Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Oxygen 💬 [1] Oxygen[3] Medical air; Nitrogen; Oxygen; --[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330 💬
2 Glucose 💬 [1] D-glucose[2] D-glucose; Glucose; --[3] 49, 86, 88 💬
3 Nitric oxide 💬 [1] Nitric Oxide[3] INOmax; Nitric Oxide; Nitrosyl; --[7] 85, 86, 88, 210, 251, 294, 299 💬
4 Bosentan 💬 [1] Bosentan[2] Bosentan; Tracleer; [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
5 Fludeoxyglucose F 18 💬 [1] Fludeoxyglucose[1] Fludeoxyglucose; --[3] 84, 85, 88 💬
6 Treprostinil 💬 [1] Treprostinil[4] Remodulin; Treprostinil; Treprostinilo; Tyvaso; [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210 💬
7 Ambrisentan 💬 [1] Ambrisentan[3] AMBRISENTAN; Letairis; VOLIBRIS; [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 51, 84, 85, 86, 88, 210, 211 💬
8 Atorvastatin 💬 [1] Atorvastatin[3] Atorvastatin; Atorvastatin calcium; Lipitor; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
9 Bosentan 💬 [1] Bosentan[2] Bosentan; Tracleer; [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
10 Gadobenic acid 💬 [1] Gadobenic acid[2] Gadobenate; MultiHance; --[3] 13, 86, 88 💬
11 Imatinib 💬 [1] Imatinib[4] Gleevec; GLIVEC; Imatinib; Imatinib Mesylate; [3] ABL1,
KIT,
PDGFRA 💬		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
12 Potassium 💬 [1] Potassium[1] Potassium; --[13] 36, 46, 66, 67, 88, 93, 94, 98, 115, 167, 179, 215, 235 💬
13 Warfarin 💬 [1] Warfarin[2] Warfarin; Warfarin Sodium; [2] NQO1,
VKORC1 💬		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
14 Dapagliflozin 💬 [1] Dapagliflozin[2] Dapagliflozin; Forxiga; [1] SLC5A2 💬[1] 💬[7] 19, 49, 66, 67, 86, 88, 222 💬
15 Riociguat 💬 [1] Riociguat[2] Adempas; RIOCIGUAT; [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299 💬
16 Edoxaban 💬 [1] Edoxaban[1] Edoxaban; [1] F10 💬[1] Complement and coagulation cascades 💬[2] 46, 88 💬
17 Selexipag 💬 [1] Selexipag[2] SELEXIPAG; Uptravi; [1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[5] 51, 70, 84, 86, 88 💬
18 Macitentan 💬 [1] Macitentan[2] MACITENTAN; Opsumit; [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 51, 85, 86, 88, 210 💬