Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Cholinergic synapse 💬
1件: ACHE 💬 Donepezil 💬 Donepezil 9件:  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬 💬
2 Cholinergic synapse 💬
1件: ACHE 💬 Galantamine 💬 Galantamine 2件:  6 , 127 💬 💬
3 Cholinergic synapse 💬
1件: ACHE 💬 Latrepirdine 💬 Latrepirdine 1件:  8  💬 💬
4 Cholinergic synapse 💬
1件: ACHE 💬 Rivastigmine 💬 Rivastigmine 3件:  5 ,  6 , 13 💬 💬
5 Cholinergic synapse 💬
1件: ACHE 💬 Tacrine 💬 Tacrine 2件: 46, 271 💬 💬
6 Cholinergic synapse 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 1件: 28 💬 💬
7 Cholinergic synapse 💬
5件: CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬 💬
8 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬 💬
9 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬 💬
10 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬 💬
11 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬 💬
12 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 2件: 50, 81 💬 💬
13 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬 💬
14 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬 💬
15 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
16 Cholinergic synapse 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬 💬
17 Cholinergic synapse 💬
9件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Propiverine 💬 Propiverine 1件: 226 💬 💬
18 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine 2件:  2 , 299 💬 💬
19 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Blarcamesine 💬 Blarcamesine 1件: 156 💬 💬
20 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬 💬
21 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬 💬
22 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Scopolamine 💬 Scopolamine 1件:  2  💬 💬
23 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Trihexyphenidyl 💬 Trihexyphenidyl 2件:  5 ,  6  💬 💬
24 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Tropicamide 💬 Tropicamide 1件:  6  💬 💬
25 Cholinergic synapse 💬
2件: CHRM2, CHRM3 💬 Fesoterodine 💬 Fesoterodine 1件:  6  💬 💬
26 Cholinergic synapse 💬
2件: CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine 3件:  6 , 53, 299 💬 💬
27 Cholinergic synapse 💬
1件: CHRM3 💬 Cevimeline 💬 Cevimeline 1件: 53 💬 💬
28 Cholinergic synapse 💬
1件: CHRM3 💬 Darifenacin 💬 Darifenacin 2件:  6 , 13 💬 💬
29 Cholinergic synapse 💬
1件: CHRM3 💬 Solifenacin 💬 Solifenacin 3件:  6 , 13, 53 💬 💬
30 Cholinergic synapse 💬
1件: CHRM3 💬 Tolterodine 💬 Tolterodine 2件: 17, 53 💬 💬
31 Cholinergic synapse 💬
6件: CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 💬 Nicotine 💬 Nicotine 3件:  6 , 13, 84 💬 💬
32 Cholinergic synapse 💬
2件: CHRNA4, CHRNB2 💬 Varenicline 💬 Varenicline 3件:  6 , 18, 53 💬 💬
33 Cholinergic synapse 💬
1件: FYN 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
34 Cholinergic synapse 💬
1件: FYN 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
35 Cholinergic synapse 💬
1件: JAK2 💬 Baricitinib 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
36 Cholinergic synapse 💬
1件: JAK2 💬 Peficitinib 💬 Peficitinib 1件: 46 💬 💬
37 Cholinergic synapse 💬
1件: JAK2 💬 Ruxolitinib 💬 Ruxolitinib 3件: 60, 65, 228 💬 💬
38 Cholinergic synapse 💬
1件: JAK2 💬 Tofacitinib 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
39 Cholinergic synapse 💬
3件: KCNJ12, KCNJ3, KCNQ1 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬 💬
40 Cholinergic synapse 💬
5件: KCNQ1, KCNQ2, KCNQ3, KCNQ4, KCNQ5 💬 Ezogabine 💬 Ezogabine 2件:  2 , 144 💬 💬
41 Cholinergic synapse 💬
1件: MAP2K1 💬 Binimetinib 💬 Binimetinib 1件: 34 💬 💬
42 Cholinergic synapse 💬
1件: MAP2K1 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬 💬
43 Cholinergic synapse 💬
1件: MAP2K1 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬 💬
44 Cholinergic synapse 💬
1件: MAP2K1 💬 Selumetinib 💬 Selumetinib 1件: 34 💬 💬
45 Cholinergic synapse 💬
1件: MAP2K1 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬 💬
46 Cholinergic synapse 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
47 Cholinergic synapse 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
48 Cholinergic synapse 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
49 Cholinergic synapse 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬