Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ampreloxetine 1件: Ampreloxetine1件: D11688 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬2件: 6, 17
2 Angiotensin II 2件: Angiotensin; Angiotensin II2件: D00150 ,
D02014 		2件: AGTR1,
AGTR2 💬		16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 17, 19, 46, 66, 86, 222, 224
3 Atomoxetine 2件: Atomoxetine; Strattera1件: D07473 1件: SLC6A2 💬1件: Synaptic vesicle cycle 💬4件: 6, 8, 13, 17
4 Botulinum toxin type A 8件: Botox; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬14件: 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226
5 BQ-123 0件: ---1件: 17
6 Captopril 1件: Captopril1件: D00251 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬8件: 6, 17, 46, 86, 96, 97, 107, 271
7 Carbidopa 8件: Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00558 1件: DDC 💬9件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬7件: 6, 13, 17, 90, 140, 164, 201
8 Carbonate ion 1件: Carbonate---12件: 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
9 Domperidone 1件: Domperidone2件: D01745 ,
D07868 		1件: DRD2 💬8件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 13, 17, 51, 230
10 Droxidopa 4件: DOPS; Droxidopa; L-DOPS; Northera1件: D01277 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬5件: 5, 6, 17, 169, 170
11 Emeramide 1件: Emeramide---2件: 5, 17
12 Entacapone 5件: COMTAN; Comtess; ENTACAPONA; Entacapone; Stalevo1件: D00781 1件: COMT 💬4件: Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬2件: 6, 17
13 Epigallocatechin gallate 3件: EGCG; Epigallocatechin gallate; Epigallocatechin-3-gallate---9件: 6, 8, 13, 17, 28, 85, 113, 206, 299
14 Exenatide 3件: Bydureon; Byetta; Exenatide1件: D04121 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233
15 Fipamezole 1件: Fipamezole---2件: 6, 17
16 Fludrocortisone 1件: Fludrocortisone1件: D07967 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬3件: 6, 17, 81
17 Flumazenil 1件: Flumazenil1件: D00697 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206
18 Fluoxetine 5件: Fluoxetin; FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC1件: D00326 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
19 Gold 1件: Gold---43件: 2, 5, 6, 13, 17, 34, 35, 46, 49, 50, 53, 58, 63, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 137, 158, 162, 167, 171, 193, 218, 222, 224, 226, 227, 230, 271, 291, 296, 298, 310, 318
20 Green tea leaf 4件: Green Tea; Green Tea Extract; GREEN TEA LEAF; Tea Extract1件: D06903 --4件: 6, 17, 28, 46
21 Human immunoglobulin G 19件: Bivigam; CUTAQUIG; CUVITRU; GAMMAGARD LIQUID; Gammaplex; GAMUNEX-C; Hizentra; Human immunoglobulin G; HUMAN NORMAL IMMUNOGLOBULIN; HYQVIA; Immune globulin; Immunoglobulin; IMMUNOGLOBULIN G; IVIg; KIOVIG; OCTAGAM; PANZYGA; Privigen; Vivaglobin---10件: 11, 13, 14, 17, 43, 45, 50, 51, 63, 65
22 Hydrogen 2件: Dihydrogen; Hydrogen---7件: 5, 6, 17, 65, 83, 97, 226
23 Inosine 1件: Inosine1件: D00054 --6件: 2, 6, 13, 17, 85, 122
24 Levodopa 9件: Carbidopa-Levodopa; DUODOPA; Inbrija; L-DOPA; Levodopa; PARCOPA; SINEMET; SINEMET CR; Stalevo1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬6件: 6, 17, 90, 140, 164, 201
25 Lithium carbonate 2件: Lithium; Lithium Carbonate1件: D00801 --5件: 2, 13, 17, 18, 127
26 Losartan 3件: Cozaar; Losartan; LOSARTAN POTASSIUM1件: D08146 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
27 Metoprolol 2件: Metoprolol; Metoprolol succinate1件: D02358 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬6件: 17, 57, 58, 113, 193, 226
28 Midodrine 2件: Midodrine; MIDODRINE HYDROCHLORIDE1件: D08220 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬3件: 6, 17, 58
29 Nebivolol 1件: Nebivolol1件: D05127 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 17, 85, 113, 167
30 Nitrogen 1件: Nitrogen1件: D00083 --5件: 5, 6, 17, 211, 299
31 Pseudoephedrine 1件: Pseudoephedrine1件: D08449 9件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		14件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 17
32 Raclopride 1件: Raclopride---4件: 5, 6, 7, 17
33 Rasagiline 4件: Azilect; Rasagilina; Rasagiline; Rasagiline mesylate2件: D08469 ,
D10829 		1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬6件: 2, 5, 6, 17, 58, 66
34 Rifampicin 2件: Rifampicin; Rifampin1件: D00211 --9件: 6, 13, 17, 46, 84, 86, 93, 299, 338
35 Riluzole 2件: Rilutek; Riluzole1件: D00775 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		23件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬9件: 2, 3, 5, 8, 13, 17, 18, 203, 206
36 Safinamide 3件: Safinamida; SAFINAMIDE; Xadago1件: D10158 1件: MAOB 💬14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬2件: 6, 17
37 Sirolimus 3件: RAPAMUNE; Rapamycin; SIROLIMUS1件: D00753 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬40件: 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331
38 Tea leaf 1件: Tea leaf---2件: 17, 46
39 Tolterodine 1件: Tolterodine1件: D00646 1件: CHRM3 💬11件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬2件: 17, 53
40 Trimethaphan 1件: Trimethaphan---1件: 17
41 Ubiquinol 1件: Ubiquinol---3件: 6, 8, 17
42 Verdiperstat 1件: Verdiperstat1件: D11684 1件: MPO 💬5件: Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬3件: 2, 17, 127
43 Water 8件: AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: D00001 --21件: 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299
44 Zoledronic acid 4件: Aclasta; Zoledronate; Zoledronic acid; Zometa2件: D01968 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬13件: 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333