Dobutamine ( DrugBank: Dobutamine )


4 diseases
IDDisease name (Link within this page)Number of trials
57Idiopathic dilated cardiomyopathy1
58Hypertrophic cardiomyopathy2
86Pulmonary arterial hypertension1
215Tetralogy of Fallot1

57. Idiopathic dilated cardiomyopathy


Clinical trials : 11 Drugs : 23 - (DrugBank : 12) / Drug target genes : 9 - Drug target pathways : 35
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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PhaseCountries
1NCT00281255
(ClinicalTrials.gov)
June 200320/1/2006Intravenous Allopurinol to Improve Heart Function in Individuals With Dilated CardiomyopathyAllopurinol and Cardiac Function Pilot Study in Idiopathic Dilated CardiomyopathyCardiovascular Diseases;Cardiomyopathy, Dilated;Heart Diseases;Heart Failure, CongestiveDrug: Allopurinol;Drug: DobutamineUniversity of PennsylvaniaNational Heart, Lung, and Blood Institute (NHLBI)Withdrawn18 YearsN/ABoth0Phase 1/Phase 2United States

58. Hypertrophic cardiomyopathy


Clinical trials : 126 Drugs : 135 - (DrugBank : 42) / Drug target genes : 46 - Drug target pathways : 162
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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PhaseCountries
1NCT05025644
(ClinicalTrials.gov)
March 202311/8/2021Quantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress TestQuantitative Assessment of Hypertrophic Obstructive Cardiomyopathy With Intraoperative Three-dimensional Transesophageal Echocardiography Under Provocative Dobutamine Stress TestHypertrophic Obstructive CardiomyopathyDrug: Pre and post-CPB Drug: Dobutamine Hydrochloride;Drug: Post-CPB Drug: Dobutamine HydrochlorideUniversity Health Network, TorontoNULLNot yet recruiting18 YearsN/AAll60Phase 4NULL
2NCT01375335
(ClinicalTrials.gov)
June 201114/6/2011The Effects of Dobutamine on Postoperative Cardiac Function in Aortic Valve ReplacementThe Effects of Dobutamine on Postoperative Systolic Deformation and Diastolic Function in Patients With Hypertrophic Cardiomyopathy Operated for Aortic Valve StenosisHeart FailureDrug: DobutamineUniversity of AarhusNULLSuspended19 Years90 YearsBoth10Phase 4Denmark

86. Pulmonary arterial hypertension


Clinical trials : 1,205 Drugs : 684 - (DrugBank : 124) / Drug target genes : 100 - Drug target pathways : 193
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
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agemin
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agemax
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gender
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PhaseCountries
1NCT05587400
(ClinicalTrials.gov)
July 27, 202223/9/2022Consistency of Electrical Cardiometry and Pulmonary Artery CatheterThe Consistency of Cardiac Output Measured by Electrical Cardiometry and Pulmonary Artery Catheter in Cardiac Surgery Patients With Pulmonary Arterial Hypertension or Right Heart DysfunctionPulmonary Arterial Hypertension;Right Ventricular DysfunctionBehavioral: passive leg raising;Drug: dobutamine test;Drug: inhaled nitric oxideShanghai Zhongshan HospitalNULLRecruiting18 Years80 YearsAll199N/AChina

215. Tetralogy of Fallot


Clinical trials : 18 Drugs : 26 - (DrugBank : 14) / Drug target genes : 13 - Drug target pathways : 45
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
1EUCTR2007-003461-41-DE
(EUCTR)
13/11/200710/09/2007Cardiac imaging under dobutamine stress for early assessment of right ventricular function in patients with tetralogy of Fallot and pulmonary regurgitation - Fallot-stressCardiac imaging under dobutamine stress for early assessment of right ventricular function in patients with tetralogy of Fallot and pulmonary regurgitation - Fallot-stress Fallot tetralogy late after repair with marked pulmonary valve incompetenceINN or Proposed INN: DobutamineDeutsche Herzzentrum Berlin, Kompetenznetz Angeborene HerzfehlerNULLNot RecruitingFemale: yes
Male: yes
80Germany