Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetylcysteine [3] Acetylcysteine; Mucomyst; N-Acetylcysteine[1] D00221 --[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
2 Bupropion [2] Bupropion; Bupropion Hydrochloride[1] D07591 [2] SLC6A2,
SLC6A3 💬		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171
3 Caffeine [1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
4 Cariprazine [1] Reagila[1] D09997 [3] DRD2,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 21
5 Cysteamine [8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; CYSTEAMINE; Mercaptamina; Mercaptamine; PROCYSBI[1] D03634 --[4] 8, 19, 21, 299
6 Dexmedetomidine [4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE[1] D00514 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
7 Dextromethorphan [4] Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta[1] D03742 [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
8 Elamipretide [1] ELAMIPRETIDE[1] D10925 --[2] 21, 324
9 Flurbiprofen [1] Flurbiprofen[1] D00330 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46
10 Haemagglutinin-strain B [2] Fluzone; Influvac---[4] 21, 46, 49, 50
11 Influenza A virus A/Brisbane/59/2007 (H1N1) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
12 Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
13 Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
14 Influenza A virus A/Texas/50/2012 X-223A (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
15 Influenza A virus A/Uruguay/716/2007(H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
16 Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
17 Influenza A virus A/Victoria/361/2011 IVR-165 (H3N2) antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
18 Influenza B virus B/Brisbane/60/2008 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
19 Influenza B virus B/Massachusetts/2/2012 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
20 Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
21 Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
22 Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated) [1] Fluzone---[2] 21, 49
23 Midazolam [2] Midazolam; Midazolam injection[1] D00550 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299
24 Omeprazole [4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[1] D00455 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
25 Phenylbutyric acid [4] 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate---[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338
26 Propofol [2] PROPOFOL; Propofol Injection[1] D00549 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[9] 6, 21, 22, 34, 46, 70, 75, 98, 296
27 Repaglinide [1] Repaglinide[1] D00594 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299
28 Sevoflurane [1] Sevoflurane[1] D00547 --[7] 6, 21, 22, 34, 98, 225, 296
29 Sonlicromanol [1] Sonlicromanol---[1] 21
30 Tocotrienol [1] Tocotrienol---[3] 21, 156, 299
31 Uridine triacetate [1] Tri-O-acetyluridine[1] D09985 --[1] 21
32 Vatiquinone [1] VATIQUINONE[1] D10407 --[2] 18, 21