Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 S1PR1 💬 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬
2 FCGRT 💬 - Nipocalimab 💬 Nipocalimab 6件: 11, 14, 46, 49, 53, 61 💬
3 FCGRT 💬 - Efgartigimod alfa 💬 Efgartigimod alfa 6件: 11, 14, 35, 53, 63, 162 💬
4 FCGRT 💬 - Batoclimab 💬 Batoclimab 2件: 11, 14 💬
5 FCGRT 💬 - Rozanolixizumab 💬 Rozanolixizumab 3件: 11, 14, 63 💬
6 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
7 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone 46件: 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
8 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
9 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
10 HRH1 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels Chlorphenamine 💬 Chlorpheniramine 1件: 14 💬
11 KCNA4 💬 2件: Cortisol synthesis and secretion, Cushing syndrome Dalfampridine 💬 Dalfampridine 5件: 3, 4, 6, 13, 14 💬
12 KCNC3 💬 1件: Spinocerebellar ataxia Dalfampridine 💬 Dalfampridine 5件: 3, 4, 6, 13, 14 💬
13 KCND2 💬 1件: Serotonergic synapse Dalfampridine 💬 Dalfampridine 5件: 3, 4, 6, 13, 14 💬
14 KCND3 💬 1件: Spinocerebellar ataxia Dalfampridine 💬 Dalfampridine 5件: 3, 4, 6, 13, 14 💬
15 MC2R 💬 5件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome Corticotropin 💬 Corticotropin 12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
16 TOP2A 💬 1件: Platinum drug resistance Etoposide 💬 Etoposide 11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
17 TOP2B 💬 1件: Platinum drug resistance Etoposide 💬 Etoposide 11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
18 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Eculizumab 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬
19 MS4A1 💬 1件: Hematopoietic cell lineage Rituximab 💬 Rituximab 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬