Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Adenosine 💬[1] Adenosine (Miesoo Perfect Pure Seed Cycling Ampoule)[2] Adenosine; Ginseng[4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬 		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65 💬
2 Ambroxol 💬[1] Ambroxol (trans-4-cyclohexanol)[1] Ambroxol--[2] 6, 19 💬
3 Amitriptyline 💬[1] Amitriptyline (5-cycloheptene)[3] Amitriptylin; AMITRIPTYLINE; Amitriptyline hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 78, 97, 226, 299 💬
4 Betadex 💬[1] Betadex (Cyclodextrin B)[1] Beta-cyclodextrin--[1] 19 💬
5 Bromocriptine 💬[1] Bromocriptine (Cycloset)[1] BROMOCRIPTINE[2] DRD2,
PRL 💬 		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 74 💬
6 Bucladesine 💬[1] Bucladesine (dibutyryl cyclic AMP)[1] Bucladesine[16] PDE10A,
PDE11A,
PDE1A,
PDE1B,
PDE1C,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE7A,
PDE7B,
PDE8A,
PDE8B 💬 		[18] Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 246 💬
7 Capsaicin 💬[1] Capsaicin (CyclobenzaprinePax)[2] Capsaicin; Qutenza[1] TRPV1 💬 [2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226 💬
8 Ciprofloxacin 💬[1] Ciprofloxacin (1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid)[2] Ciprofloxacin; Ciprofloxacin hydrochloride--[5] 2, 60, 96, 97, 299 💬
9 Cyclophosphamide 💬
(Cyclophosphamide (INN), Cyclophosphamide (TN))		[1] Cyclophosphamide (Bisphosphoramide cyclic propanolamide ester)[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
10 Cyclophosphamide 💬
(Cyclophosphamide (USP), Cyclophosphamide hydrate (JP18))		[1] Cyclophosphamide (Bisphosphoramide cyclic propanolamide ester)[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
11 Cyclosporine 💬
(Cyclosporine (USP), CYCLOSPORINE, MODFIED)		[1] Cyclosporine (Cyclosporine Capsules)[10] Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; RESTASIS[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
12 Danazol 💬[1] Danazol (Cyclomen)[1] Danazol[3] AR,
ESR1,
PGR 💬 		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285 💬
13 Desogestrel 💬[1] Desogestrel (Cyclessa)[2] Desogestrel; Désogestrel[2] ESR1,
PGR 💬 		[11] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 230 💬
14 Esketamine 💬[1] Esketamine (cyclohexanone)[3] Esketamine; KETAMINE; S-ketamine[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[3] 2, 4, 70 💬
15 Estrogens, conjugated 💬[1] Conjugated estrogens (Premplus Cycle)[1] Conjugated equine estrogens--[1] 49 💬
16 Ethinyl estradiol 💬[1] Ethinylestradiol (Ortho Tri Cyclen)[3] Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 777[1] ESR1 💬 [9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 13, 46, 49, 299 💬
17 Gabapentin 💬[1] Gabapentin (Cyclo/Gaba 10/300 Pack)[4] Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
18 Hydrocortisone cypionate 💬[1] Hydrocortisone cypionate (Cortisol 21-cyclopentanepropionate)[1] Cortef[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[3] 6, 81, 83 💬
19 Ketamine 💬[1] Ketamine (2-cyclohexanone)[2] KETAMINE; NMDA[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[6] 6, 13, 70, 113, 156, 215 💬
20 Lidocaine 💬[1] Lidocaine (Cyclopak)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
21 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine (Cyclopak)[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
22 Magnesium oxide 💬[1] Magnesium oxide (Cyclo/Mag 10mg/200mg)[1] Magnesium oxide--[3] 6, 166, 291 💬
23 Medroxyprogesterone acetate 💬[1] Medroxyprogesterone acetate (Premplus Cycle)[1] Medroxyprogesterone[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 49 💬
24 Montelukast 💬[1] Montelukast (cyclopropaneacetic acid)[3] Montelukast; MONTELUKAST SODIUM; Singulair[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228 💬
25 Naltrexone 💬[1] Naltrexone (N-Cyclopropylmethyl-14-hydroxydihydromorphinone)[2] Naltrexone; Naltrexone Hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
26 Niacinamide 💬[1] Nicotinamide (Miesoo Perfect Pure Seed Cycling Ampoule)[3] Multivitamin; Niacinamide; NICOTINAMIDE--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
27 Norethindrone 💬[1] Norethisterone (Cyclafem 7/7/7)[3] Norethindrone; Ortho-novum; Ortho-Novum 777[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[4] 13, 46, 49, 299 💬
28 Norgestimate 💬[1] Norgestimate (ORTHO TRI CYCLEN Lo)[1] Norgestimate[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 299 💬
29 Oseltamivir 💬[1] Oseltamivir (Ethyl -1-cyclohexene-1-carboxylate)[1] Oseltamivir--[2] 97, 299 💬
30 Oxybutynin 💬[1] Oxybutynin (4-Diethylamino-2-butinyl alpha-cyclohexylmandelat)[1] Oxybutynin[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
31 Pasireotide 💬[1] Pasireotide (cyclo)[3] Pasireotida; PASIREOTIDE; SIGNIFOR[4] SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		[4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[3] 67, 74, 75 💬
32 Phenylephrine 💬[1] Phenylephrine (Cyclomydril)[1] Phenylephrine[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22 💬
33 Tranexamic acid 💬[1] Tranexamic acid (trans-4-cyclohexanecarboxylic acid)[1] Tranexamic acid[1] PLG 💬 [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬[7] 46, 70, 215, 227, 274, 288, 299 💬