Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen
(Synonym: Trendar Pms Caplet)		4件: Acetaminophen; PARACETAMOL; Tylenol; Ultracet1件: D00217 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬15件: 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Acetic acid
(Synonym: Treagan Otic)		2件: Acetic acid; Ethanoate1件: D00010 --2件: 97, 251
3 Adenosine
(Synonym: MISSHA Time Revolution The First Treatment Essence Mask)		2件: Adenosine; Ginseng1件: D00045 4件: ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		12件: Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 13, 58, 65
4 Alitretinoin
(Synonym: 9-cis-Tretinoin)		2件: ALITRETINOIN; Toctino1件: D02815 5件: RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		19件: Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬1件: 49
5 Allantoin
(Synonym: Dr Deep Acpa Tea TreeLotion)		1件: ALLANTOIN1件: D00121 --1件: 36
6 Antihemophilic factor human
(Synonym: Profilate Heat Treated-wet Method Inj)		6件: Alphanate; Factor VIII; HUMAN COAGULATION FACTOR VIII; Humate-P; Voncento; WILATE---1件: 288
7 Bendamustine
(Synonym: Treanda)		2件: Bendamustine; BENDAMUSTINE HYDROCHLORIDE1件: D07501 (Name: Treanda (TN))--2件: 28, 61
8 Biotin
(Synonym: Bonogen Activator hair loss treatment)		4件: Biotin; Biotina; D-BIOTIN; Vitamin B71件: D00029 --5件: 2, 8, 10, 13, 20
9 Butylene glycol
(Synonym: Buddate Reges Intensive Treatment)		0件: 1件: D10695 --2件: 28, 56
10 Caffeine
(Synonym: Trezix)		1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 21, 46, 78, 96, 97, 265
11 Calcium
(Synonym: Restoration Treatment)		2件: Calcio; Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
12 Calcium carbonate
(Synonym: D B Tre)		3件: Calcio carbonato; Calcium; Calcium Carbonate2件: D00932 ,
D10802 		--9件: 13, 19, 46, 53, 75, 96, 235, 274, 299
13 Catridecacog
(Synonym: Tretten)		1件: Catridecacog1件: D10532 --2件: 97, 288
14 Chlorpheniramine
(Synonym: Anakit Insect Sting Treatment Kit)		1件: Clorfenamina1件: D07398 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 14
15 Clindamycin
(Synonym: Clindamycin Phosphate and Tretinion)		2件: Clindamycin; Dalacin C phosphate1件: D00277 --2件: 46, 299
16 Clotrimazole
(Synonym: Terrasil Anti-Fungal Treatment MAX)		1件: Clotrimazole1件: D00282 --1件: 97
17 Dihydrocodeine
(Synonym: Trezix)		0件: 1件: D07831 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 310
18 Epinephrine
(Synonym: Anakit Insect Sting Treatment Kit)		3件: Epinephrine; Lidocaine; Xylocaine1件: D00095 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬3件: 46, 70, 96
19 Esomeprazole
(Synonym: Berkley and Jensen Heartburn Treatment)		3件: Esomeprazole; Nexium; Omeprazole1件: D07917 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
20 Ethanol
(Synonym: Botanic Tree Hand Sanitizer)		3件: Alcohol; Ethanol; PREDNISONE1件: D06542 --5件: 58, 97, 279, 280, 298
21 Ginkgo biloba
(Synonym: Maidenhair tree leaf)		3件: Ginkgo; Ginkgo biloba; Tanakan---5件: 6, 13, 18, 47, 90
22 Glycerin
(Synonym: Blister Balm Protective Lip Treatment)		2件: Bee venom; Glycerol1件: D00028 --5件: 6, 13, 79, 316, 317
23 Glycine
(Synonym: CAREDO Treating Gingivitis Toothpastes 100g)		1件: GLYCINE1件: D00011 --5件: 35, 60, 86, 226, 299
24 Guselkumab
(Synonym: Tremfya)		2件: GUSELKUMAB; TREMFYA1件: D10438 (Name: Tremfya (TN))1件: IL23A 💬9件: C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬5件: 37, 41, 51, 96, 97
25 Histidine
(Synonym: CAREDO Treating Periodontitis Toothpastes 100g)		2件: Histidine; L-Histidine1件: D00032 --3件: 13, 169, 170
26 Horse chestnut 1件: Horse chestnut1件: D12028 (Name: Conker tree)--1件: 210
27 Hydrocortisone
(Synonym: Post-Treatment Repair Cream)		6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
28 Hydrocortisone acetate
(Synonym: Irritated Skin Treatment)		2件: Hydrocortisone; HYDROCORTISONE ACETATE1件: D00165 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
29 Lansoprazole
(Synonym: Rugby Heartburn Treatment)		1件: Lansoprazole1件: D00355 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299
30 Lidocaine
(Synonym: Family Medic First Aid Treatment - Liq)		4件: Aloe; Lidocaine; Lignocaine; Xylocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬13件: 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
31 Methotrexate
(Synonym: Trexall)		6件: Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate1件: D00142 2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬38件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
32 Minoxidil
(Synonym: GROFULLY Womens Hair Regrowth Treatment)		1件: MINOXIDIL1件: D00418 2件: ABCC8,
KCNJ11 💬		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬1件: 179
33 Naproxen
(Synonym: Treximet)		5件: Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid1件: D00118 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬4件: 13, 46, 107, 271
34 Nicotinamide
(Synonym: Elastine Hair Gain Treatment)		3件: Multivitamin; Niacinamide; NICOTINAMIDE1件: D00036 --10件: 2, 5, 6, 18, 49, 67, 97, 107, 162, 191
35 Olive oil
(Synonym: Intensive Treatment Bodyoil for Mommy To Be All Skin)		1件: Olive oil1件: D03311 --5件: 13, 35, 49, 53, 162
36 Pentoxifylline
(Synonym: Trental Srt 400mg)		1件: Pentoxifylline1件: D00501 (Name: Trental (TN))--12件: 26, 56, 84, 86, 93, 96, 97, 113, 220, 222, 296, 298
37 Petrolatum
(Synonym: Maximum Strength Cold Sore Treatment)		1件: Petrolatum1件: D05331 --1件: 158
38 Phenylephrine
(Synonym: Trexbrom)		1件: Phenylephrine1件: D08365 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 22
39 Salicylic acid
(Synonym: Seaseal Bamboo Salt Mineral Hair Treatment)		2件: 2-Hydroxybenzoic acid; Salicylic acid1件: D00097 --1件: 97
40 Sodium fluoride
(Synonym: Fluoride Treatment)		1件: Sodium fluoride1件: D00943 --1件: 51
41 Threonine
(Synonym: Treonina)		1件: Threonine1件: D00041 --2件: 86, 97
42 Thymol
(Synonym: Acne Vanish Synergy for treatment of Acnes)		1件: Thymol1件: D01039 --1件: 13
43 Tregalizumab 1件: Tregalizumab---1件: 46
44 Trehalose 2件: Cabaletta; Trehalose---4件: 2, 6, 18, 113
45 Tremelimumab 1件: Ticilimumab1件: D06657 (Name: Tremelimumab)1件: CTLA4 💬4件: Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬1件: 96
46 Treosulfan 2件: OVASTAT; Treosulfan1件: D07253 (Name: Treosulfan)--6件: 13, 19, 62, 65, 283, 286
47 Treprostinil 4件: Remodulin; Treprostinil; Treprostinilo; Tyvaso1件: D06213 (Name: Treprostinil)1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬6件: 51, 84, 85, 86, 88, 210
48 Tretinoin 5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID1件: D00094 (Name: Tretinoin)3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231
49 Triamcinolone
(Synonym: Treziopak)		4件: Kenalog; Naltrexone; Triamcinolone; TRIAMCINOLONE ACETONIDE1件: D00385 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298
50 Triptorelin
(Synonym: Trelstar)		2件: GnRH; Triptorelin1件: D06247 1件: GNRHR 💬2件: GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬2件: 49, 76
51 Zinc oxide
(Synonym: Exuviance CoverBlend Concealing Treatment Makeup SPF 30 Desert Sand)		1件: Zinc oxide1件: D01170 --1件: 156