Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
6 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
7 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
8 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
9 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A 1件: SCN5A 💬 |
Lidocaine Lidocaine 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
10 | Adrenergic signaling in cardiomyocytes 💬 27 genes, 80 drugs (DrugBank) and 71 diseases |
SCN5A 1件: SCN5A 💬 |
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
11 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
12 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
13 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
14 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
15 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
16 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
17 | African trypanosomiasis 💬 9 genes, 22 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
18 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
19 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
20 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
21 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
22 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
23 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
24 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
25 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
26 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
27 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
28 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
29 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
30 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
31 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
32 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
33 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
34 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
35 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
36 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL10 2件: IL10, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
37 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
38 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
39 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
40 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
41 | Allograft rejection 💬 11 genes, 23 drugs (DrugBank) and 56 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
42 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
CHRNA7 1件: CHRNA7 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
43 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
44 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
45 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
46 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
47 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
48 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
49 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
50 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
51 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
52 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
53 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
54 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
55 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
56 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
57 | Amoebiasis 💬 19 genes, 29 drugs (DrugBank) and 63 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
58 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
59 | Amphetamine addiction 💬 25 genes, 51 drugs (DrugBank) and 91 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
60 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
61 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
62 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
63 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
64 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
65 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
66 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
67 | Amyotrophic lateral sclerosis 💬 35 genes, 48 drugs (DrugBank) and 108 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
68 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
69 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
70 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
71 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
72 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
73 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
74 | Antifolate resistance 💬 8 genes, 21 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
75 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
76 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
77 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
78 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
79 | Antigen processing and presentation 💬 4 genes, 15 drugs (DrugBank) and 52 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
80 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
81 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
82 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
83 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
84 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
85 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
86 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
IL10 2件: IL10, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
87 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
88 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
89 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
90 | Asthma 💬 8 genes, 22 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
91 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
92 | Autoimmune thyroid disease 💬 22 genes, 15 drugs (DrugBank) and 35 diseases |
IL10 1件: IL10 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
93 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
94 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
95 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
96 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
NR1H4 1件: NR1H4 💬 |
Ursodiol Ursodiol 💬 |
Ursodeoxycholic acid | 006 14件: 6 , 8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬 💬 |
97 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 51 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
98 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
99 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL10 4件: IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
100 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
101 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
102 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
103 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
104 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
105 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
106 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
CHRNA7 1件: CHRNA7 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
107 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
108 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
109 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
110 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
111 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
112 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
113 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
114 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 💬 |
115 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
SSTR2 1件: SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 💬 |
116 | Cell adhesion molecules 💬 14 genes, 22 drugs (DrugBank) and 35 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
117 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
118 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
119 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
120 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
121 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
122 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
123 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
124 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
PDE5A 1件: PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
125 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
126 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
127 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
128 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
129 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
130 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
131 | Chagas disease 💬 28 genes, 44 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
132 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
CHRNA3 6件: CHRNA3, CHRNA4, CHRNA7, CHRNA9, CHRNB2, CHRNB4 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
133 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
134 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
135 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR 1件: VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
136 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
VDR 1件: VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 💬 |
137 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCL2 1件: CCL2 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
138 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
139 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 2件: JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
140 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
141 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
CHRNA3 6件: CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
142 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
143 | Circadian entrainment 💬 22 genes, 32 drugs (DrugBank) and 55 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
144 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
145 | Cocaine addiction 💬 15 genes, 63 drugs (DrugBank) and 52 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
146 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
147 | Complement and coagulation cascades 💬 17 genes, 29 drugs (DrugBank) and 44 diseases |
SERPINC1 1件: SERPINC1 💬 |
Adomiparin Adomiparin 💬 |
Heparin | 047 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬 💬 |
148 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
149 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
150 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
151 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
152 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
153 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
154 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
155 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
156 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
157 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
158 | Cortisol synthesis and secretion 💬 15 genes, 33 drugs (DrugBank) and 61 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
159 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
160 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 6件: CCL2, IL10, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
161 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
162 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
163 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
164 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
165 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
166 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
167 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
168 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
169 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
170 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
171 | Cytosolic DNA-sensing pathway 💬 17 genes, 12 drugs (DrugBank) and 28 diseases |
IL1B 2件: IL1B, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
172 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
173 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
174 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
175 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
176 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
177 | Dilated cardiomyopathy 💬 17 genes, 55 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
178 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A 1件: SCN1A 💬 |
Lidocaine Lidocaine 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
179 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SCN1A 1件: SCN1A 💬 |
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
180 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
181 | Dopaminergic synapse 💬 31 genes, 99 drugs (DrugBank) and 101 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
182 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 48 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
183 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6 1件: IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
184 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
185 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
186 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
187 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
188 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
189 | Endocrine and other factor-regulated calcium reabsorption 💬 8 genes, 27 drugs (DrugBank) and 55 diseases |
VDR 1件: VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 💬 |
190 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
191 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
192 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
IL6 2件: IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
193 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
194 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
195 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
196 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
197 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
198 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
199 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
200 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
201 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
202 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
203 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
204 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
205 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
CCL2 4件: CCL2, IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
206 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
207 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
208 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
209 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
210 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
211 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
212 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 39 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
213 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IL10 2件: IL10, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
214 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
215 | Gastric acid secretion 💬 14 genes, 43 drugs (DrugBank) and 52 diseases |
SSTR2 1件: SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 💬 |
216 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
217 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
218 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
219 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
220 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
221 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
222 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
223 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
224 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
225 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
226 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
227 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
SSTR2 1件: SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 💬 |
228 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
229 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
230 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
231 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
232 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
MS4A1 1件: MS4A1 💬 |
Rituximab Rituximab 💬 |
Rituximab | 011 48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 💬 |
233 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
234 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
235 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
236 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
237 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
IL6 2件: IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
238 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
239 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
240 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
241 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
242 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
243 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
244 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
245 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 2件: JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
246 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
247 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
248 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
249 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
250 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
251 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
252 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
253 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
254 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
255 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
256 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
257 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
258 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
259 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
260 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
261 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
262 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6 1件: IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
263 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
264 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
265 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
266 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
267 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
268 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
269 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
270 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
271 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
272 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
273 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
274 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
275 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
276 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
277 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
278 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
279 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
280 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
281 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
282 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
283 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
284 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
285 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 2件: JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
286 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
287 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
288 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
289 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
290 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
291 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
292 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
293 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
IL6 2件: IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
294 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
295 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 2件: JAK1, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
296 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
297 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
298 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
299 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
300 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
301 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
IL6 2件: IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
302 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
303 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
304 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
305 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
306 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
307 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
308 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
309 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
310 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
311 | IL-17 signaling pathway 💬 20 genes, 60 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
312 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
313 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
314 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
315 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
316 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
317 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
318 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
319 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
320 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1B 1件: IL1B 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
321 | Inflammatory mediator regulation of TRP channels 💬 23 genes, 43 drugs (DrugBank) and 59 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
322 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
323 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
324 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
325 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
326 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
327 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
328 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
329 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
330 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
331 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
IL6 2件: IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
332 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
333 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
334 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
335 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
336 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
337 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
338 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
339 | Intestinal immune network for IgA production 💬 16 genes, 27 drugs (DrugBank) and 47 diseases |
IL10 2件: IL10, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
340 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL10 2件: IL10, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
341 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
342 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
343 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
344 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
345 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
346 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
347 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
CD86 1件: CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
348 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
IL6 1件: IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
349 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
350 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
351 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
352 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
353 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
354 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
355 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
356 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
357 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
358 | Legionellosis 💬 9 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
359 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL10 4件: IL10, IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
360 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
361 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
362 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
363 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
364 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
365 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
366 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
367 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
368 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
369 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
370 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
371 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
372 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
373 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
374 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
375 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
376 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
377 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
378 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
379 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
380 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL12A 1件: IL12A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
381 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
382 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
383 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
384 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
385 | Malaria 💬 15 genes, 28 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
386 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
387 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
388 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
389 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
390 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
391 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
392 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
393 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
394 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A 3件: IL1A, IL1B, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
395 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
396 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
397 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
398 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB 1件: EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
399 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
EDNRB 1件: EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
400 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
401 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
402 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
403 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
404 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 💬 |
405 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE5A 1件: PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
406 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
407 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR 1件: VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
408 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 41 diseases |
VDR 1件: VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 💬 |
409 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 💬 |
410 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
411 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
412 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
413 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
414 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
415 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
416 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
417 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
418 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
419 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
420 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
421 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
422 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
423 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
424 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
425 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
426 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
427 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
428 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
429 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
CHRNA1 16件: CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
430 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
431 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
432 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
433 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC2R 1件: MC2R 💬 |
Corticotropin Corticotropin 💬 |
Corticotropin | 002 12件: 2 , 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬 💬 |
434 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Ciclesonide Ciclesonide 💬 |
Ciclesonide | 084 1件: 84 💬 💬 |
435 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Dexamethasone Dexamethasone 💬 |
Dexamethasone | 013 22件: 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬 💬 |
436 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Methylprednisolone Methylprednisolone 💬 |
Methylprednisolone | 002 46件: 2 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 💬 |
437 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Prednisolone Prednisolone 💬 |
Prednisolone | 003 42件: 3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 💬 |
438 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
NR3C1 1件: NR3C1 💬 |
Prednisone Prednisone 💬 |
Prednisone | 002 45件: 2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬 💬 |
439 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR 1件: PTGIR 💬 |
Iloprost Iloprost 💬 |
Iloprost | 051 4件: 51, 84, 85, 86 💬 💬 |
440 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR 1件: PTGIR 💬 |
Selexipag Selexipag 💬 |
Selexipag | 051 5件: 51, 70, 84, 86, 88 💬 💬 |
441 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
PTGIR 1件: PTGIR 💬 |
Treprostinil Treprostinil 💬 |
Treprostinil | 051 6件: 51, 84, 85, 86, 88, 210 💬 💬 |
442 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
SSTR2 1件: SSTR2 💬 |
Octreotide Octreotide 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 💬 |
443 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
444 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
445 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 2件: IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
446 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
447 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
448 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
449 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
450 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
451 | Nicotine addiction 💬 30 genes, 30 drugs (DrugBank) and 44 diseases |
CHRNA4 4件: CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
452 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
453 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
454 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
455 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 2件: JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
456 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
457 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
458 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
459 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
460 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
461 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
462 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
463 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
464 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
465 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
466 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
467 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
JAK3 1件: JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
468 | Nucleotide metabolism 💬 7 genes, 12 drugs (DrugBank) and 46 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
469 | One carbon pool by folate 💬 3 genes, 2 drugs (DrugBank) and 38 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
Methotrexate Methotrexate 💬 |
Methotrexate | 011 38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬 💬 |
470 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
471 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
472 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
473 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
474 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
475 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
476 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
477 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
478 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
479 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
480 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
481 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
482 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
483 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 💬 |
484 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR 1件: VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
485 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
VDR 1件: VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 💬 |
486 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
487 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
488 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
489 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
490 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
491 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
492 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
493 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
494 | Pathogenic Escherichia coli infection 💬 26 genes, 39 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
495 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
496 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
497 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
498 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
499 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6 1件: IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
500 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
501 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
502 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
503 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
504 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
CHRNA7 1件: CHRNA7 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
505 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
506 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
507 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
508 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
509 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
SLC6A3 1件: SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
510 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
511 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
512 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
513 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
514 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
515 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
516 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
517 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
518 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
519 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
520 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
521 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
522 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
523 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
524 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
525 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6 1件: IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
526 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
527 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
528 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
529 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
530 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
531 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR 1件: PTGIR 💬 |
Iloprost Iloprost 💬 |
Iloprost | 051 4件: 51, 84, 85, 86 💬 💬 |
532 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR 1件: PTGIR 💬 |
Selexipag Selexipag 💬 |
Selexipag | 051 5件: 51, 70, 84, 86, 88 💬 💬 |
533 | Platelet activation 💬 22 genes, 51 drugs (DrugBank) and 56 diseases |
PTGIR 1件: PTGIR 💬 |
Treprostinil Treprostinil 💬 |
Treprostinil | 051 6件: 51, 84, 85, 86, 88, 210 💬 💬 |
534 | Primary immunodeficiency 💬 11 genes, 23 drugs (DrugBank) and 26 diseases |
JAK3 1件: JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
535 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
536 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
537 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
538 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
539 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
540 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
541 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 1件: JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
542 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IL1R2 1件: IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
543 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
544 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IL12B 1件: IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
545 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
546 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
547 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
548 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
549 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
550 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
551 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
552 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
IMPDH1 2件: IMPDH1, IMPDH2 💬 |
Mycophenolic acid Mycophenolic acid 💬 |
Mycophenolic acid | 002 36件: 2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬 💬 |
553 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Roflumilast Roflumilast 💬 |
Roflumilast | 084 4件: 84, 97, 206, 299 💬 💬 |
554 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE5A 1件: PDE5A 💬 |
Tadalafil Tadalafil 💬 |
Tadalafil | 006 7件: 6 , 51, 75, 84, 86, 113, 210 💬 💬 |
555 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
556 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
557 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
558 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
559 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
560 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
561 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
562 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
563 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
564 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL23A 1件: IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
565 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
566 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
567 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
568 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
569 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
570 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
571 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
572 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
573 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
574 | RIG-I-like receptor signaling pathway 💬 22 genes, 18 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
575 | Salivary secretion 💬 19 genes, 61 drugs (DrugBank) and 56 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
576 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
577 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
578 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
579 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
580 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
581 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
582 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
583 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1B 2件: IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
584 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
585 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
586 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
587 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
588 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
589 | Shigellosis 💬 23 genes, 41 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
590 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
591 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
592 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
593 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
594 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
595 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
596 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
597 | Spinocerebellar ataxia 💬 17 genes, 25 drugs (DrugBank) and 70 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
598 | Staphylococcus aureus infection 💬 12 genes, 19 drugs (DrugBank) and 34 diseases |
IL10 1件: IL10 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
599 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A2 2件: SLC6A2, SLC6A3 💬 |
Methylphenidate Methylphenidate 💬 |
Methylphenidate | 006 7件: 6 , 13, 34, 84, 113, 179, 206 💬 💬 |
600 | Synaptic vesicle cycle 💬 7 genes, 30 drugs (DrugBank) and 40 diseases |
SLC6A3 1件: SLC6A3 💬 |
Armodafinil Armodafinil 💬 |
Armodafinil | 006 3件: 6 , 13, 84 💬 💬 |
601 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
602 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
IL10 2件: IL10, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
603 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
604 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
605 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
606 | Systemic lupus erythematosus 💬 14 genes, 38 drugs (DrugBank) and 78 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
607 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
IL10 2件: IL10, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
608 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
609 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
610 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
611 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
612 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A 3件: SCN2A, SCN3A, SCN9A 💬 |
Lidocaine Lidocaine 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
613 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
SCN2A 3件: SCN2A, SCN3A, SCN9A 💬 |
Lidocaine hydrochloride monohydrate Lidocaine hydrochloride monohydrate 💬 |
Lidocaine | 006 13件: 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬 💬 |
614 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
615 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
616 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
617 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
618 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
619 | TGF-beta signaling pathway 💬 10 genes, 20 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
620 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
621 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
622 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
623 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
624 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 2件: IL1B, IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
625 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
626 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
627 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
628 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
629 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
630 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
631 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
632 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
633 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
CCL2 4件: CCL2, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
634 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
635 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
636 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
637 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
638 | TNF signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
639 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
640 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
641 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
642 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
IL1B 3件: IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
643 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
644 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
645 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
646 | Toll-like receptor signaling pathway 💬 36 genes, 46 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
647 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
648 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL10 2件: IL10, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
649 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
650 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
651 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
652 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
653 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
654 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
655 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
656 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
CD86 1件: CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
657 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL1R2 1件: IL1R2 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
658 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IL6 1件: IL6 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
659 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
660 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL12A 3件: IL12A, IL12B, IL23A 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
661 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
662 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
663 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
664 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
665 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
666 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
667 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
668 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR 1件: VDR 💬 |
Cholecalciferol Cholecalciferol 💬 |
Cholecalciferol | 006 24件: 6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬 💬 |
669 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
VDR 1件: VDR 💬 |
Ergocalciferol Ergocalciferol 💬 |
Ergocalciferol | 046 6件: 46, 49, 84, 96, 97, 299 💬 💬 |
670 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
671 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL12A 2件: IL12A, IL12B 💬 |
Ustekinumab Ustekinumab 💬 |
Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬 💬 |
672 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
673 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
674 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
675 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
676 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
677 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
678 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
MTOR 1件: MTOR 💬 |
Sirolimus Sirolimus 💬 |
Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬 |
679 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
680 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
681 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
682 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
683 | Type II diabetes mellitus 💬 14 genes, 39 drugs (DrugBank) and 91 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
684 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA 1件: EDNRA 💬 |
Ambrisentan Ambrisentan 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 💬 |
685 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
686 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
EDNRA 1件: EDNRA 💬 |
Bosentan Bosentan 💬 |
Bosentan | 041 10件: 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 💬 |
687 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
Riociguat Riociguat 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 💬 |
688 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR 1件: PTGIR 💬 |
Iloprost Iloprost 💬 |
Iloprost | 051 4件: 51, 84, 85, 86 💬 💬 |
689 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR 1件: PTGIR 💬 |
Selexipag Selexipag 💬 |
Selexipag | 051 5件: 51, 70, 84, 86, 88 💬 💬 |
690 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
PTGIR 1件: PTGIR 💬 |
Treprostinil Treprostinil 💬 |
Treprostinil | 051 6件: 51, 84, 85, 86, 88, 210 💬 💬 |
691 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
692 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 1件: JAK1 💬 |
Abrocitinib Abrocitinib 💬 |
Abrocitinib | 084 1件: 84 💬 💬 |
693 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 2件: JAK1, JAK3 💬 |
Tofacitinib Tofacitinib 💬 |
Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬 |
694 | Viral life cycle - HIV-1 💬 4 genes, 5 drugs (DrugBank) and 9 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
695 | Viral myocarditis 💬 10 genes, 19 drugs (DrugBank) and 46 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
696 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CCL2 4件: CCL2, IL10, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
697 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
698 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
IL6R 1件: IL6R 💬 |
Sarilumab Sarilumab 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 💬 |
699 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
700 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
701 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
702 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 29 drugs (DrugBank) and 60 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
703 | Virion - Adenovirus 💬 2 genes, 2 drugs (DrugBank) and 26 diseases |
CD80 2件: CD80, CD86 💬 |
Abatacept Abatacept 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬 |
704 | Virion - Human immunodeficiency virus 💬 3 genes, 4 drugs (DrugBank) and 8 diseases |
CCR5 1件: CCR5 💬 |
Maraviroc Maraviroc 💬 |
Maraviroc | 046 2件: 46, 84 💬 💬 |
705 | Virion - Lyssavirus 💬 2 genes, 2 drugs (DrugBank) and 5 diseases |
CHRNA1 1件: CHRNA1 💬 |
Nicotine Nicotine 💬 |
Nicotine | 006 3件: 6 , 13, 84 💬 💬 |
706 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
CCL2 5件: CCL2, IL10, IL1B, IL6, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
707 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
708 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
709 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
710 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
711 | Yersinia infection 💬 22 genes, 39 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |