Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Complement and coagulation cascades 💬
3件: C1R, C1S, KLKB1 💬 D10845 💬 Conestat alfa 1件: 61 💬
2 Complement and coagulation cascades 💬
1件: C1S 💬 D11530 💬 Sutimlimab 1件: 61 💬
3 Complement and coagulation cascades 💬
1件: C3 💬 D11613 💬 Pegcetacoplan 4件:  2 , 61, 62, 222 💬
4 Complement and coagulation cascades 💬
1件: C5 💬 D11696 💬 Crovalimab 2件: 62, 109 💬
5 Complement and coagulation cascades 💬
1件: C5 💬 D03940 💬 Eculizumab 7件: 11, 13, 14, 61, 62, 109, 222 💬
6 Complement and coagulation cascades 💬
1件: C5 💬 D11473 💬 Nomacopan 3件: 62, 109, 162 💬
7 Complement and coagulation cascades 💬
1件: C5 💬 D11477 💬 Pozelimab 2件: 11, 62 💬
8 Complement and coagulation cascades 💬
1件: C5 💬 D11054 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬
9 Complement and coagulation cascades 💬
1件: C5 💬 D11838 💬 Vilobelimab 3件: 43, 44, 269 💬
10 Complement and coagulation cascades 💬
1件: C5 💬 D12357 💬 Zilucoplan 3件:  2 , 11, 62 💬
11 Complement and coagulation cascades 💬
1件: C5AR1 💬 D11093 💬 Avacopan 3件: 43, 44, 222 💬
12 Complement and coagulation cascades 💬
1件: CFB 💬 D12251 💬 Iptacopan 5件: 61, 62, 66, 109, 222 💬
13 Complement and coagulation cascades 💬
1件: CFD 💬 D11641 💬 Danicopan 1件: 62 💬
14 Complement and coagulation cascades 💬
1件: F10 💬 D03213 💬 Apixaban 1件: 222 💬
15 Complement and coagulation cascades 💬
1件: F10 💬 D09710 💬 Edoxaban 2件: 46, 88 💬
16 Complement and coagulation cascades 💬
1件: F10 💬 D07086 💬 Rivaroxaban 4件: 46, 49, 91, 210 💬
17 Complement and coagulation cascades 💬
2件: F10, F9 💬 D10821 💬 Emicizumab 1件: 288 💬
18 Complement and coagulation cascades 💬
1件: F2 💬 D09707 💬 Dabigatran 5件: 51, 75, 85, 91, 124 💬
19 Complement and coagulation cascades 💬
1件: F2 💬 D07144 💬 Dabigatran etexilate 2件: 51, 75 💬
20 Complement and coagulation cascades 💬
1件: F2 💬 D06410 💬 Thrombomodulin Alfa 1件: 85 💬
21 Complement and coagulation cascades 💬
1件: F8 💬 D00291 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
22 Complement and coagulation cascades 💬
1件: MASP2 💬 D11531 💬 Narsoplimab 4件: 64, 66, 109, 222 💬
23 Complement and coagulation cascades 💬
1件: PLG 💬 D00160 💬 Aminocaproic acid 1件: 70 💬
24 Complement and coagulation cascades 💬
1件: PLG 💬 D01136 💬 Tranexamic acid 7件: 46, 70, 215, 227, 274, 288, 299 💬
25 Complement and coagulation cascades 💬
1件: SERPINC1 💬 D07510 💬 Enoxaparin 1件: 46 💬
26 Complement and coagulation cascades 💬
1件: SERPINC1 💬 D07510 💬 Heparin 11件: 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬
27 Complement and coagulation cascades 💬
1件: SERPINC1 💬 D07510 💬 Parnaparin 1件: 97 💬
28 Complement and coagulation cascades 💬
2件: SERPINC1, SERPIND1 💬 D08547 💬 Sulodexide 2件: 51, 271 💬
29 Complement and coagulation cascades 💬
1件: VWF 💬 D11160 💬 Caplacizumab 1件: 64 💬