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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
118 FDG----1件: 145
2Acetate1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
3ACTH1件: Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 13, 66, 145, 193, 222
4Adrenocorticotropin hormone----1件: 145
5AMZ002----1件: 145
6Cannabidiol1件: Cannabidiol1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬18件: 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
7Cannabidiol (CBD)1件: Cannabidiol1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬7件: 6, 13, 140, 144, 145, 156, 158
8Cannabidiol Oral Solution1件: Cannabidiol1件: D10915 2件: CNR1,
CNR2 💬		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬4件: 140, 144, 145, 193
9CBD----12件: 2, 6, 8, 13, 36, 46, 140, 144, 145, 156, 158, 206
10Combination therapy with vigabatrin and prednisolone2件: Prednisolone,
Vigabatrin		9件: D00472 ,
D00535 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		2件: ABAT,
NR3C1 💬		8件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Neuroactive ligand-receptor interaction, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬1件: 145
11Cosyntropin1件: Tetracosactide1件: D00284 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 83, 113, 145
12Cosyntropin Injectable Suspension 1 MG/ML + vigabatrin2件: Tetracosactide,
Vigabatrin		2件: D00284 ,
D00535 		2件: ABAT,
MC2R 💬		12件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, Metabolic pathways, Neuroactive ligand-receptor interaction, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, cAMP signaling pathway 💬1件: 145
13Cosyntropin Injectable Suspension, 1 mg/mL1件: Tetracosactide1件: D00284 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 145
14Decortin H----3件: 66, 97, 145
15FENFLURAMINE1件: Fenfluramine1件: D07945 4件: HTR2A,
HTR2B,
HTR2C,
SLC6A4 💬		6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬4件: 140, 144, 145, 149
16Ganaxolone1件: Ganaxolone1件: D04300 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬4件: 145, 152, 158, 206
17GWP42003-P----5件: 140, 144, 145, 156, 158
18Intravenous Methylprednisolone1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 13, 145
19JBPOS01011件: JBPOS0101---1件: 145
20Ketogenic diet----2件: 145, 230
21M071754----1件: 145
22Melatonin1件: Melatonin1件: D08170 2件: MTNR1A,
MTNR1B 💬		2件: Circadian entrainment, Neuroactive ligand-receptor interaction 💬12件: 6, 8, 13, 37, 46, 49, 90, 97, 144, 145, 149, 202
23Methylprednisolone1件: Methylprednisolone6件: D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
24Modified Atkins diet----3件: 145, 157, 187
25Null----16件: 6, 13, 15, 28, 37, 46, 49, 51, 63, 86, 90, 96, 97, 107, 145, 271
26Oral Pednisolone----1件: 145
27Oral prednisolone1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 49, 96, 145
28Other: modified Atkins diet----1件: 145
29PREDNISOLONE1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬43件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300, 307
30PYRIDOXINE1件: Pyridoxine2件: D02179 ,
D08454 		--3件: 93, 145, 320
31Pyridoxine plus prednisolone2件: Prednisolone,
Pyridoxine		10件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D02179 ,
D03301 ,
D08454 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 145
32Radiprodil1件: Radiprodil---1件: 145
33SABRIL1件: Vigabatrin1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬2件: 145, 158
34Sabril granules for oral use1件: Vigabatrin1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬1件: 145
35SABRIL SACHETS1件: Vigabatrin1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬1件: 145
36Sabrilex----1件: 145
37Sabril®1件: Vigabatrin1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬1件: 145
38SOLUBLE PREDNISOLONE TABLETS1件: Prednisolone8件: D00472 ,
D00980 ,
D00981 ,
D00982 ,
D01239 ,
D01998 ,
D02156 ,
D03301 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 145
39SPT3162----1件: 145
40Synacthen Depot1件: Tetracosactide1件: D00284 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 83, 145, 222
41Tetracosactide1件: Tetracosactide1件: D00284 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 83, 113, 145, 222
42Tetracosactide acetate2件: Acetate,
Tetracosactide		1件: D00284 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 83, 145
43Tricaprilin1件: Tricaprylin---1件: 145
44UCB3491----1件: 145
45VGB-ST----1件: 145
46VGB-ST soluble tablets----1件: 145
47VIGABATRIN1件: Vigabatrin1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬2件: 145, 158
48Vigabatrin Tablets1件: Vigabatrin1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬1件: 145
49Vigabatrin: Vigabatrin new ST formulation then Sabril®1件: Vigabatrin1件: D00535 1件: ABAT 💬7件: Alanine, aspartate and glutamate metabolism, Butanoate metabolism, GABAergic synapse, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬1件: 145
50Vitamin B11件: Thiamine1件: D08580 --1件: 145