Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[20] EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 ...

[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
28	Systemic amyloidosis
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
51	Scleroderma
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
87	Pulmonary veno-occlusive disease
88	Chronic thromboembolic pulmonary hypertension
89	Lymphangioleiomyomatosis
162	Pemphigoid

2

[20] EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 ...

[2] 28, 34 💬

3

[20] EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 ...

[5] 6, 8, 34, 51, 86 💬

4

[20] EGFR tyrosine kinase inhibitor resistance, MAPK signaling pathway, Ras signaling pathway, Rap1 ...

Nintedanib 💬

[5] 51, 85, 89, 227, 228 💬

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