Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Alginic acid 💬1件: Alginic acid (Norgine)4件: Algin; Alginate; Alginic acid; Sodium alginate--4件: 51, 53, 97, 299 💬
2 Amlodipine 💬
(Norvasc (TN))		1件: Amlodipine1件: Amlodipine4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 67, 298 💬
3 Amlodipine besylate 💬
(Norvasc (TN), NORLIQVA, NORVASC)		1件: Amlodipine1件: Amlodipine4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 67, 298 💬
4 Capsaicin 💬1件: Capsaicin (trans-8-Methyl-N-vanillyl-6-nonenamide)1件: Capsaicin1件: TRPV1 💬 2件: Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 2, 6, 86, 226 💬
5 Catridecacog 💬
(NovoThirteen (TN))		1件: Catridecacog1件: Catridecacog--2件: 97, 288 💬
6 Chlorhexidine acetate 💬
(Nolvasan (TN))		1件: Chlorhexidine2件: Chlorhexidine; Chlorhexidine gluconate--2件: 86, 299 💬
7 Cyanocobalamin 💬1件: Cyanocobalamin (Vitamin B12 NOS)2件: Cianocobalamina; Vitamin B12--3件: 6, 13, 201 💬
8 Cyanocobalamin Co 57 💬1件: Cyanocobalamin (Vitamin B12 NOS)2件: Cianocobalamina; Vitamin B12--3件: 6, 13, 201 💬
9 Cyanocobalamin Co 58 💬1件: Cyanocobalamin (Vitamin B12 NOS)2件: Cianocobalamina; Vitamin B12--3件: 6, 13, 201 💬
10 Cyanocobalamin Co 60 💬1件: Cyanocobalamin (Vitamin B12 NOS)2件: Cianocobalamina; Vitamin B12--3件: 6, 13, 201 💬
11 Desipramine 💬1件: Desipramine (Norimipramine)1件: Desipramine2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 121 💬
12 Desipramine hydrochloride 💬
(Norpramin (TN))		1件: Desipramine (Norimipramine)1件: Desipramine2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬1件: 121 💬
13 Droxidopa 💬
(Northera (TN), NORTHERA)		1件: Droxidopa2件: Droxidopa; L-dops9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170 💬
14 Duvoglustat 💬1件: Duvoglustat (1-deoxy-nojirimycin)2件: Duvoglustat; Duvoglustat hydrochloride1件: GAA 💬 3件: Galactose metabolism, Lysosome, Starch and sucrose metabolism 💬1件: 256 💬
15 Duvoglustat hydrochloride 💬1件: Duvoglustat (1-deoxy-nojirimycin)2件: Duvoglustat; Duvoglustat hydrochloride1件: GAA 💬 3件: Galactose metabolism, Lysosome, Starch and sucrose metabolism 💬1件: 256 💬
16 Edaravone 💬1件: Edaravone (Norphenazone)3件: Edaravone; Methylphenylpyrazolone; Norphenazone--3件: 2, 6, 22 💬
17 Eptacog alfa 💬
(Novo- seven (TN))		1件: Coagulation factor VIIa Recombinant Human0件: 1件: F7 💬 1件: Complement and coagulation cascades 💬-
18 Gallium nitrate 💬1件: Gallium nitrate (Gallium nitrate nonahydrate)1件: Gallium nitrate--1件: 299 💬
19 Globulin, immune 💬
(Human normal immunoglobulin (JP18))		1件: Human immunoglobulin G (Human normal immunoglobulin)6件: Human immunoglobulin G; Human normal immunoglobulin; Immune globulin; Immunoglobulin; Immunoglobulin G; Intravenous immunoglobulin--9件: 11, 13, 14, 43, 45, 50, 51, 63, 65 💬
20 Green tea leaf 💬1件: Green tea leaf (Camelliae Sinensis Non Fermentatum Folium)3件: Green TEA; Green TEA leaf; TEA extract--4件: 6, 17, 28, 96 💬
21 Hemin 💬
(Normosang (TN))		1件: Hemin1件: Hemin2件: E2.3.1.37,
E2.3.1.37 💬 		2件: Glycine, serine and threonine metabolism, Porphyrin metabolism 💬1件: 254 💬
22 Istradefylline 💬
(Nourianz (TN), Nouriast (TN), NOURIANZ)		1件: Istradefylline1件: Istradefylline1件: ADORA2A 💬 8件: Alcoholism, Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6 💬
23 Laureth 4 💬1件: Polidocanol (Nonaethylene glycol monododecyl ether)1件: Polidocanol--3件: 34, 278, 279 💬
24 Levobupivacaine 💬
(Novabupi (TN))		1件: Levobupivacaine1件: Levobupivacaine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 46 💬
25 Levonorgestrel 💬
(Norplant (TN))		1件: Levonorgestrel (17-Ethynyl-18-methyl-19-nortestosterone)1件: Levonorgestrel1件: PGR 💬 5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13 💬
26 Lysine 💬1件: Lysine (6-ammonio-L-norleucine)1件: Lysine--1件: 228 💬
27 Lysine acetate 💬1件: Lysine (6-ammonio-L-norleucine)1件: Lysine--1件: 228 💬
28 Lysine hydrochloride 💬1件: Lysine (6-ammonio-L-norleucine)1件: Lysine--1件: 228 💬
29 Lysine hydrochloride 💬1件: Lysine (6-ammonio-L-norleucine)1件: Lysine--1件: 228 💬
30 Metronidazole 💬
(Noritate (TN), NORITATE)		1件: Metronidazole2件: Metronidazol; Metronidazole--7件: 46, 51, 63, 94, 96, 97, 291 💬
31 Mitoxantrone hydrochloride 💬
(Novantron (TN))		1件: Mitoxantrone1件: Mitoxantrone--1件: 13 💬
32 Nandrolone 💬1件: Nandrolone (19-nortestosterone)1件: Nandrolone1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬1件: 60 💬
33 Nandrolone decanoate 💬1件: Nandrolone decanoate (19-nortestosterone decanoate)1件: Nandrolone decanoate1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 60, 85 💬
34 Nitric oxide 💬
(NOXIVENT 101, NOXIVENT 102)		1件: Nitric Oxide1件: Nitric oxide--8件: 51, 85, 86, 88, 97, 210, 294, 299 💬
35 Nomacopan 💬
(Nomacopan (USAN/INN))		1件: Nomacopan (Nomacopan)2件: Coversin; Nomacopan1件: C5 💬 11件: Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬3件: 62, 109, 162 💬
36 Nomegestrol 💬
(Nomegestrol (USAN/INN))		1件: Nomegestrol (Nomegestrol)1件: Nomegestrol1件: PGR 💬 5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13 💬
37 Nomegestrol acetate 💬
(Nomegestrol acetate (USAN))		1件: Nomegestrol acetate (Nomegestrol acetate)1件: Nomegestrol acetate1件: PGR 💬 5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 13 💬
38 Noradrenaline 💬
(Noradrenaline (JP18), Norepinephrine (INN), Nor adrenalin (TN))		1件: Norepinephrine (Norepinephrine bitartrate)2件: Norepinephrine; Norepinephrine bitartrate9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 22, 296 💬
39 Norepinephrine bitartrate 💬
(Norepinephrine bitartrate (USP), LEVOPHED(R) NOREPINEPHRINE BITARTRATE, NOREPINEPHRINE, NOREPINEPHRINE BITARTRATE, NOREPINEPHRINE BITARTRATE IN SODIUM CHLORIDE, NOREPINEPHR BITART)		1件: Norepinephrine (Norepinephrine bitartrate)2件: Norepinephrine; Norepinephrine bitartrate9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 22, 296 💬
40 Norepinephrine hydrochoride 💬
(Norepinephrine hydrochoride, (-)-Noradrenaline hydrochloride)		1件: Norepinephrine (Norepinephrine bitartrate)2件: Norepinephrine; Norepinephrine bitartrate9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		16件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 22, 296 💬
41 Norethindrone 💬
(Norethindrone (USP), Norethisterone (JP18))		1件: Norethisterone (19-nor-17α-ethynyl-17β-hydroxy-4-androsten-3-one)1件: Norethindrone1件: PGR 💬 5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬4件: 13, 46, 49, 299 💬
42 Norethindrone acetate 💬
(Norethindrone acetate (USP), Norethisterone acetate (JAN))		1件: Norethisterone (19-nor-17α-ethynyl-17β-hydroxy-4-androsten-3-one)1件: Norethindrone1件: PGR 💬 5件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬4件: 13, 46, 49, 299 💬
43 Nortriptyline 💬
(Nortriptyline (INN), Nortrilen (TN))		1件: Nortriptyline (Nortriptylinum)2件: Nortriptyline; Nortriptyline hydrochloride2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226 💬
44 Nortriptyline hydrochloride 💬
(Nortriptyline hydrochloride (JP18/USP/INN), NORTRIPTYLINE HCL, NORTRIPTYLINE HYDROCHLORIDE)		1件: Nortriptyline (Nortriptylinum)2件: Nortriptyline; Nortriptyline hydrochloride2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 226 💬
45 Panax notoginseng root 💬
(Panax notoginseng root (Non-JPS), Powdered panax notoginseng root (Non-JPS), Panacis notoginseng radix)		1件: Panax notoginseng root (Panax Pseudoginseng Notoginseng)1件: Sanqi--2件: 222, 224 💬
46 Polidocanol 💬1件: Polidocanol (Nonaethylene glycol monododecyl ether)1件: Polidocanol--3件: 34, 278, 279 💬
47 Posaconazole 💬
(Noxafil (TN), NOXAFIL)		1件: Posaconazole1件: Posaconazole--3件: 60, 65, 299 💬
48 Quetiapine 💬
(Norsic (TN))		1件: Quetiapine1件: Quetiapine2件: DRD2,
HTR2 💬 		13件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬1件: 6 💬
49 Rifampin 💬
(RIFADIN IV NOVAPLUS)		1件: Rifampin2件: Rifampicin; Rifampin--10件: 6, 13, 17, 46, 84, 86, 93, 97, 299, 338 💬
50 Ritonavir 💬
(Norvir (TN), NORVIR)		1件: Ritonavir1件: Ritonavir--3件: 2, 86, 265 💬
51 Rozanolixizumab 💬
(rozanolixizumab-noli)		1件: Rozanolixizumab2件: Rozanolixizumab; UCB7665--3件: 11, 14, 63 💬
52 Scopolamine 💬1件: Scopolamine (alpha-non-7-yl ester)1件: Scopolamine5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 2 💬
53 Sodium alginate 💬1件: Alginic acid (Norgine)4件: Algin; Alginate; Alginic acid; Sodium alginate--4件: 51, 53, 97, 299 💬
54 Somatropin 💬
(NORDITROPIN)		1件: Somatotropin7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬26件: 2, 3, 19, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
55 Tamoxifen citrate 💬
(Nolvadex (TN))		1件: Tamoxifen2件: Tamoxifen; Tamoxifen citrate2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬4件: 2, 86, 113, 227 💬
56 Topotecan hydrochloride 💬
(Nogitecan hydrochloride (JAN))		1件: Topotecan1件: Topotecan--1件: 25 💬
57 Vitamin B12 💬1件: Cyanocobalamin (Vitamin B12 NOS)2件: Cianocobalamina; Vitamin B12--3件: 6, 13, 201 💬