Flurbiprofen ( DrugBank: Flurbiprofen )

3 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
13	多発性硬化症／視神経脊髄炎	1
21	ミトコンドリア病	1
46	悪性関節リウマチ	3

13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2014-004483-38-DE (EUCTR)	16/07/2015	28/04/2015	TMP001 in relapsing-remitting multiple sclerosis: a multicentre open, baseline-controlled phase IIa ...	TMP001 in relapsing-remitting multiple sclerosis: a multicentre open, baseline-controlled phase IIa ...	Patients with defined diagnosis of relapsing-remitting multiple sclerosis and at least 1 documented ...	Product Name: Tarenflurbil Product Code: TMP001 INN or Proposed INN: Tarenflurbil Other descriptive nam ...	Fraunhofer Gesellschaft for its Institute Fraunhofer Institute for Molecular Biology and Applied Eco ...	NULL	Not Recruiting			Female: yes Male: yes	55	Phase 2	Germany

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21. ミトコンドリア病

臨床試験数 : 39 / 薬物数 : 42 - (DrugBank : 32) / 標的遺伝子数 : 47 - 標的パスウェイ数 : 67

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04643249 (ClinicalTrials.gov)	November 10, 2020	13/11/2020	Drug-drug Interaction Study of KL1333 in Healthy Subjects	A Phase I, Open-label, Fixed-sequence, Crossover, Drug-drug Interaction Study to Investigate the Inh ...	Mitochondrial Disease	Drug: KL1333;Drug: Flurbiprofen;Drug: Dextromethorphan;Drug: Bupropion;Drug: Midazolam injection;Dru ...	Abliva AB	NULL	Completed	18 Years	65 Years	All	14	Phase 1	United Kingdom

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46. 悪性関節リウマチ

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03131973 (ClinicalTrials.gov)	May 13, 2017	25/4/2017	Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbipr ...	Effects of Concomitant Administration of BMS-986195 on the Single-dose Pharmacokinetics of Methotrex ...	Rheumatoid Arthritis	Drug: BMS-986195;Drug: Methotrexate;Drug: Leucovorin;Drug: Caffeine;Drug: Montelukast;Drug: Flurbipr ...	Bristol-Myers Squibb	NULL	Completed	18 Years	50 Years	All	26	Phase 1	United States
2	NCT02762123 (ClinicalTrials.gov)	May 2016	3/5/2016	A Study to Assess the Effect of BMS-986142 on Pharmacokinetics (PK) of Probe Substrates	Effects of Concomitant Administration of BMS-986142 on the Single-dose Pharmacokinetics of Probe Sub ...	Rheumatoid Arthritis	Drug: BMS-986142 200mg;Drug: BMS Drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazo ...	Bristol-Myers Squibb	NULL	Completed	18 Years	50 Years	Both	28	Phase 1	United States
3	NCT02456844 (ClinicalTrials.gov)	May 2015	27/5/2015	Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe ...	Effects of BMS-986142 on the Single-dose Pharmacokinetics of Methotrexate and Probe Substrates Monte ...	Rheumatoid Arthritis	Drug: Montelukast, Flurbiprofen, Midazolam, Digoxin, Pravastatin and BMS-986142;Drug: Methotrexate, ...	Bristol-Myers Squibb	NULL	Completed	18 Years	50 Years	Both	24	Phase 1	NULL

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