Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | ABC transporters 💬 Related to 3 target genes, 10 drugs (DrugBank) and 8 diseases in DDrare |
ABCC8 1件: ABCC8 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
2 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
3 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
4 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
5 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
6 | Alcoholism 💬 Related to 28 target genes, 75 drugs (DrugBank) and 53 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
7 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
8 | Aldosterone synthesis and secretion 💬 Related to 20 target genes, 38 drugs (DrugBank) and 62 diseases in DDrare |
PDE2A 1件: PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
9 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
10 | Alzheimer disease 💬 Related to 55 target genes, 116 drugs (DrugBank) and 122 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
11 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
12 | Amphetamine addiction 💬 Related to 25 target genes, 51 drugs (DrugBank) and 91 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
13 | Amyotrophic lateral sclerosis 💬 Related to 35 target genes, 48 drugs (DrugBank) and 108 diseases in DDrare |
GRIN1 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
14 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
15 | Apelin signaling pathway 💬 Related to 12 target genes, 30 drugs (DrugBank) and 72 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
16 | Arachidonic acid metabolism 💬 Related to 4 target genes, 26 drugs (DrugBank) and 43 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
17 | C-type lectin receptor signaling pathway 💬 Related to 26 target genes, 64 drugs (DrugBank) and 99 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
18 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADORA2A 2件: ADORA2A, PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
19 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
ADORA2A 2件: ADORA2A, PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
20 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
GRIN1 4件: GRIN1, GRIN2A, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
21 | Calcium signaling pathway 💬 Related to 79 target genes, 187 drugs (DrugBank) and 134 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
22 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
23 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
24 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
DRD2 2件: DRD2, HTR1A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
25 | cAMP signaling pathway 💬 Related to 67 target genes, 171 drugs (DrugBank) and 114 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
26 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
27 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
28 | cGMP-PKG signaling pathway 💬 Related to 46 target genes, 119 drugs (DrugBank) and 118 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
29 | Chemical carcinogenesis - DNA adducts 💬 Related to 1 target gene, 24 drugs (DrugBank) and 40 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
30 | Circadian entrainment 💬 Related to 22 target genes, 32 drugs (DrugBank) and 55 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
31 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
32 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
33 | Cocaine addiction 💬 Related to 15 target genes, 63 drugs (DrugBank) and 52 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
34 | Collecting duct acid secretion 💬 Related to 3 target genes, 11 drugs (DrugBank) and 35 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
35 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
36 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
37 | Dopaminergic synapse 💬 Related to 31 target genes, 99 drugs (DrugBank) and 101 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
38 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
39 | GABAergic synapse 💬 Related to 29 target genes, 38 drugs (DrugBank) and 55 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
40 | Gap junction 💬 Related to 26 target genes, 87 drugs (DrugBank) and 77 diseases in DDrare |
DRD2 2件: DRD2, HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
41 | Gastric acid secretion 💬 Related to 14 target genes, 43 drugs (DrugBank) and 52 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
42 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
43 | Glucagon signaling pathway 💬 Related to 12 target genes, 19 drugs (DrugBank) and 83 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
44 | Glutamatergic synapse 💬 Related to 23 target genes, 27 drugs (DrugBank) and 83 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
45 | GnRH secretion 💬 Related to 20 target genes, 42 drugs (DrugBank) and 54 diseases in DDrare |
KCNJ11 1件: KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
46 | Human cytomegalovirus infection 💬 Related to 56 target genes, 104 drugs (DrugBank) and 120 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
47 | Human papillomavirus infection 💬 Related to 40 target genes, 91 drugs (DrugBank) and 105 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
48 | Huntington disease 💬 Related to 24 target genes, 33 drugs (DrugBank) and 82 diseases in DDrare |
GRIN1 2件: GRIN1, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
49 | IL-17 signaling pathway 💬 Related to 20 target genes, 60 drugs (DrugBank) and 83 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
50 | Inflammatory mediator regulation of TRP channels 💬 Related to 23 target genes, 43 drugs (DrugBank) and 59 diseases in DDrare |
HTR2A 1件: HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
51 | Insulin secretion 💬 Related to 14 target genes, 39 drugs (DrugBank) and 44 diseases in DDrare |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
52 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
53 | Insulin signaling pathway 💬 Related to 12 target genes, 26 drugs (DrugBank) and 66 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
54 | Kaposi sarcoma-associated herpesvirus infection 💬 Related to 50 target genes, 84 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
55 | Leishmaniasis 💬 Related to 25 target genes, 63 drugs (DrugBank) and 93 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
56 | Long-term potentiation 💬 Related to 18 target genes, 33 drugs (DrugBank) and 86 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
57 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
58 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
59 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
60 | Metabolic pathways 💬 Related to 111 target genes, 155 drugs (DrugBank) and 137 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
61 | MicroRNAs in cancer 💬 Related to 31 target genes, 65 drugs (DrugBank) and 85 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
62 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
63 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
64 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
65 | Morphine addiction 💬 Related to 41 target genes, 65 drugs (DrugBank) and 73 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
66 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
67 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADORA1 2件: ADORA1, ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
68 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
ADRA2A 3件: ADRA2A, ADRA2B, ADRA2C 💬 |
D00514 D00514 💬 |
Dexmedetomidine | 002 14件: 2 , 4 , 6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬 |
69 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
DRD2 3件: DRD2, HTR1A, HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
70 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
71 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
72 | Neuroactive ligand-receptor interaction 💬 Related to 149 target genes, 320 drugs (DrugBank) and 153 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
73 | NF-kappa B signaling pathway 💬 Related to 20 target genes, 67 drugs (DrugBank) and 87 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
74 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
75 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
76 | Nicotine addiction 💬 Related to 30 target genes, 30 drugs (DrugBank) and 44 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
77 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 13 diseases in DDrare |
PDE1B 2件: PDE1B, PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
78 | Olfactory transduction 💬 Related to 4 target genes, 5 drugs (DrugBank) and 13 diseases in DDrare |
PDE1B 2件: PDE1B, PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
79 | Ovarian steroidogenesis 💬 Related to 7 target genes, 36 drugs (DrugBank) and 52 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
80 | Oxidative phosphorylation 💬 Related to 2 target genes, 7 drugs (DrugBank) and 25 diseases in DDrare |
ATP4A 2件: ATP4A, ATP4B 💬 |
D00455 D00455 💬 |
Omeprazole | 006 14件: 6 , 8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬 |
81 | Oxytocin signaling pathway 💬 Related to 34 target genes, 73 drugs (DrugBank) and 108 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
82 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
83 | Parathyroid hormone synthesis, secretion and action 💬 Related to 21 target genes, 48 drugs (DrugBank) and 65 diseases in DDrare |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
84 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
85 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
86 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
87 | Parkinson disease 💬 Related to 24 target genes, 73 drugs (DrugBank) and 66 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
88 | Pathways in cancer 💬 Related to 104 target genes, 194 drugs (DrugBank) and 133 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
89 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
GRIN1 6件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
90 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
91 | Pathways of neurodegeneration - multiple diseases 💬 Related to 59 target genes, 120 drugs (DrugBank) and 125 diseases in DDrare |
SLC6A3 1件: SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
92 | Platelet activation 💬 Related to 22 target genes, 51 drugs (DrugBank) and 56 diseases in DDrare |
PTGS1 1件: PTGS1 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
93 | Prion disease 💬 Related to 41 target genes, 66 drugs (DrugBank) and 107 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
94 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
95 | Progesterone-mediated oocyte maturation 💬 Related to 14 target genes, 38 drugs (DrugBank) and 42 diseases in DDrare |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
96 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
97 | Purine metabolism 💬 Related to 29 target genes, 35 drugs (DrugBank) and 73 diseases in DDrare |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
98 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
99 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
100 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
DRD2 1件: DRD2 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
101 | Rap1 signaling pathway 💬 Related to 42 target genes, 101 drugs (DrugBank) and 85 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
102 | Ras signaling pathway 💬 Related to 35 target genes, 53 drugs (DrugBank) and 62 diseases in DDrare |
GRIN1 3件: GRIN1, GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
103 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
104 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
ADORA1 2件: ADORA1, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
105 | Regulation of lipolysis in adipocytes 💬 Related to 13 target genes, 71 drugs (DrugBank) and 69 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
106 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
107 | Renin secretion 💬 Related to 28 target genes, 82 drugs (DrugBank) and 107 diseases in DDrare |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
108 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
109 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
110 | Retrograde endocannabinoid signaling 💬 Related to 34 target genes, 62 drugs (DrugBank) and 67 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
111 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
112 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
GABRB1 3件: GABRB1, GABRB2, GABRB3 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
113 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
HTR1A 2件: HTR1A, HTR2A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
114 | Serotonergic synapse 💬 Related to 38 target genes, 112 drugs (DrugBank) and 79 diseases in DDrare |
PTGS1 2件: PTGS1, PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
115 | Small cell lung cancer 💬 Related to 14 target genes, 39 drugs (DrugBank) and 59 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
116 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
117 | Sphingolipid signaling pathway 💬 Related to 30 target genes, 52 drugs (DrugBank) and 73 diseases in DDrare |
ADORA1 1件: ADORA1 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
118 | Spinocerebellar ataxia 💬 Related to 17 target genes, 25 drugs (DrugBank) and 70 diseases in DDrare |
GRIN1 5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
119 | Synaptic vesicle cycle 💬 Related to 7 target genes, 30 drugs (DrugBank) and 40 diseases in DDrare |
SLC6A2 2件: SLC6A2, SLC6A3 💬 |
D07591 D07591 💬 |
Bupropion | 008 5件: 8 , 18, 21, 96, 171 💬 |
120 | Systemic lupus erythematosus 💬 Related to 14 target genes, 38 drugs (DrugBank) and 78 diseases in DDrare |
GRIN2A 2件: GRIN2A, GRIN2B 💬 |
D03742 D03742 💬 |
Dextromethorphan | 002 11件: 2 , 6 , 8 , 13, 21, 46, 78, 85, 96, 97, 156 💬 |
121 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00550 D00550 💬 |
Midazolam | 002 12件: 2 , 3 , 6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬 |
122 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
GABRA1 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00549 D00549 💬 |
Propofol | 006 9件: 6 , 21, 22, 34, 46, 70, 75, 98, 296 💬 |
123 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
HTR1A 1件: HTR1A 💬 |
D09997 D09997 💬 |
Cariprazine | 021 1件: 21 💬 |
124 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
PDE1B 1件: PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
125 | Taste transduction 💬 Related to 30 target genes, 81 drugs (DrugBank) and 65 diseases in DDrare |
PDE1B 1件: PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
126 | TNF signaling pathway 💬 Related to 18 target genes, 56 drugs (DrugBank) and 84 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |
127 | Type II diabetes mellitus 💬 Related to 14 target genes, 39 drugs (DrugBank) and 91 diseases in DDrare |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00594 D00594 💬 |
Repaglinide | 006 4件: 6 , 21, 46, 299 💬 |
128 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
129 | Vascular smooth muscle contraction 💬 Related to 31 target genes, 77 drugs (DrugBank) and 68 diseases in DDrare |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 |
130 | VEGF signaling pathway 💬 Related to 21 target genes, 53 drugs (DrugBank) and 90 diseases in DDrare |
PTGS2 1件: PTGS2 💬 |
D00330 D00330 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 |