Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	F8	1件: Complement and coagulation cascades	D00291	Desmopressin	1件: 288
2	F9	1件: Complement and coagulation cascades	D10821	Emicizumab	1件: 288
3	F10	1件: Complement and coagulation cascades	D10821	Emicizumab	1件: 288
4	NR3C1	1件: Neuroactive ligand-receptor interaction	D00473	Prednisone	5件: 288, 299, 300, 307, 331
5	HMGCR	4件: Terpenoid backbone biosynthesis, Metabolic pathways, AMPK signaling pathway, Bile secretion	D00434	Simvastatin	21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310
6	IL11RA	3件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage	D05266	Oprelvekin	2件: 96, 288
7	PLG	4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aur ...	D01136	Tranexamic acid	7件: 46, 70, 215, 227, 274, 288, 299
8	AVPR2	3件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vasopressin-regulate ...	D00291	Desmopressin	6件: 6, 64, 72, 75, 225, 288
9	PSMB5	8件: Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington dise ...	D03150	Bortezomib	17件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331
10	MS4A1	1件: Hematopoietic cell lineage	D02994	Rituximab	4件: 288, 296, 300, 331

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