Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Human cytomegalovirus infection 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 6件: 19, 60, 65, 284, 285, 326 💬 💬
2 Human cytomegalovirus infection 💬
4件: CCL2, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
3 Human cytomegalovirus infection 💬
1件: CCR5 💬 Cenicriviroc 💬 Cenicriviroc 1件: 94 💬 💬
4 Human cytomegalovirus infection 💬
1件: CCR5 💬 Maraviroc 💬 Maraviroc 2件: 46, 84 💬 💬
5 Human cytomegalovirus infection 💬
2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬 💬
6 Human cytomegalovirus infection 💬
1件: CXCR2 💬 Reparixin 💬 Reparixin 2件: 298, 299 💬 💬
7 Human cytomegalovirus infection 💬
1件: CXCR4 💬 Plerixafor 💬 Plerixafor 5件: 19, 20, 65, 285, 299 💬 💬
8 Human cytomegalovirus infection 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 2件: 51, 86 💬 💬
9 Human cytomegalovirus infection 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 1件: 94 💬 💬
10 Human cytomegalovirus infection 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬 💬
11 Human cytomegalovirus infection 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬 💬
12 Human cytomegalovirus infection 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬 💬
13 Human cytomegalovirus infection 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬 💬
14 Human cytomegalovirus infection 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬 💬
15 Human cytomegalovirus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬 💬
16 Human cytomegalovirus infection 💬
13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬 💬
17 Human cytomegalovirus infection 💬
1件: IL1B 💬 Canakinumab 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬
18 Human cytomegalovirus infection 💬
1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬 💬
19 Human cytomegalovirus infection 💬
1件: IL1B 💬 Rilonacept 💬 Rilonacept 4件: 51, 106, 107, 266 💬 💬
20 Human cytomegalovirus infection 💬
1件: IL1R1 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
21 Human cytomegalovirus infection 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬 💬
22 Human cytomegalovirus infection 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬 💬
23 Human cytomegalovirus infection 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬 💬
24 Human cytomegalovirus infection 💬
2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
25 Human cytomegalovirus infection 💬
1件: IL6R 💬 Sarilumab 💬 Sarilumab 5件: 41, 46, 84, 107, 271 💬 💬
26 Human cytomegalovirus infection 💬
1件: IL6R 💬 Satralizumab 💬 Satralizumab 3件: 11, 13, 86 💬 💬
27 Human cytomegalovirus infection 💬
1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 21件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 💬
28 Human cytomegalovirus infection 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 1件: 84 💬 💬
29 Human cytomegalovirus infection 💬
1件: JAK1 💬 Baricitinib 💬 Baricitinib 13件:  2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬
30 Human cytomegalovirus infection 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 6件: 46, 53, 96, 97, 222, 271 💬 💬
31 Human cytomegalovirus infection 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬 💬
32 Human cytomegalovirus infection 💬
1件: JAK1 💬 Peficitinib 💬 Peficitinib 1件: 46 💬 💬
33 Human cytomegalovirus infection 💬
1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 3件: 60, 65, 228 💬 💬
34 Human cytomegalovirus infection 💬
1件: JAK1 💬 Tofacitinib 💬 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬 💬
35 Human cytomegalovirus infection 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬 💬
36 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬 💬
37 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬 💬
38 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 1件: 34 💬 💬
39 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬 💬
40 Human cytomegalovirus infection 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 4件:  2 , 34, 279, 280 💬 💬
41 Human cytomegalovirus infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬 💬
42 Human cytomegalovirus infection 💬
4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬 💬
43 Human cytomegalovirus infection 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬 💬
44 Human cytomegalovirus infection 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 40件:  2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬 💬
45 Human cytomegalovirus infection 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 1件: 13 💬 💬
46 Human cytomegalovirus infection 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
47 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬
48 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬 💬
49 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬 💬
50 Human cytomegalovirus infection 💬
1件: PDGFRA 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬 💬
51 Human cytomegalovirus infection 💬
1件: PIK3CA 💬 Alpelisib 💬 Alpelisib 1件: 138 💬 💬
52 Human cytomegalovirus infection 💬
3件: PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬 💬
53 Human cytomegalovirus infection 💬
1件: PIK3CD 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬 💬
54 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Cyclosporine 💬 Cyclosporine 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 💬
55 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬 💬
56 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
57 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus 34件:  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬 💬
58 Human cytomegalovirus infection 💬
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬 💬
59 Human cytomegalovirus infection 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬 💬
60 Human cytomegalovirus infection 💬
1件: PTGER1 💬 Alprostadil 💬 Alprostadil 2件: 51, 70 💬 💬
61 Human cytomegalovirus infection 💬
1件: PTGER1 💬 Limaprost 💬 Limaprost 1件: 70 💬 💬
62 Human cytomegalovirus infection 💬
3件: PTGER2, PTGER3, PTGER4 💬 Misoprostol 💬 Misoprostol 3件: 46, 70, 271 💬 💬
63 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬 💬
64 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬
65 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬
66 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Celecoxib 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬
67 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬 💬
68 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬 💬
69 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Etodolac 💬 Etodolac 1件: 46 💬 💬
70 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 2件: 46, 271 💬 💬
71 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬 💬
72 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬
73 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬 💬
74 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 1件: 46 💬 💬
75 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬 💬
76 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬 💬
77 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬 💬
78 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Meloxicam 💬 Meloxicam 4件: 46, 49, 271, 296 💬 💬
79 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬 💬
80 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬 💬
81 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬 💬
82 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬 💬
83 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬 💬
84 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬 💬
85 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬 💬
86 Human cytomegalovirus infection 💬
1件: PTGS2 💬 Valdecoxib 💬 Valdecoxib 1件: 46 💬 💬
87 Human cytomegalovirus infection 💬
1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
88 Human cytomegalovirus infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
89 Human cytomegalovirus infection 💬
2件: ROCK1, ROCK2 💬 Fasudil 💬 Fasudil 4件:  2 ,  5 ,  7 , 51 💬 💬
90 Human cytomegalovirus infection 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 2件: 51, 85 💬 💬
91 Human cytomegalovirus infection 💬
1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬 💬
92 Human cytomegalovirus infection 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
93 Human cytomegalovirus infection 💬
1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬 💬
94 Human cytomegalovirus infection 💬
1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬 💬
95 Human cytomegalovirus infection 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬
96 Human cytomegalovirus infection 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬
97 Human cytomegalovirus infection 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬
98 Human cytomegalovirus infection 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬
99 Human cytomegalovirus infection 💬
1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬
100 Human cytomegalovirus infection 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬
101 Human cytomegalovirus infection 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬 💬
102 Human cytomegalovirus infection 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬 💬
103 Human cytomegalovirus infection 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬
104 Human cytomegalovirus infection 💬
1件: VEGFA 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬 💬
105 Human cytomegalovirus infection 💬
1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 6件: 13, 34, 85, 87, 227, 280 💬 💬
106 Human cytomegalovirus infection 💬
1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬 💬