Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
BCL2 1件: BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 1件: 28 💬
|
2 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Rontalizumab Rontalizumab 💬
| Rontalizumab | 049 1件: 49 💬
|
3 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNA1 13件: IFNA1, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA2, IFNA21, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8 💬
|
Sifalimumab Sifalimumab 💬
| Sifalimumab | 049 1件: 49 💬
|
4 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Anifrolumab Anifrolumab 💬
| Anifrolumab | 046 3件: 46, 49, 53 💬
|
5 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 013 6件: 13, 25, 26, 28, 56, 96 💬
|
6 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 1件: 56 💬
|
7 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 2件: 25, 34 💬
|
8 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon beta-1a Interferon beta-1a 💬
| Interferon beta-1a | 013 4件: 13, 26, 96, 97 💬
|
9 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon beta-1b Interferon beta-1b 💬
| Interferon beta-1b | 013 1件: 13 💬
|
10 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Peginterferon beta-1a Peginterferon beta-1a 💬
| Peginterferon beta-1a | 013 1件: 13 💬
|
11 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNG 1件: IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 3件: 49, 65, 107 💬
|
12 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNG 1件: IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 1件: 46 💬
|
13 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬
|
14 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
15 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
16 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
17 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
18 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
19 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 1件: JAK1 💬
|
Abrocitinib Abrocitinib 💬
| Abrocitinib | 084 1件: 84 💬
|
20 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 1件: JAK1 💬
|
Filgotinib Filgotinib 💬
| Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬
|
21 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 1件: JAK1 💬
|
Itacitinib Itacitinib 💬
| Itacitinib | 046 4件: 46, 51, 97, 228 💬
|
22 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
23 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
24 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Ruxolitinib Ruxolitinib 💬
| Ruxolitinib | 060 3件: 60, 65, 228 💬
|
25 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 1件: 46 💬
|
26 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
27 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
PARP1 1件: PARP1 💬
|
Olaparib Olaparib 💬
| Olaparib | 086 2件: 86, 285 💬
|
28 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
SMPD1 1件: SMPD1 💬
|
Olipudase alfa Olipudase alfa 💬
| Olipudase alfa | 019 1件: 19 💬
|
29 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
|
30 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
|
31 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
|
32 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
|
33 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
|
34 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
|
35 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 1件: 46 💬
|
36 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 1件: 46 💬
|
37 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬
|
38 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
|
39 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
TYK2 1件: TYK2 💬
|
Deucravacitinib Deucravacitinib 💬
| Deucravacitinib | 049 3件: 49, 96, 97 💬
|