206. 脆弱Ｘ症候群 Fragile X syndrome Clinical trials / Disease details
臨床試験数 : 108 / 薬物数 : 91 - (DrugBank : 36) / 標的遺伝子数 : 52 - 標的パスウェイ数 : 77
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02680379 (ClinicalTrials.gov) | March 2016 | 25/1/2016 | Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X Syndrome | A Pilot Study Exploring the Safety and Synergistic Effect of a Minocycline/Lovastatin Combined Treatment on the Behavior of Individuals With Fragile X Syndrome; Validation of New Biochemical and Neurophysiological Markers (LovaMiX) | Fragile X Syndrome | Drug: Minocycline, then Minocycline/Lovastatin;Drug: Lovastatin, then Minocycline/Lovastatin | Université de Sherbrooke | FRAXA Research Foundation | Completed | 8 Years | 45 Years | All | 22 | Phase 2 | Canada |
| 2 | NCT02998151 (ClinicalTrials.gov) | January 2016 | 1/12/2016 | Neurophysiological and Acute Pharmacological Studies in FXS Patients | Neurophysiological and Acute Pharmacological Studies in FXS Patients | Fragile X Syndrome | Drug: Acamprosate;Drug: Lovastatin;Drug: Minocycline;Drug: Placebo;Drug: Baclofen | Children's Hospital Medical Center, Cincinnati | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Completed | 15 Years | 55 Years | All | 29 | Early Phase 1 | United States |
| 3 | NCT01053156 (ClinicalTrials.gov) | January 2010 | 19/1/2010 | Trial of Minocycline to Treat Children With Fragile X Syndrome | Randomized Double-Blind Controlled Cross Over Trial of Minocycline in Children With Fragile X Syndrome | Fragile X Syndrome | Drug: minocycline hydrochloride;Drug: Placebo | University of California, Davis | The National Fragile X Foundation | Completed | 42 Months | 16 Years | All | 66 | N/A | United States |
| 4 | NCT00858689 (ClinicalTrials.gov) | October 2007 | 9/3/2009 | Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome | Add-on Pilot Trial of Minocycline in Fragile X Syndrome | Fragile X Syndrome | Drug: Minocycline | FRAXA Research Foundation | Fragile X Research Foundation of Canada | Completed | 13 Years | 35 Years | All | 20 | N/A | Canada |