Domperidone ( DrugBank: Domperidone )

5 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
6	パーキンソン病	6
13	多発性硬化症／視神経脊髄炎	2
17	多系統萎縮症	1
51	全身性強皮症	1
230	肺胞低換気症候群	1

6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03022201 (ClinicalTrials.gov)	May 2013	23/11/2016	Comparing the Therapeutic Efficacy and Safety of DA-9701 With Domperidonein Patients With Parkinson' ...	Therapeutic Efficacy of DA-9701 on Gastric Motility in Patients With Parkinson's Disease Evaluated b ...	Parkinson's Disease,Idiopathic	Drug: DA-9701;Drug: Domperidone;Drug: Placebo domperidone;Drug: Placebo DA-9701	Seoul National University Hospital	NULL	Completed	20 Years	80 Years	All	40	Phase 4	Korea, Republic of
2	NCT02500108 (ClinicalTrials.gov)	May 2013	14/7/2015	Domperidone and Risk of Sudden Cardiac Death	Domperidone Use in Parkinson's Disease and Risk of Sudden Cardiac Death	Parkinson's Disease	Drug: Domperidone	Canadian Network for Observational Drug Effect Studies, CNODES	Drug Safety and Effectiveness Network, Canada;Canadian Institutes of Health Research (CIHR)	Completed	50 Years	N/A	Both	214962	N/A	Canada
3	JPRN-UMIN000007896	2012/05/01	07/05/2012	Levodopa challenge test for Parkinson's disease and other parkinsonian syndromes	Levodopa challenge test for Parkinson's disease and other parkinsonian syndromes - Levodopa challeng ...	Parkinson's disease and other parkinsonian syndromes	The patients are given domperidone30 mg/day for 3 days. When a patient is already on any anti-parkin ...	Kansai Medical University	NULL	Recruiting	Not applicable	Not applicable	Male and Female	100	Not selected	Japan
4	NCT00305331 (ClinicalTrials.gov)	March 2006	20/3/2006	Domperidoneas a Treatment for Dopamine Agonist-induced Peripheral Edema in Patients With Parkinson's ...	Phase II Clinical Trial of Domperidoneas a Treatment for Dopamine Agonist-induced Peripheral Edema i ...	Parkinson's Disease;Peripheral Edema	Drug: Domperidone (drug)	University Health Network, Toronto	NULL	Terminated	30 Years	90 Years	Both	25	Phase 2	Canada
5	NCT00103597 (ClinicalTrials.gov)	January 2005	11/2/2005	Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multipl ...	Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multipl ...	Parkinson's Disease;Multiple System Atrophy;Orthostatic Hypotension	Drug: Fludrocortisone;Drug: Domperidone;Behavioral: Conservative Measures for Orthostatic Hypotensio ...	Royal Brisbane and Women's Hospital	NULL	Completed	40 Years	95 Years	Both	50	Phase 1	Australia
6	NCT00006077 (ClinicalTrials.gov)	August 2000	4/8/2000	Effects of Monoamine Reuptake Inhibitor NS2330 in Parkinson's Disease	Effects of Monoamine Reuptake Inhibitor NS2330 in Parkinson's Disease	Parkinson's Disease	Drug: NS2330;Drug: Levodopa and Domperidone	National Institute of Neurological Disorders and Stroke (NINDS)	NULL	Completed	N/A	N/A	Both	50	Phase 2	United States

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13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02493049 (ClinicalTrials.gov)	August 2015	2/7/2015	Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis (RRMS)	Randomized, Controlled Pilot Trial of Domperidone in Relapsing-Remitting Multiple Sclerosis	Multiple Sclerosis, Relapsing-Remitting	Drug: Domperidone	University of Calgary	Alberta Innovates Health Solutions	Completed	18 Years	60 Years	All	17	Phase 2	Canada
2	NCT02308137 (ClinicalTrials.gov)	February 2015	2/12/2014	Domperidone in Secondary Progressive Multiple Sclerosis (SPMS)	Open-label, Single-center, Single-arm Futility Trial Evaluating Oral Domperidone10mg QID for Reducin ...	Multiple Sclerosis, Secondary Progressive	Drug: Domperidone	University of Calgary	Alberta Innovates Health Solutions	Completed	18 Years	60 Years	All	64	Phase 2	Canada

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17. 多系統萎縮症

臨床試験数 : 119 / 薬物数 : 138 - (DrugBank : 44) / 標的遺伝子数 : 59 - 標的パスウェイ数 : 111

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00103597 (ClinicalTrials.gov)	January 2005	11/2/2005	Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multipl ...	Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multipl ...	Parkinson's Disease;Multiple System Atrophy;Orthostatic Hypotension	Drug: Fludrocortisone;Drug: Domperidone;Behavioral: Conservative Measures for Orthostatic Hypotensio ...	Royal Brisbane and Women's Hospital	NULL	Completed	40 Years	95 Years	Both	50	Phase 1	Australia

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51. 全身性強皮症

臨床試験数 : 525 / 薬物数 : 565 - (DrugBank : 148) / 標的遺伝子数 : 114 - 標的パスウェイ数 : 217

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01878526 (ClinicalTrials.gov)	June 2013	7/6/2013	Gastroesophageal Reflux Treatment in Scleroderma	The Effectiveness of DomperidoneVersus Alginic Acid Add on Omeprazole Therapy in Omeprazole Resistan ...	Gastroesophageal Reflux Disease;Systemic Sclerosis;Scleroderma	Drug: Alginic acid;Drug: placebo (for domperidone);Drug: Domperidone;Drug: placebo (of alginic acid) ...	Khon Kaen University	NULL	Completed	18 Years	65 Years	All	80	Phase 3	Thailand

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230. 肺胞低換気症候群

臨床試験数 : 6 / 薬物数 : 7 - (DrugBank : 4) / 標的遺伝子数 : 16 - 標的パスウェイ数 : 26

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2005-005950-33-SE (EUCTR)	07/06/2006	10/04/2006	Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1	Studie av Domperidon och barn med kongenitalt centralt hypoventilationssyndrom. - DOMPCCHSSWE1	Congenital central hypoventilation syndrome, CCHS or Ondine's curse.	Trade Name: Motilium Product Name: Motilium INN or Proposed INN: Domperidone	Karolinska Universitetssjukhuset	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Sweden

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