Leuprorelin Acetate ( DrugBank: Leuprorelin, Acetate )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
1	球脊髄性筋萎縮症	7
76	下垂体性ゴナドトロピン分泌亢進症	6

1. 球脊髄性筋萎縮症

臨床試験数 : 18 / 薬物数 : 15 - (DrugBank : 8) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 17

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-JapicCTI-183981	02/11/2017	01/06/2018	Specified Drug-Use Survey of Leuprorelin AcetateInjection Kit 11.25 mg All-Case Investigation: Spina ...	Specified Drug-Use Survey of Leuprorelin AcetateInjection Kit 11.25 mg All-Case Investigation: Spina ...	Spinal and bulbar muscular atrophy	Intervention name : Leuprorelin Acetate Dosage And administration of the intervention : Leuprorelin A ...	TAKEDA PHARMACEUTICAL COMPANY LTD.	NULL	recruiting			BOTH	300	NA	NULL
2	NCT03555578 (ClinicalTrials.gov)	November 2, 2017	1/6/2018	Specified Drug-Use Survey of Leuprorelin AcetateInjection Kit 11.25 mg All-Case Investigation: Spina ...	Specified Drug-Use Survey of Leuprorelin AcetateInjection Kit 11.25 mg All-Case Investigation: Spina ...	Spinal and Bulbar Muscular Atrophy	Drug: Leuprorelin Acetate	Takeda	NULL	Recruiting	N/A	N/A	All	300		Japan
3	JPRN-JMA-IIA00080	02/2012	26/01/2012	Phase 2 Clinical Trial of Leuprorelin acetate in patients with SBMA (JASMITT-2)	Double-blind Placebo-controlled Phase 2 Clinical Trial of TAP-144-SR (3M) in patients with Spinal an ...	Spinal and Bulbar muscular atrophy	Intervention type:DRUG. Intervention1:TAP-144-SR(3M) , Dose form:INJECTION, Route of administration: ...	JASMITT Clinical Trial Office	Jichi med college, Chiba univ., Univ of Tokyo, Tokyo med & dental univ.	Completed	>=30 YEARS	<70 YEARS	Male	100	Phase 2	Japan
4	JPRN-UMIN000001455	2008/10/01	23/10/2008	Open clinical trial of Leuprorelin Acetate (SR) in patients with Kennedy-Alter-Sung syndrome (KAS)	Open clinical trial of Leuprorelin Acetate(SR) in patients with Kennedy-Alter-Sung syndrome (KAS) - ...	Kennedy-Alter-Sung syndrome (KAS)	Leuprorelin acetate (SR) 11.25mg subcutaneous infection per 12 weeks	Department of NeurologyChiba University Graduate School of Medicine	NULL		20years-old	Not applicable	Male	10	Not selected	Japan
5	JPRN-JMA-IIA00111	29/08/2007	22/02/2013	Long Term Follow-up Phase III Clinical Trial of Leuprorelin acetate in Patients with SBMA (JASMITT)	Long Term Follow-up Phase III Clinical Trial of TAP-144-SR (3M) in Patients with Spinal and Bulbar M ...	Spinal and Bulbar Muscular Atrophy (SBMA)	Intervention type:DRUG. Intervention1:TAP-144-SR(3M), Dose form:INJECTION, Route of administration:S ...	Gen Sobue	Ichiro Yabe, Masashi Aoki, Imaharu Nakano, Kazuaki Kanai, Hidehiro Mizusawa, Tomotaka Yamamoto, Kazu ...	Completed	>=30 YEARS	<71 YEARS	Male	152	Phase 3	Japan
6	JPRN-JMA-IIA00009	13/09/2006	24/08/2006	Phase III Clinical Trial of Leuprorelin acetate in Patients with SBMA (JASMITT)	Double-blind Placebo-controlled Phase III Clinical Trial of TAP-144-SR (3M) in Patients with Spinal ...	Spinal and Bulbar Muscular Atrophy (SBMA)	Intervention type:DRUG. Intervention1:TAP-144-SR(3M), Dose form:INJECTION, Route of administration:S ...	JASMITT Clinical Trial Office	Hokkaido University, Tohoku University, Jichi Medical College, Chiba University, University of Tokyo ...	Completed	>=30 YEARS	<70 YEARS	Male	170	Phase 3	Japan
7	JPRN-UMIN000000474	2003/09/01	01/09/2006	Double-blind Placebo-controlled Clinical Trial of Leuprorelin acetatein Patients with Spinal and Bul ...	Double-blind Placebo-controlled Clinical Trial of Leuprorelin acetatein Patients with Spinal and Bul ...	Spinal and bulbar muscular atrophy (SBMA)	Leuprorelin acetate3.75 mg subcutaneous injection every 4 weeks Placebo subcutaneous injection every ...	Department of Neurology, Nagoya University School of Medicine	NULL	Complete: follow-up complete	30years-old	70years-old	Male	40	Phase 2	Japan

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76. 下垂体性ゴナドトロピン分泌亢進症

臨床試験数 : 29 / 薬物数 : 44 - (DrugBank : 14) / 標的遺伝子数 : 5 - 標的パスウェイ数 : 15

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05341115 (ClinicalTrials.gov)	March 20, 2023	18/4/2022	A Study of Leuprolide Acetate Depot in Children With Central Precocious Puberty	An Open Label, Multicenter, Single-arm and Prospective Study to Assess the Efficacy and Safety of Le ...	Central Precocious Puberty	Drug: Leuprorelin Acetate Depot 3M	Takeda	NULL	Not yet recruiting	N/A	9 Years	All	80	Phase 4	China
2	NCT03963752 (ClinicalTrials.gov)	August 15, 2019	22/5/2019	Clinical Trial of Rapid Progressive Central Precocious Puberty With Integrative Chinese and Western ...	Evidence-based Medical Research on the Treatment of Children's Rapid Progressive Central Precocious ...	Idiopathic Precocious Puberty	Drug: Ziyinxiehuo Granules Herbs;Drug: Megestrol Acetate Tablet;Drug: Leuprorelin Acetate3.75mg Inje ...	Children's Hospital of Fudan University	NULL	Recruiting	5 Years	8 Years	Female	164	Phase 4	China
3	NCT03316482 (ClinicalTrials.gov)	June 11, 2015	12/10/2017	Leuprorelin AcetateDPS (Leuplin DPS) Treatment Quarterly in Patients With Central Precocious Puberty ...	A Multicenter, Open, Prospective Study to Evaluate the Safety and Efficacy of Leuprorelin AcetateDPS ...	Central Precocious Puberty	Drug: Leuplin DPS 11.25mg	Jin Soon Hwang	NULL	Completed	4 Years	9 Years	All	58	Phase 4	Korea, Republic of
4	EUCTR2014-004495-36-Outside-EU/EEA (EUCTR)		28/11/2014	A study of Lupron Depot Lupron Depot in treatment of central premature puberty	Study of Lupron Depot in the Treatment of Central Precocious Puberty	Central Precocious Puberty MedDRA version: 17.1;Level: LLT;Classification code 10073186;Term: Centra ...	Trade Name: trade name depends on the source of the product INN or Proposed INN: LEUPRORELIN ACETATE T ...	Abbvie previously known as Abbott	NULL	NA			Female: yes Male: yes	55		United States
5	EUCTR2014-004494-16-Outside-EU/EEA (EUCTR)		03/12/2014	A clinical trial to determine safety and efficacy of Leuprolide Acetate 11.25mg and 30mg in children ...	A 36 Month, Multi-Center, Open-Label Extension Study to Evaluate theSafety of Leuprolide Acetate 11. ...	Central Precocious Puberty MedDRA version: 17.1;Level: LLT;Classification code 10073186;Term: Centra ...	Trade Name: trade name depends on the source of the product INN or Proposed INN: LEUPRORELIN ACETATE T ...	Abbvie previously known as Abbott	NULL	NA			Female: yes Male: yes	72		United States;Puerto Rico
6	EUCTR2014-004493-42-Outside-EU/EEA (EUCTR)		03/12/2014	A clinical trial to determine safety and efficacy of Leuprolide Acetate 11.25mg and 30mg in children ...	A Phase 3, Randomized, Multi-Center, Open-Label Study to Evaluate theEfficacy and Safety of Leuproli ...	Central Precocious Puberty MedDRA version: 17.1;Level: LLT;Classification code 10073186;Term: Centra ...	Trade Name: trade name depends on the source of the product Product Name: Leuprolide acetate depot INN ...	Abbvie previously known as Abbott	NULL	NA			Female: yes Male: yes	80	Phase 3	United States;Puerto Rico

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