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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acetate1件: Acetate---41件: 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299
2ADVATE1件: Antihemophilic factor, human recombinant---1件: 288
3ADVATE (rAHF - PFM)1件: Antihemophilic factor, human recombinant---1件: 288
4ADVATE (rAHF-PFM)1件: Antihemophilic factor, human recombinant---1件: 288
5ADVATE 1000 IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant---1件: 288
6ADVATE 1000IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant---1件: 288
7ADVATE 500 IU powder and solvent for solution for injection1件: Antihemophilic factor, human recombinant---1件: 288
8Alphanate1件: Von Willebrand factor human---1件: 288
9Alphanate 1000 I.U.1件: Von Willebrand factor human---1件: 288
10Alphanate 1500 I.U.1件: Von Willebrand factor human---1件: 288
11Alphanate SD/HT1件: Von Willebrand factor human---1件: 288
12ALPHANATE*INF 1F 1000UI+F 10ML1件: Von Willebrand factor human---1件: 288
13ALPHANATE*INF 1F 1500UI+F 10ML1件: Von Willebrand factor human---1件: 288
14ALPHANATE*INF 1F 250UI+F 5ML1件: Von Willebrand factor human---1件: 288
15ALPHANATE*INF 1F 500UI+F 5ML1件: Von Willebrand factor human---1件: 288
16Antihemophilic Factor (Recombinant)----1件: 288
17APCC, aPCC + TXA----1件: 288
18ARC 1779----2件: 64, 288
19ARC1779----2件: 64, 288
20ARC1779 Injection----2件: 64, 288
21BAX 111----1件: 288
22BAX111----1件: 288
23Biostate----1件: 288
24Biostate®----1件: 288
25BIVV001 (rFVIIIFc-VWF-XTEN)----1件: 288
26Blood coagulation Factor VIII and vWF, human1件: Beroctocog alfa---1件: 288
27Blood sample----20件: 8, 13, 46, 49, 51, 53, 61, 66, 84, 88, 96, 97, 107, 127, 235, 274, 280, 288, 294, 299
28BORTEZOMIB1件: Bortezomib1件: D03150 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
29Catridecacog1件: Catridecacog1件: D10532 --2件: 97, 288
30Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
31Cluvot----1件: 288
32Coagadex1件: Coagulation factor X human---1件: 288
33Coagulación factor VIII1件: Beroctocog alfa---1件: 288
34Coagulation factor VIII1件: Beroctocog alfa---1件: 288
35Coagulation factor X1件: Coagulation factor X human---1件: 288
36Coagulation factor XIII1件: Factor XIII (human)---1件: 288
37CoFactor----2件: 265, 288
38Cyclophosphamide1件: Cyclophosphamide2件: D00287 ,
D07760 		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
39DDAVP1件: Desmopressin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 75, 288
40DDAVP (Desmopressin)1件: Desmopressin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬1件: 288
41Desmopressin1件: Desmopressin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬5件: 6, 64, 72, 225, 288
42Desmopressin acetate2件: Acetate,
Desmopressin		1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288
43Desmopressine1件: Desmopressin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 225, 288
44Efanesoctocog alfa1件: Efanesoctocog alfa1件: D12441 --1件: 288
45Emicizumab1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
46Emicizumab (ACE910, RO5534262)1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
47Emicizumab Injection1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
48Eqwilate----1件: 288
49F13CD----1件: 288
50F8VR----1件: 288
51FACTANE 200 IU/ml----1件: 288
52Factor VIII1件: Beroctocog alfa---1件: 288
53Factor VIII concentrate1件: Beroctocog alfa---1件: 288
54Factor von Willebrand1件: Von Willebrand factor human---1件: 288
55FACTOR X1件: Coagulation factor X human---1件: 288
56Factor XIII1件: Factor XIII (human)---3件: 51, 97, 288
57Factor XIII Concentrate (Human)1件: Factor XIII (human)---1件: 288
58Factor XIII Concentrate (Human), Pasteurized1件: Factor XIII (human)---1件: 288
59Fanhdi----1件: 288
60FANHDI 100 UI----1件: 288
61Fanhdi 100 UI FVIII-120 UI FVW----1件: 288
62FANHDI 25 UI----1件: 288
63Fanhdi 25 UI FVIII-30 UI FVW----1件: 288
64FANHDI 250UI*1F 250UI+F 10ML----1件: 288
65FANHDI 50 UI----1件: 288
66Fanhdi 50 UI FVIII-60 UI FVW----1件: 288
67FANHDI*INF FL 250UI+SIR SOLV+S----1件: 288
68FANHDI*INF FL 500UI+SIR SOLV+S----1件: 288
69FANHDI*INF FL1000UI+SIR SOLV+S----1件: 288
70FANHDI*INF FL250UI+SIR SOLV+S----1件: 288
71Fibrogammin P----1件: 288
72Fibrogammin® P----1件: 288
73Fibrogammin®P----1件: 288
74FXIII Concentrate (Human)----1件: 288
75FXIII Concentrate (Human) (FXIII)----1件: 288
76Haemate P----1件: 288
77Haemate P® (Human Coagulation Factor VIII)2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288
78Haemate-P, Wilate1件: Von Willebrand factor human---1件: 288
79Haemate® P 250----1件: 288
80Hemlibra1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
81Hemlibra®1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
82HEMOFIX----1件: 288
83HUMAN COAGULATION FACTOR VIII2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288
84Human coagulation Factor VIII / von Willebrand Factor3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288
85Human coagulation factor VIII associated with Von Willebrand factor (VWF)2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288
86Human Coagulation Factor VIII, Von Willebrand Factor2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288
87HUMAN COAGULATION FACTOR VIII, VON WILLEBRAND FACTOR COMPLEX3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288
88HUMAN COAGULATION FACTOR VIII, VON WILLEBRAND HUMAN COAGULATION FACTOR2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288
89Human Coagulation FACTOR X1件: Coagulation factor X human---1件: 288
90Human factor X1件: Coagulation factor X human---1件: 288
91HUMAN VON WILLEBRAND FACTOR1件: Von Willebrand factor human---1件: 288
92Human von Willebrand factor (VWF) and coagulation factor VIII (FVIII)2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288
93Human VWF/FVIII concentrate----1件: 288
94Humate-P1件: Von Willebrand factor human---1件: 288
95IL-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
96Interleukin 111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
97Interleukin-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬2件: 96, 288
98Marketed plasma-derived VWF/FVIII concentrate----1件: 288
99Minirin1件: Desmopressin1件: D00291 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬2件: 64, 288
100Minrin----1件: 288
101Natriumchlorid1件: Sodium chloride1件: D02056 --1件: 288
102Natriumchlorid 0,9 %1件: Sodium chloride1件: D02056 --1件: 288
103Neumega (Oprelvekin, Interleukin 11, IL-11)1件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
104NN 1841----1件: 288
105NN1841----1件: 288
106OBI-1----1件: 288
107OBIZUR1件: Susoctocog alfa1件: D10831 --1件: 288
108Obyoctocog alfa----1件: 288
109Octanate1件: Beroctocog alfa---1件: 288
110OCTANATE 100 UI/ml, poudre et solvant pour solution injectable1件: Beroctocog alfa---1件: 288
111OCTANATE 50 UI/ml, poudre et solvant pour solution injectable1件: Beroctocog alfa---1件: 288
112OCTOCOG ALFA1件: Antihemophilic factor, human recombinant---1件: 288
113Octostim----2件: 64, 288
114Oprelvekin1件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
115Oprelvekin, Interleukin 11, IL-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
116Optivate----1件: 288
117Optivate® (Human Coagulation Factor VIII)2件: Antihemophilic factor human,
Beroctocog alfa		---1件: 288
118Physiologische Kochsalzlösung Fresenius - Infusionslösung----1件: 288
119Phytomenadione1件: Phylloquinone---1件: 288
120Plasma-derived FVIII/VWF concentrate----1件: 288
121Prednisone1件: Prednisone1件: D00473 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬45件: 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331
122Prothrombin1件: Prothrombin---1件: 288
123Prothrombin Complex Concentrate2件: Factor IX Complex (Human),
Prothrombin		---1件: 288
124RAHF1件: Antihemophilic factor, human recombinant---1件: 288
125Recombinant coagulation FVIII Fc – von Willebrand factor – XTEN fusion protein1件: Von Willebrand factor human---1件: 288
126Recombinant coagulation FVIII Fc –von Willebrand factor – XTEN fusion protein1件: Von Willebrand factor human---1件: 288
127Recombinant factor VIIII (rFVIII)----1件: 288
128Recombinant Factor XIII1件: Factor XIII (human)---1件: 288
129Recombinant Factor XIII (rFXIII)1件: Factor XIII (human)---2件: 97, 288
130RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTO1件: Antihemophilic factor human---1件: 288
131RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288
132RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR - XTEN FUSION PROTEIN2件: Antihemophilic factor human,
Von Willebrand factor human		---1件: 288
133RECOMBINANT HUMAN COAGULATION FACTOR VIII FC - VON WILLEBRAND FACTOR -XTEN FUSION PROTEIN3件: Antihemophilic factor human,
Beroctocog alfa,
Von Willebrand factor human		---1件: 288
134Recombinant human von Willebrand Factor1件: Vonicog alfa1件: D08681 --1件: 288
135Recombinant interleukin-111件: Oprelvekin1件: D05266 1件: IL11RA 💬3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬1件: 288
136Recombinant porcine coagulation factor VIII (B domain deleted)1件: Beroctocog alfa---1件: 288
137Recombinant porcine coagulation factor VIII (B-domain deleted)1件: Beroctocog alfa---1件: 288
138Recombinant von Willebrand Factor1件: Von Willebrand factor human---1件: 288
139Recombinant von Willebrand Factor (rVWF)1件: Von Willebrand factor human---1件: 288
140Recombinant von Willebrand Factor 1300IU1件: Vonicog alfa1件: D08681 --1件: 288
141Recombinant von Willebrand Factor 650IU1件: Vonicog alfa1件: D08681 --1件: 288
142Recombinant von Willebrand factor : recombinant FVIII (rVWF:rFVIII)1件: Von Willebrand factor human---1件: 288
143Recomibnant human Von Willebrand Factor1件: Vonicog alfa1件: D08681 --1件: 288
144RFVIIa1件: Coagulation factor VIIa Recombinant Human---1件: 288
145RFVIIa, rFVIIa + TXA1件: Coagulation factor VIIa Recombinant Human---1件: 288
146RFVIII----1件: 288
147Rituxan----4件: 46, 60, 256, 288
148RITUXIMAB1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
149RO5534262 EMICIZUMAB1件: Emicizumab1件: D10821 2件: F10,
F9 💬		1件: Complement and coagulation cascades 💬1件: 288
150Rurioctocog alfa pegol1件: Rurioctocog alfa pegol1件: D10760 --1件: 288
151RVWF----1件: 288
152Saline solution----4件: 2, 34, 288, 299
153Simvastatin1件: Simvastatin1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
154Simvastatine1件: Simvastatin1件: D00434 1件: HMGCR 💬4件: AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 6, 13, 288
155Sodium chloride2件: Chloride ion,
Sodium chloride		1件: D02056 --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
156SODIUM CHLORIDE SOLUTION 0.9%2件: Chloride ion,
Sodium chloride		1件: D02056 --4件: 51, 60, 288, 299
157Standard of Care for Haemophilia A----1件: 288
158Standard of Care FVIII Replacement therapy----1件: 288
159Steroid----2件: 107, 288
160TAK-672----1件: 288
161Tranexamic acid1件: Tranexamic acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬7件: 46, 70, 215, 227, 274, 288, 299
162VEYONDI 650IU powder and solvent for solution for injection----1件: 288
163Veyvondi1件: Vonicog alfa1件: D08681 --1件: 288
164VEYVONDI 1300 IU powder and solvent for solution for injection1件: Vonicog alfa1件: D08681 --1件: 288
165VEYVONDI 1300I IU powder and solvent for solution for injection1件: Vonicog alfa1件: D08681 --1件: 288
166VEYVONDI 1300IU powder and solvent for solution for injection1件: Vonicog alfa1件: D08681 --1件: 288
167VEYVONDI 650IU powder and solvent for solution for injection1件: Vonicog alfa1件: D08681 --1件: 288
168Von willebrand factor1件: Von Willebrand factor human---2件: 64, 288
169Von Willebrand factor (Recombinant)1件: Von Willebrand factor human---1件: 288
170Von Willebrand factor and coagulation factor VIII in combination2件: Beroctocog alfa,
Von Willebrand factor human		---1件: 288
171Von Willebrand Factor Antigen1件: Von Willebrand factor human---1件: 288
172Von Willebrand Factor Ristocetin Cofactor1件: Von Willebrand factor human---1件: 288
173Von Willebrand Faktor----1件: 288
174Voncento1件: Von Willebrand factor human---1件: 288
175Voncento, Biostate®1件: Von Willebrand factor human---1件: 288
176Voncento®1件: Von Willebrand factor human---1件: 288
177VONICOG ALFA1件: Vonicog alfa1件: D08681 --1件: 288
178VWD factor VIII concentrate1件: Beroctocog alfa---1件: 288
179VWF gene analysis----1件: 288
180VWF replacement therapy with Wilate1件: Von Willebrand factor human---1件: 288
181VWF SD-35-DH----1件: 288
182VWF-containing products----1件: 288
183VWF/FVIII products----1件: 288
184WILATE1件: Von Willebrand factor human---1件: 288
185Wilate 10001件: Von Willebrand factor human---1件: 288
186WILATE 1000 I.U.1件: Von Willebrand factor human---1件: 288
187WILATE 4501件: Von Willebrand factor human---1件: 288
188Wilate 5001件: Von Willebrand factor human---1件: 288
189WILATE 500 I.U.1件: Von Willebrand factor human---1件: 288
190WILATE 9001件: Von Willebrand factor human---1件: 288
191WILATE® 4501件: Von Willebrand factor human---1件: 288
192WILFACTIN----1件: 288
193Willfact----1件: 288
194Wiloctin----1件: 288