Carbamazepine ( DrugBank: Carbamazepine )

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3 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
6	パーキンソン病	1
13	多発性硬化症／視神経脊髄炎	1
231	α1−アンチトリプシン欠乏症	1

6. パーキンソン病

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臨床試験数 : 2,307 /  薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05581823 (ClinicalTrials.gov)	October 19, 2022	12/10/2022	Study to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Inducer Carbamazepine on Tavapadon Pharmacokinetics in Healthy Adult Participants	A Phase 1, Open-label, Fixed-sequence, Crossover Trial to Evaluate the Effects of Cytochrome P450 (CYP) 3A4 Induction by Carbamazepine on the Steady-state Pharmacokinetics of Tavapadon in Healthy Adult Participants	Parkinson Disease	Drug: Tavapadon;Drug: Carbamazepine	Cerevel Therapeutics, LLC	NULL	Active, not recruiting	18 Years	55 Years	All	16	Phase 1	United States

13. 多発性硬化症／視神経脊髄炎

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臨床試験数 : 3,340 /  薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04371575 (ClinicalTrials.gov)	September 1, 2012	29/4/2020	Symptomatic Trigeminal Neuralgia Attributed to Multiple Sclerosis - a Prospective Study in 60 Patients	Symptomatic Trigeminal Neuralgia Attributed to Multiple Sclerosis - Clinical Characteristics, Neuroanatomical Abnormalities and Treatment Efficacy	Trigeminal Neuralgia;Multiple Sclerosis;Pain, Neuropathic	Drug: Carbamazepine	Stine Maarbjerg, MD PhD	NULL	Completed	N/A	N/A	All	60		NULL

231. α1−アンチトリプシン欠乏症

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臨床試験数 : 93 /  薬物数 : 77 - (DrugBank : 8) / 標的遺伝子数 : 10 - 標的パスウェイ数 : 36

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01379469 (ClinicalTrials.gov)	January 2012	15/6/2011	Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency	A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency	Alpha-1-antitrypsin Deficiency;Liver Cirrhosis	Drug: Drug-Carbamazepine (Tegretol XR);Drug: Carbamazepine (Tegretol XR) Placebo	Washington University School of Medicine	Novartis;National Institutes of Health (NIH);National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);University of Pittsburgh	Terminated	14 Years	80 Years	All	20	Phase 2	United States