Target Gene/Pathway Pathway / Gene

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No.	KEGG GENES	KEGG PATHWAY	KEGG DRUG	DrugBank	指定難病告示番号
1	SIGMAR1	2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases	D03742	Dextromethorphan	11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
3	ADORA1	7件: cGMP-PKG signaling pathway, cAMP signaling pathway, Sphingolipid signaling pathway, Neuroactive ...	D01453	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
4	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D00528	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
5	ADORA2A	7件: Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-re ...	D01453	Caffeine	8件: 2, 6, 21, 46, 78, 96, 97, 265
6	ADRA2A	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
7	ADRA2B	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
8	ADRA2C	2件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction	D00514	Dexmedetomidine	14件: 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280
9	DRD2	8件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Gap jun ...	D09997	Cariprazine	1件: 21
10	GABRA1	6件: Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse ...	D00549	Propofol	9件: 6, 21, 22, 34, 46, 70, 75, 98, 296

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