Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Nalocet)		[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
2 Buprenorphine
(PMS-buprenorphine-naloxone)		[1] Buprenorphine[1] Buprenorphine 💬 [2] OPRK1,
OPRM1 💬 		[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[2] 46, 70 💬
3 Bupropion
(Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release)		[2] Bupropion; Bupropion Hydrochloride[1] Bupropion 💬 [2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171 💬
4 Cromoglicic acid
(Nalcrom)		[4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium[1] Cromoglicic acid 💬 --[3] 2, 85, 98 💬
5 Nalbuphine
(Nalbuphinum)		[2] Nalbuphine; NALBUPHINE HYDROCHLORIDE[1] Nalbuphine (Nalbuphine) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85 💬
6 Nalmefene
(Nalmefeno)		[1] Nalmefene[1] Nalmefene (Nalmefene) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
7 Naloxone
(Pentazocine and naloxone)		[2] Naloxone; NALOXONE HYDROCHLORIDE[1] Naloxone (Naloxone, DBL Naloxone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
8 Naltrexone
(Naltrexona)		[2] Naltrexone; Naltrexone hydrochloride[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[13] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
9 Oxycodone
(Nalocet)		[2] Oxycodone; OXYCODONE HYDROCHLORIDE[1] Oxycodone 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
10 Triamcinolone
(Naltrexone)		[4] Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide[1] Triamcinolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[11] 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬