumchlorid; REBIF; SALINE; Sodium chloride; SPORANOX; --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬
28 Sertraline 💬 1件: Sertraline1件: Sertraline; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 206 💬
29 Sesame oil 💬 1件: Sesame oil1件: Sesame oil; --1件: 3 💬
30 Selegiline 💬 1件: Selegiline2件: SELEGILINE; Zelapar; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6 💬
31 Sivelestat 💬 1件: Sivelestat1件: Sivelestat; 1件: ELANE 💬3件: Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬3件: 13, 85, 96 💬
32 Sodium iodide 💬 1件: Sodium iodide1件: Sodium iodide; --1件: 34 💬
33 Sodium iodide I 123 💬 1件: Sodium iodide1件: Sodium iodide; --1件: 34 💬
34 Salmeterol 💬 1件: Salmeterol1件: Salmeterol; 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 299 💬
35 Sargramostim 💬 1件: Sargramostim2件: Leukine; Sargramostim; 1件: CSF2RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬7件: 6, 28, 60, 62, 96, 229, 285 💬
36 Simethicone 💬 1件: Simethicone1件: Simethicone; --2件: 13, 96 💬
37 Sodium citrate 💬 1件: Sodium citrate1件: Sodium citrate; --4件: 67, 214, 215, 235 💬
38 Sodium dichloroacetate 💬 1件: Sodium dichloroacetate1件: Dichloroacetate Sodium; 3件: PDK2,
PDK3,
PDK4 💬
1件: Diabetic cardiomyopathy 💬1件: 86 💬
39 Sodium fluoride F 18 💬 1件: Fluorine F-181件: FLUORINE-18; --1件: 41 💬
40 Sodium iodide I 125 💬 1件: Sodium iodide1件: Sodium iodide; --1件: 34 💬
41 Sodium oxybate 💬 1件: Sodium oxybate1件: Sodium Oxybate; --2件: 6, 149 💬
42 Sodium sulfate 💬 1件: Sodium sulfate1件: Sodium sulfate; --1件: 28 💬
43 Stamulumab 💬 1件: Stamulumab1件: MYO-029; 1件: MSTN 💬1件: Cytokine-cytokine receptor interaction 💬1件: 113 💬
44 Stannsoporfin 💬 1件: Stannsoporfin1件: Tin mesoporphyrin; 2件: HMOX1,
HMOX2 💬
10件: Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬1件: 254 💬
45 Stiripentol 💬 1件: Stiripentol2件: DIACOMIT; Stiripentol; --1件: 140 💬
46 Sufentanil 💬 1件: Sufentanil1件: Sufentanil; 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬2件: 70, 280 💬
47 Sulfachlorpyridazine 💬 1件: Sulfachlorpyridazine0件: ---
48 Sulfur hexafluoride 💬 1件: Sulfur hexafluoride3件: SonoVue; Sulfur hexafluoride; Sulphur hexafluoride; --2件: 96, 215 💬
49 Senna leaf 💬 1件: Senna leaf1件: Senna; --1件: 291 💬
50 Sodium tetradecyl sulfate 💬 1件: Sodium tetradecyl sulfate0件: ---
51 Sitaxentan 💬 1件: Sitaxentan3件: Sitaxentan; Sitaxsentan; Thelin; 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
52 Somatostatin 💬 1件: Somatostatin1件: Somatostatin; 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬
4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 78 💬
53 Strontium ranelate 💬 1件: Strontium ranelate1件: Strontium ranelate; --1件: 78 💬
54 Sapropterin 💬 1件: Sapropterin5件: 6R-BH4; KUVAN; Sapropterin; SAPROPTERIN DIHYDROCHLORIDE; Tetrahydrobiopterin; --3件: 86, 124, 240 💬
55 Sevelamer 💬 1件: Sevelamer1件: Sevelamer; --2件: 235, 238 💬
56 Sildenafil 💬 1件: Sildenafil6件: Mysildecard; Revatio; Sildenafil; Sildenafil Citrate; SILDENAFILO; VIAGRA; 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬17件: 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
57 Sitagliptin 💬 1件: Sitagliptin1件: Sitagliptin; 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299 💬
58 Solifenacin 💬 1件: Solifenacin2件: Solifenacin; Solifenacin Succinate; 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬3件: 6, 13, 53 💬
59 Somatorelin 💬 1件: Somatorelin2件: GHRH; Somatorelin; 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 13, 78 💬
60 Sorafenib 💬 1件: Sorafenib2件: Nexavar; Sorafenib; 8件: BRAF,
FLT3,
FLT4,
KDR,
KIT,
PDGFRB,
RAF1,
RET 💬
89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, VEGF signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬2件: 34, 86 💬
61 Spectinomycin 💬 1件: Spectinomycin0件: ---
62 Sulfanilamide 💬 1件: Sulfanilamide0件: ---
63 Sulodexide 💬 1件: Sulodexide0件: 2件: SERPINC1,
SERPIND1 💬
1件: Complement and coagulation cascades 💬-
64 Sunitinib 💬 1件: Sunitinib2件: Sunitinib; Sunitinib malate; 9件: CSF1R,
FLT1,
FLT3,
FLT4,
KDR,
KIT,
PDGFRA,
PDGFRB,
RET 💬
36件: Acute myeloid leukemia, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Choline metabolism in cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Fluid shear stress and atherosclerosis, Focal adhesion, Gap junction, Glioma, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Thyroid cancer, Transcriptional misregulation in cancer, VEGF signaling pathway, Viral protein interaction with cytokine and cytokine receptor 💬2件: 28, 34 💬
65 Saxagliptin 💬 1件: Saxagliptin1件: Saxagliptin; 1件: DPP4 💬1件: Protein digestion and absorption 💬1件: 299 💬
66 Sinecatechins 💬 1件: Sinecatechins1件: Veregen; --1件: 160 💬
67 Sunflower oil 💬 1件: Sunflower oil1件: Sunflower Oil; --2件: 46, 299 💬
68 Serlopitant 💬 1件: Serlopitant1件: Serlopitant; 1件: TACR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 36 💬
69 Sobetirome 💬 1件: Sobetirome1件: Sobetirome; 1件: THRB 💬2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬1件: 20 💬
70 Saracatinib 💬 1件: Saracatinib1件: Saracatinib; 2件: ABL1,
SRC 💬
49件: Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, C-type lectin receptor signaling pathway, Cell cycle, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, GnRH signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MicroRNAs in cancer, Mitophagy - animal, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Oxytocin signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Platelet activation, Prolactin signaling pathway, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬3件: 6, 89, 272 💬
71 Selumetinib 💬 1件: Selumetinib2件: Koselugo; Selumetinib; 2件: MAP2K1,
MAP2K2 💬
89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 34 💬
72 Sifalimumab 💬 1件: Sifalimumab1件: Sifalimumab; 13件: IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬
25件: Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬1件: 49 💬
73 Siltuximab 💬 1件: Siltuximab1件: Siltuximab; 1件: IL6 💬51件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 28, 331 💬
74 Sotatercept 💬 1件: Sotatercept1件: Sotatercept; 1件: ACVR2A 💬4件: Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬2件: 86, 284 💬
75 Sotrastaurin 💬 1件: Sotrastaurin1件: Sotrastaurin; 4件: PRKCD,
PRKCE,
PRKCH,
PRKCQ 💬
29件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Aldosterone synthesis and secretion, Apelin signaling pathway, Autophagy - animal, C-type lectin receptor signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Diabetic cardiomyopathy, Estrogen signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Inflammatory mediator regulation of TRP channels, Insulin resistance, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Prion disease, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 97 💬
76 Secukinumab 💬 1件: Secukinumab2件: COSENTYX; SECUKINUMAB; 1件: IL17A 💬6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
77 Selexipag 💬 1件: Selexipag2件: SELEXIPAG; Uptravi; 1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬5件: 51, 70, 84, 86, 88 💬
78 Semaglutide 💬 1件: Semaglutide1件: Semaglutide; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 6 💬
79 Sirukumab 💬 1件: Sirukumab1件: Sirukumab; 1件: IL6 💬51件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 41, 46 💬
80 Suvorexant 💬 1件: Suvorexant1件: Suvorexant; 2件: HCRTR1,
HCRTR2 💬
1件: Neuroactive ligand-receptor interaction 💬3件: 5, 6, 13 💬
81 Safinamide 💬 1件: Safinamide3件: Safinamida; SAFINAMIDE; Xadago; 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17 💬
82 Sarilumab 💬 1件: Sarilumab4件: Kevzara; REGN88; SAR153191; Sarilumab; 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬5件: 41, 46, 84, 107, 271 💬
83 Sacubitril 💬 1件: Sacubitril2件: Entresto; Sacubitril; 1件: MME 💬4件: Alzheimer disease, Hematopoietic cell lineage, Protein digestion and absorption, Renin-angiotensin system 💬2件: 58, 222 💬
84 Sofosbuvir 💬 1件: Sofosbuvir1件: Sofosbuvir; --1件: 19 💬
85 Sebelipase alfa 💬 1件: Sebelipase alfa4件: KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa; 1件: LIPA 💬3件: Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬1件: 19 💬
86 Sodium glycerophosphate 💬 1件: Sodium glycerophosphate1件: Smofkabiven; --1件: 66 💬
87 Susoctocog alfa 💬 1件: Susoctocog alfa1件: OBIZUR; --1件: 288 💬
88 Selonsertib 💬 1件: Selonsertib1件: Selonsertib; 1件: MAP3K5 💬20件: Alcoholic liver disease, Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Huntington disease, Lipid and atherosclerosis, MAPK signaling pathway, Neurotrophin signaling pathway, Non-alcoholic fatty liver disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Protein processing in endoplasmic reticulum, Sphingolipid signaling pathway, Spinocerebellar ataxia, TNF signaling pathway, Thermogenesis, Tight junction 💬1件: 86 💬
89 Somatrogon 💬 1件: Somatrogon2件: Ngenla; Somatrogon; --1件: 78 💬
90 Satralizumab 💬 1件: Satralizumab3件: Enspryng; Sapelizumab; Satralizumab; 1件: IL6R 💬12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬3件: 11, 13, 86 💬
91 Somavaratan 💬 1件: Somavaratan1件: Somavaratan; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78 💬
92 Somapacitan 💬 1件: Somapacitan2件: Sogroya; Somapacitan; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 78, 195 💬
93 Selinexor 💬 1件: Selinexor1件: Selinexor; 1件: XPO1 💬5件: Human T-cell leukemia virus 1 infection, Influenza A, Nucleocytoplasmic transport, Ribosome biogenesis in eukaryotes, Viral life cycle - HIV-1 💬1件: 28 💬
94 Seladelpar 💬 1件: Seladelpar1件: SELADELPAR; 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬2件: 93, 94 💬
95 Siponimod 💬 1件: Siponimod2件: Mayzent; Siponimod; 2件: S1PR1,
S1PR5 💬
3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬2件: 13, 50 💬
96 Sutimlimab 💬 1件: Sutimlimab1件: Sutimlimab; 1件: C1S 💬5件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬1件: 61 💬
97 Soticlestat 💬 1件: Soticlestat1件: SOTICLESTAT; 1件: CYP46A1 💬1件: Primary bile acid biosynthesis 💬2件: 140, 144 💬
98 Sparsentan 💬 1件: Sparsentan1件: SPARSENTAN; 2件: AGTR1,
EDNRA 💬
17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 66, 218, 222 💬
99 Sibofimloc 💬 1件: Sibofimloc1件: Sibofimloc; --1件: 96 💬
100 Setmelanotide 💬 1件: Setmelanotide1件: Setmelanotide; 1件: MC4R 💬1件: Neuroactive ligand-receptor interaction 💬2件: 202, 265 💬
101 Spesolimab 💬 1件: Spesolimab1件: SPESOLIMAB; 1件: IL1RL2 💬1件: Cytokine-cytokine receptor interaction 💬3件: 37, 96, 97 💬