Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
2 Alcoholism 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
3 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
4 Alzheimer disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
5 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
6 Amphetamine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
7 Amyotrophic lateral sclerosis 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
8 Amyotrophic lateral sclerosis 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
9 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
10 Calcium signaling pathway 💬
 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
11 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
12 cAMP signaling pathway 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
13 cGMP-PKG signaling pathway 💬
 3件: ADRA2A, ADRA2B, ADRA2C 💬 D00514 💬 Dexmedetomidine 14件:  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
14 Circadian entrainment 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
15 Circadian entrainment 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
16 Cocaine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
17 Cocaine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
18 Cortisol synthesis and secretion 💬
 1件: KCNA4 💬 D04127 💬 Dalfampridine 5件:  3 ,  4 ,  6 , 13, 14 💬
19 Cushing syndrome 💬
 1件: KCNA4 💬 D04127 💬 Dalfampridine 5件:  3 ,  4 ,  6 , 13, 14 💬
20 Dopaminergic synapse 💬
 2件: GRIN2A, GRIN2B 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
21 Dopaminergic synapse 💬
 2件: GRIN2A, GRIN2B 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
22 ECM-receptor interaction 💬
 1件: SV2A 💬 D00709 💬 Levetiracetam 5件:  2 ,  4 ,  6 , 13, 307 💬
23 Glutamatergic synapse 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
24 Glutamatergic synapse 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
25 Huntington disease 💬
 2件: GRIN1, GRIN2B 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
26 Huntington disease 💬
 2件: GRIN1, GRIN2B 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
27 Long-term potentiation 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
28 Long-term potentiation 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
29 Neuroactive ligand-receptor interaction 💬
 3件: ADRA2A, ADRA2B, ADRA2C 💬 D00514 💬 Dexmedetomidine 14件:  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
30 Neuroactive ligand-receptor interaction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
31 Neuroactive ligand-receptor interaction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
32 Nicotine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
33 Nicotine addiction 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
34 Pathways of neurodegeneration - multiple diseases 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
35 Pathways of neurodegeneration - multiple diseases 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
36 Prion disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
37 Prion disease 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
38 Rap1 signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
39 Rap1 signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
40 Ras signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
41 Ras signaling pathway 💬
 3件: GRIN1, GRIN2A, GRIN2B 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
42 Serotonergic synapse 💬
 1件: KCND2 💬 D04127 💬 Dalfampridine 5件:  3 ,  4 ,  6 , 13, 14 💬
43 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
44 Spinocerebellar ataxia 💬
 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
45 Spinocerebellar ataxia 💬
 2件: KCNC3, KCND3 💬 D04127 💬 Dalfampridine 5件:  3 ,  4 ,  6 , 13, 14 💬
46 Systemic lupus erythematosus 💬
 2件: GRIN2A, GRIN2B 💬 D07283 💬 Esketamine 3件:  2 ,  4 , 70 💬
47 Systemic lupus erythematosus 💬
 2件: GRIN2A, GRIN2B 💬 D08098 💬 Ketamine 8件:  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬

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