Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Tryptophan 💬1件: Tryptophan2件: Propanoic acid; Tryptophan--1件: 6 💬
2 Tyrosine 💬1件: Tyrosine4件: Alanine; L-Tyrosine; Propanoic acid; Tyrosine--4件: 6, 86, 111, 298 💬
3 Threonine 💬1件: Threonine1件: Threonine--2件: 86, 97 💬
4 Taurine 💬1件: Taurine1件: Taurine--1件: 337 💬
5 Trypsin, crystallized 💬1件: Trypsin1件: Trypsin--1件: 96 💬
6 Tobramycin 💬1件: Tobramycin9件: Bethkis; TOBI; TOBI PODHALER; TOBRAMICINA; TOBRAMYCIN; Tobramycin inhalation solution; TOBRAMYCIN SULFATE; Tobramycine; Tobramycinum--1件: 299 💬
7 Testosterone 💬1件: Testosterone1件: Testosterone1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬8件: 1, 2, 3, 13, 60, 76, 78, 113 💬
8 Tretinoin 💬1件: Tretinoin5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID3件: PML,
RARA,
RARB 💬 		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231 💬
9 Tacrolimus 💬1件: Tacrolimus2件: Prograf; Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
10 Trimethoprim 💬1件: Trimethoprim2件: Bactrim; Trimethoprim--7件: 36, 44, 49, 60, 61, 85, 299 💬
11 Tetracycline 💬1件: Tetracycline2件: Tetracyclin; Tetracycline--5件: 13, 36, 46, 53, 97 💬
12 Theophylline 💬1件: Theophylline1件: Theophylline18件: ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		23件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 236, 299 💬
13 Timolol 💬1件: Timolol2件: Timolol; TIMOLOL MALEATE2件: ADRB1,
ADRB2 💬 		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227 💬
14 Triacetin 💬1件: Triacetin1件: Glyceryl triacetate--1件: 307 💬
15 Triamcinolone 💬1件: Triamcinolone4件: Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
16 Tromethamine 💬1件: Tromethamine4件: Tham; Tris; Trometamol; Tromethamine--5件: 51, 96, 97, 226, 299 💬
17 Tropicamide 💬1件: Tropicamide1件: Tropicamide5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 6 💬
18 Topiramate 💬1件: Topiramate2件: TOPAMAX; TOPIRAMATE36件: CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		53件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 6, 97, 140, 144, 156, 193 💬
19 Thiotepa 💬1件: Thiotepa1件: Thiotepa--12件: 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬
20 Telmisartan 💬1件: Telmisartan1件: Telmisartan1件: AGTR1 💬 16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬2件: 66, 67 💬
21 Tolterodine 💬1件: Tolterodine1件: Tolterodine1件: CHRM3 💬 11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53 💬
22 Tazobactam 💬1件: Tazobactam1件: TAZOBACTAM--1件: 299 💬
23 Thalidomide 💬1件: Thalidomide1件: Thalidomide1件: TNF 💬 67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
24 Tolcapone 💬1件: Tolcapone3件: Tasmar; Tolcapon; Tolcapone1件: COMT 💬 4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127 💬
25 Testosterone enanthate 💬1件: Testosterone enanthate1件: Testosterone Enanthate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
26 Testosterone propionate 💬1件: Testosterone propionate1件: Testosterone propionate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
27 Thymol 💬1件: Thymol1件: Thymol--1件: 13 💬
28 Tigecycline 💬1件: Tigecycline1件: Tigecycline--1件: 93 💬
29 Tranexamic acid 💬1件: Tranexamic acid1件: Tranexamic acid1件: PLG 💬 4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬7件: 46, 70, 215, 227, 274, 288, 299 💬
30 Tolfenamic acid 💬1件: Tolfenamic acid1件: Tolfenamic Acid2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 5 💬
31 Tolvaptan 💬1件: Tolvaptan3件: Jinarc; Samsca; TOLVAPTAN1件: AVPR2 💬 3件: Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬4件: 67, 72, 86, 225 💬
32 Tegafur 💬1件: Tegafur0件: 1件: TYMS 💬 5件: Antifolate resistance, Metabolic pathways, Nucleotide metabolism, One carbon pool by folate, Pyrimidine metabolism 💬-
33 Terguride 💬1件: Terguride1件: Terguride2件: DRD2,
PRL 💬 		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 51, 86 💬
34 Tamibarotene 💬1件: Tamibarotene1件: Tamibarotene1件: RARA 💬 5件: Acute myeloid leukemia, Estrogen signaling pathway, Pathways in cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬2件: 26, 96 💬
35 Trifluoperazine maleate 💬1件: Trifluoperazine1件: Trifluoperazine1件: DRD2 💬 8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284 💬
36 Tadalafil 💬1件: Tadalafil4件: Adcirca; Cialis; Tadalafil; TADALAFILO1件: PDE5A 💬 3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210 💬
37 Tranilast 💬1件: Tranilast1件: Tranilast--4件: 46, 84, 106, 113 💬
38 Teicoplanin 💬1件: Teicoplanin1件: Teicoplanin--2件: 70, 299 💬
39 Tulobuterol 💬1件: Tulobuterol1件: Tulobuterol1件: ADRB2 💬 9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6 💬
40 Tocopherol 💬1件: Tocopherol2件: Tocoferol; TOCOPHEROL--6件: 13, 49, 90, 206, 257, 298 💬
41 Terbinafine 💬1件: Terbinafine1件: Terbinafine--3件: 96, 97, 271 💬
42 Tocilizumab 💬1件: Tocilizumab3件: ACTEMRA; RoActemra; TOCILIZUMAB1件: IL6R 💬 12件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬21件: 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
43 Talampanel 💬1件: Talampanel1件: Talampanel4件: GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		16件: Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬2件: 2, 6 💬
44 Talniflumate 💬1件: Talniflumate1件: Talniflumate--1件: 299 💬
45 Tipifarnib 💬1件: Tipifarnib1件: Tipifarnib2件: FNTA,
FNTB 💬 		1件: Terpenoid backbone biosynthesis 💬1件: 34 💬
46 Teduglutide 💬1件: Teduglutide1件: Teduglutide1件: GLP2R 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 96 💬
47 Tefibazumab 💬1件: Tefibazumab1件: Tefibazumab--1件: 299 💬
48 Temozolomide 💬1件: Temozolomide1件: Temozolomide--1件: 34 💬
49 Temsirolimus 💬1件: Temsirolimus1件: Temsirolimus1件: MTOR 💬 51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬1件: 13 💬
50 Tenofovir 💬1件: Tenofovir1件: Tenofovir--6件: 2, 13, 25, 93, 265, 325 💬
51 Teriparatide 💬1件: Teriparatide4件: Forsteo; Forteo; PTH 1-34; Teriparatide1件: PTH1R 💬 3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬7件: 46, 65, 68, 70, 71, 235, 274 💬
52 Testosterone undecanoate 💬1件: Testosterone undecanoate1件: Testosterone undecanoate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 13, 60 💬
53 Theophylline 💬1件: Theophylline1件: Theophylline18件: ADORA1,
ADORA2B,
PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		23件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 236, 299 💬
54 Thymalfasin 💬1件: Thymalfasin1件: THYMALFASIN--1件: 65 💬
55 Tocophersolan 💬1件: Tocofersolan1件: VEDROP--1件: 299 💬
56 Toralizumab 💬1件: Toralizumab1件: Anti-CD40L1件: CD40LG 💬 14件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, T cell receptor signaling pathway, Toxoplasmosis, Viral myocarditis 💬1件: 63 💬
57 Trabectedin 💬1件: Trabectedin2件: TRABECTEDINA; Yondelis--1件: 159 💬
58 Treprostinil 💬1件: Treprostinil4件: Remodulin; Treprostinil; Treprostinilo; Tyvaso1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬6件: 51, 84, 85, 86, 88, 210 💬
59 Triptorelin 💬1件: Triptorelin2件: GnRH; Triptorelin1件: GNRHR 💬 2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬2件: 49, 76 💬
60 Tafluprost 💬1件: Tafluprost1件: TAFLUPROST1件: PTGFR 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 299 💬
61 Thrombomodulin alfa 💬1件: Thrombomodulin Alfa1件: Thrombomodulin Alfa1件: F2 💬 8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬1件: 85 💬
62 Tesamorelin 💬1件: Tesamorelin2件: GHRH; Tesamorelin1件: GHRHR 💬 2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 78, 265 💬
63 Tremelimumab 💬1件: Tremelimumab1件: Ticilimumab1件: CTLA4 💬 4件: Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬1件: 96 💬
64 Tipelukast 💬1件: Tipelukast1件: Tipelukast1件: CYSLTR1 💬 2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 85 💬
65 Terlipressin 💬1件: Terlipressin1件: TERLIPRESSIN3件: AVPR1A,
AVPR1B,
AVPR2 💬 		5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬1件: 299 💬
66 Tiratricol 💬1件: Tiratricol1件: Tiratricol2件: THRA,
THRB 💬 		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬2件: 78, 139 💬
67 Treosulfan 💬1件: Treosulfan2件: OVASTAT; Treosulfan--6件: 13, 19, 62, 65, 283, 286 💬
68 Tacrine 💬1件: Tacrine0件: 1件: ACHE 💬 2件: Cholinergic synapse, Glycerophospholipid metabolism 💬-
69 Tacrolimus 💬1件: Tacrolimus2件: Prograf; Tacrolimus5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬34件: 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
70 Tamoxifen 💬1件: Tamoxifen2件: TAMOXIFEN; TAMOXIFEN CITRATE2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬3件: 2, 113, 227 💬
71 Tamsulosin 💬1件: Tamsulosin1件: Tamsulosin3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13 💬
72 Terazosin 💬1件: Terazosin1件: Terazosin3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 6 💬
73 Terbutaline 💬1件: Terbutaline1件: Terbutaline1件: ADRB2 💬 9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 118 💬
74 Testosterone decanoate 💬1件: Testosterone decanoate1件: Testosterone decanoate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
75 Testosterone phenylpropionate 💬1件: Testosterone phenylpropionate1件: Testosterone phenylpropionate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 113 💬
76 Tetrabenazine 💬1件: Tetrabenazine2件: Tetrabenazine; Xenazine1件: SLC18A2 💬 7件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 8 💬
77 Thiamine 💬1件: Thiamine2件: THIAMINE; Vitamin B1--4件: 8, 93, 145, 265 💬
78 Tiapride 💬1件: Tiapride0件: 1件: DRD2 💬 8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬-
79 Ticarcillin 💬1件: Ticarcillin1件: Ticarcillin--1件: 299 💬
80 Timolol 💬1件: Timolol2件: Timolol; TIMOLOL MALEATE2件: ADRB1,
ADRB2 💬 		11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 157, 227 💬
81 Tioguanine 💬1件: Tioguanine0件: 1件: HPRT1 💬 4件: Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬-
82 Tipranavir 💬1件: Tipranavir1件: Tipranavir--1件: 265 💬
83 Tizanidine 💬1件: Tizanidine1件: Tizanidine3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬1件: 13 💬
84 Tolperisone 💬1件: Tolperisone1件: Tolperisone--1件: 13 💬
85 Topotecan 💬1件: Topotecan1件: Topotecan1件: TOP1 💬 1件: 💬1件: 25 💬
86 Tramadol 💬1件: Tramadol2件: Tramadol; Ultracet1件: OPRM1 💬 3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271 💬
87 Trazodone 💬1件: Trazodone1件: Trazodone4件: HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬 		6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 2 💬
88 Trifluoperazine 💬1件: Trifluoperazine1件: Trifluoperazine1件: DRD2 💬 8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 283, 284 💬
89 Trihexyphenidyl 💬1件: Trihexyphenidyl1件: Trihexyphenidyl5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 5, 6 💬
90 Trimebutine 💬1件: Trimebutine1件: Trimebutine2件: OPRK1,
OPRM1 💬 		3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 51 💬
91 Trimetazidine 💬1件: Trimetazidine1件: Trimetazidine--3件: 2, 58, 86 💬
92 Trimethobenzamide 💬1件: Trimethobenzamide3件: Tigan; Trimethobenzamide; Trimethobenzamide Hydrochloride--1件: 6 💬
93 Tarenflurbil 💬1件: Tarenflurbil2件: FLURBIPROFEN; Tarenflurbil4件: APH1A,
NCSTN,
PSEN1,
PSENEN 💬 		6件: Alzheimer disease, Human papillomavirus infection, Neurotrophin signaling pathway, Notch signaling pathway, Pathways of neurodegeneration - multiple diseases, Wnt signaling pathway 💬1件: 13 💬
94 Ticagrelor 💬1件: Ticagrelor1件: Ticagrelor1件: P2RY12 💬 1件: Platelet activation 💬1件: 46 💬
95 Tanezumab 💬1件: Tanezumab1件: Tanezumab1件: NGF 💬 9件: Apoptosis, Calcium signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬2件: 226, 298 💬
96 Tasimelteon 💬1件: Tasimelteon1件: Tasimelteon2件: MTNR1A,
MTNR1B 💬 		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬1件: 202 💬
97 Tafamidis 💬1件: Tafamidis2件: Tafamidis; Vyndaqel1件: TTR 💬 1件: Thyroid hormone synthesis 💬1件: 28 💬
98 Taliglucerase alfa 💬1件: Taliglucerase alfa3件: Elelyso; PrGCD; TALIGLUCERASE ALFA1件: GBA1 💬 4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
99 Teprotumumab 💬1件: Teprotumumab1件: TEPEZZA1件: IGF1R 💬 29件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, HIF-1 signaling pathway, Hepatocellular carcinoma, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬1件: 51 💬
100 Tedizolid 💬1件: Tedizolid1件: Tedizolid--1件: 299 💬
101 Tofacitinib 💬1件: Tofacitinib4件: Tasocitinib; TOFACITINIB; XELJANZ; Xeljanz XR4件: JAK1,
JAK2,
JAK3,
TYK2 💬 		37件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
102 Telotristat 💬1件: Telotristat1件: Telotristat2件: TPH1,
TPH2 💬 		4件: Folate biosynthesis, Metabolic pathways, Serotonergic synapse, Tryptophan metabolism 💬1件: 97 💬
103 Tralokinumab 💬1件: Tralokinumab1件: Tralokinumab1件: IL13 💬 8件: Asthma, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, IL-17 signaling pathway, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation 💬2件: 85, 97 💬
104 Tabalumab 💬1件: Tabalumab1件: TABALUMAB1件: TNFSF13B 💬 4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬2件: 46, 49 💬
105 Teriflunomide 💬1件: Teriflunomide2件: AUBAGIO; Teriflunomide1件: DHODH 💬 3件: Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬3件: 13, 25, 26 💬
106 Tozadenant 💬1件: Tozadenant1件: TOZADENANT1件: ADORA2A 💬 7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6 💬
107 Trametinib 💬1件: Trametinib2件: Mekinist; Trametinib2件: MAP2K1,
MAP2K2 💬 		89件: Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬4件: 2, 34, 279, 280 💬
108 Tirasemtiv 💬1件: Tirasemtiv1件: Tirasemtiv--1件: 2 💬
109 Tildrakizumab 💬1件: Tildrakizumab2件: Ilumetri; Tildrakizumab1件: IL23A 💬 9件: C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬2件: 162, 271 💬
110 Tenofovir alafenamide 💬1件: Tenofovir alafenamide1件: Tenofovir alafenamide--2件: 2, 13 💬
111 Taladegib 💬1件: Taladegib1件: Taladegib1件: SMO 💬 5件: Axon guidance, Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, Proteoglycans in cancer 💬1件: 85 💬
112 Tezacaftor 💬1件: Tezacaftor5件: Kaftrio; Symdeko; Symkevi; TEZACAFTOR; Trikafta1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299 💬
113 Tibulizumab 💬1件: Tibulizumab1件: Tibulizumab2件: IL17A,
TNFSF13B 💬 		8件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis, Th17 cell differentiation 💬1件: 53 💬
114 Tabelecleucel 💬1件: Tabelecleucel1件: Tabelecleucel--1件: 65 💬
115 Taldefgrobep alfa 💬1件: Talditercept alfa1件: Taldefgrobep alfa1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
116 Tirzepatide 💬1件: Tirzepatide1件: Tirzepatide2件: GIPR,
GLP1R 💬 		3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 233 💬
117 Tavapadon 💬1件: Tavapadon2件: PF-06649751; TAVAPADON2件: DRD1,
DRD5 💬 		10件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬1件: 6 💬
118 Triheptanoin 💬1件: Triheptanoin1件: Triheptanoin--10件: 2, 8, 65, 149, 156, 248, 256, 257, 317, 324 💬
119 Tropifexor 💬1件: Tropifexor1件: Tropifexor1件: NR1H4 💬 1件: Bile secretion 💬1件: 93 💬
120 Tezepelumab 💬1件: Tezepelumab3件: AMG 157; MEDI9929; Tezepelumab1件: TSLP 💬 2件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬1件: 98 💬
121 Tesevatinib 💬1件: Tesevatinib1件: Tesevatinib5件: EGFR,
EPHB4,
ERBB2,
FLT4,
KDR 💬 		53件: Adherens junction, Axon guidance, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction, VEGF signaling pathway 💬1件: 67 💬
122 Tofersen 💬1件: Tofersen1件: Tofersen1件: SOD1 💬 8件: Amyotrophic lateral sclerosis, Chemical carcinogenesis - reactive oxygen species, Huntington disease, Longevity regulating pathway - multiple species, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Peroxisome, Prion disease 💬1件: 2 💬
123 Taurursodiol 💬1件: Tauroursodeoxycholic acid4件: TAUROURSODEOXYCHOLIC ACID; Taurursodiol; TUDCA; Ursodoxicoltaurine--3件: 2, 93, 299 💬
124 Tozinameran 💬1件: Tozinameran2件: Comirnaty; Tozinameran--5件: 13, 46, 51, 53, 299 💬
125 Trofinetide 💬1件: Trofinetide1件: Trofinetide--1件: 156 💬