Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Busulfan, Cyclophosphamide, Antithymocyte Globulin
(Synonym: D00287)		2件: Busulfan,
Cyclophosphamide		3件: D00248 ,
D00287 ,
D07760 		--2件: 19, 20
2Busulfan, Cyclophosphamide, ATG
(Synonym: D00287)		2件: Busulfan,
Cyclophosphamide		3件: D00248 ,
D00287 ,
D07760 		--1件: 19
3Busulfan, Cyclophosphamide, ATG, GCSF
(Synonym: D00287)		2件: Busulfan,
Cyclophosphamide		3件: D00248 ,
D00287 ,
D07760 		--2件: 65, 284
4Busulfan, Cyclophosphamide, Thymoglobulin, Fludarabine (Conditioning regimen)
(Synonym: D00287)		4件: Antithymocyte immunoglobulin (rabbit),
Busulfan,
Cyclophosphamide,
Fludarabine		5件: D00248 ,
D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬1件: 326
5Busulfan, fludarabine, & cyclophosphamide with immunosuppression with ATG and cyclosporine.
(Synonym: D00287)		4件: Busulfan,
Cyclophosphamide,
Cyclosporine,
Fludarabine		6件: D00184 ,
D00248 ,
D00287 ,
D01907 ,
D07760 ,
D07966 		6件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2,
RRM1 💬		38件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Drug metabolism - other enzymes, Glucagon signaling pathway, Glutamatergic synapse, Glutathione metabolism, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Metabolic pathways, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Purine metabolism, Pyrimidine metabolism, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬2件: 60, 285
6Campath, Fludarabine, Cyclophosphamide
(Synonym: D00287)		2件: Cyclophosphamide,
Fludarabine		4件: D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬2件: 65, 284
7Cyclophosphamide
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--45件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
8Cyclophosphamide (CY)
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 60
9Cyclophosphamide (CY) (Plan 1)
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--2件: 60, 285
10Cyclophosphamide (CY) (Plan 2)
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--2件: 60, 285
11Cyclophosphamide (Cytoxan)
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 65
12Cyclophosphamide (drug)
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 13
13Cyclophosphamide + pred
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 283
14Cyclophosphamide 100mg
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 60
15Cyclophosphamide 150mg
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 60
16Cyclophosphamide 30
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--3件: 65, 285, 326
17Cyclophosphamide 40
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--3件: 65, 285, 326
18Cyclophosphamide 50mg
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 60
19Cyclophosphamide 50Mg Oral Tablet
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 162
20Cyclophosphamide and ATG
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 13
21Cyclophosphamide and fludarabine
(Synonym: D00287)		2件: Cyclophosphamide,
Fludarabine		4件: D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬1件: 13
22Cyclophosphamide and steroids
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 222
23Cyclophosphamide Dose Level 1
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--2件: 65, 284
24Cyclophosphamide Dose Level 2
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--2件: 65, 284
25Cyclophosphamide Dose Level 3
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--2件: 65, 284
26Cyclophosphamide Dose Level 4
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--2件: 65, 284
27Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids
(Synonym: D00287)		3件: Azathioprine,
Cyclophosphamide,
Methotrexate		6件: D00142 ,
D00238 ,
D00287 ,
D02115 ,
D03033 ,
D07760 		2件: DHFR,
DHFR2 💬		5件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬1件: 44
28Cyclophosphamide Injection 1g
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--3件: 50, 51, 52
29CYCLOPHOSPHAMIDE MONOHYDRATE
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--4件: 13, 60, 96, 256
30Cyclophosphamide post transplant
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 65
31Cyclophosphamide(CTX)
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 224
32Cyclophosphamide, Azathioprine,prednisone,methylprednisolone
(Synonym: D00287)		4件: Azathioprine,
Cyclophosphamide,
Methylprednisolone,
Prednisone		11件: D00238 ,
D00287 ,
D00407 ,
D00473 ,
D00751 ,
D00979 ,
D03033 ,
D05000 ,
D05001 ,
D05002 ,
D07760 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 42, 43, 45
33Cyclophosphamide, bortezomib, and Dexamethasone (CyBorD)
(Synonym: D00287)		3件: Bortezomib,
Cyclophosphamide,
Dexamethasone		12件: D00287 ,
D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 ,
D03150 ,
D07760 		2件: NR3C1,
PSMB5 💬		9件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Neuroactive ligand-receptor interaction, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬1件: 28
34Cyclophosphamide, bortezomib, and Dexamethasone (CyBorD) regimen
(Synonym: D00287)		3件: Bortezomib,
Cyclophosphamide,
Dexamethasone		12件: D00287 ,
D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 ,
D03150 ,
D07760 		2件: NR3C1,
PSMB5 💬		9件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Neuroactive ligand-receptor interaction, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬1件: 28
35Cyclophosphamide, Bortezomib, dexamethasone
(Synonym: D00287)		3件: Bortezomib,
Cyclophosphamide,
Dexamethasone		12件: D00287 ,
D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 ,
D03150 ,
D07760 		2件: NR3C1,
PSMB5 💬		9件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Neuroactive ligand-receptor interaction, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬1件: 28
36Cyclophosphamide, Bortezomib, dexamethasone plus Daratumumab
(Synonym: D00287)		4件: Bortezomib,
Cyclophosphamide,
Daratumumab,
Dexamethasone		13件: D00287 ,
D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 ,
D03150 ,
D07760 ,
D10777 		3件: CD38,
NR3C1,
PSMB5 💬		16件: Alzheimer disease, Amyotrophic lateral sclerosis, Calcium signaling pathway, Hematopoietic cell lineage, Huntington disease, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Salivary secretion, Spinocerebellar ataxia 💬1件: 28
37Cyclophosphamide, Fludarabine
(Synonym: D00287)		2件: Cyclophosphamide,
Fludarabine		4件: D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬1件: 285
38Cyclophosphamide, fludarabine , thymoglobulin
(Synonym: D00287)		3件: Antithymocyte immunoglobulin (rabbit),
Cyclophosphamide,
Fludarabine		4件: D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬1件: 60
39Cyclophosphamide, Fludarabine, Rabbit ATG
(Synonym: D00287)		4件: Antithymocyte immunoglobulin (rabbit),
Cyclophosphamide,
Fludarabine,
Rabbit		4件: D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬1件: 60
40Cyclophosphamide, Fludarabine, Thymoglobulin
(Synonym: D00287)		3件: Antithymocyte immunoglobulin (rabbit),
Cyclophosphamide,
Fludarabine		4件: D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬1件: 60
41Cyclophosphamide,Campath IH and TBI
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 60
42Cyclophosphamide,cyclosporine A
(Synonym: D00287)		2件: Cyclophosphamide,
Cyclosporine		3件: D00184 ,
D00287 ,
D07760 		5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬1件: 60
43Cyclophosphamide-prednisone-azathioprine
(Synonym: D00287)		3件: Azathioprine,
Cyclophosphamide,
Prednisone		5件: D00238 ,
D00287 ,
D00473 ,
D03033 ,
D07760 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 49
44Cyclophosphamide/azathioprine
(Synonym: D00287)		2件: Azathioprine,
Cyclophosphamide		4件: D00238 ,
D00287 ,
D03033 ,
D07760 		--1件: 44
45Cyclophosphamide/Glatiramer acetate
(Synonym: D00287)		3件: Acetate,
Cyclophosphamide,
Glatiramer		3件: D00287 ,
D04318 ,
D07760 		20件: HLA-A,
HLA-B,
HLA-C,
HLA-DMA,
HLA-DMB,
HLA-DOA,
HLA-DOB,
HLA-DPA1,
HLA-DPB1,
HLA-DQA1,
HLA-DQA2,
HLA-DQB1,
HLA-DRA,
HLA-DRB1,
HLA-DRB3,
HLA-DRB4,
HLA-DRB5,
HLA-E,
HLA-F,
HLA-G 💬		32件: Allograft rejection, Antigen processing and presentation, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cellular senescence, Endocytosis, Epstein-Barr virus infection, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Inflammatory bowel disease, Influenza A, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Phagosome, Rheumatoid arthritis, Staphylococcus aureus infection, Systemic lupus erythematosus, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Viral carcinogenesis, Viral myocarditis 💬1件: 13
46Doxorubicin, methotrexate, cyclophosphamide, L-asparaginase
(Synonym: D00287)		4件: Asparaginase Escherichia coli,
Cyclophosphamide,
Doxorubicin,
Methotrexate		6件: D00142 ,
D00287 ,
D02115 ,
D02997 ,
D03899 ,
D07760 		4件: DHFR,
DHFR2,
TOP2A,
TOP2B 💬		6件: Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate, Platinum drug resistance 💬1件: 65
47Fludarabine, Cyclophosphamide
(Synonym: D00287)		2件: Cyclophosphamide,
Fludarabine		4件: D00287 ,
D01907 ,
D07760 ,
D07966 		1件: RRM1 💬5件: Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬1件: 60
48Haploidentical HSCT using TBI free regimen, ''ATG'' with ''Post transplant cyclophosphamide''
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 60
49High-dose Cyclophosphamide
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 96
50IV Cyclophosphamide
(Synonym: D00287)		1件: Cyclophosphamide2件: D00287 ,
D07760 		--1件: 51
51Lenalidomide, Dexamethasone and Cyclophosphamide
(Synonym: D00287)		3件: Cyclophosphamide,
Dexamethasone,
Lenalidomide		12件: D00287 ,
D00292 ,
D00975 ,
D01510 ,
D01615 ,
D01632 ,
D01948 ,
D02174 ,
D02591 ,
D02592 ,
D04687 ,
D07760 		2件: NR3C1,
TNF 💬		68件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 28
52Prednisone and cyclophosphamide
(Synonym: D00287)		2件: Cyclophosphamide,
Prednisone		3件: D00287 ,
D00473 ,
D07760 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
53Prednisone plus cyclophosphamide
(Synonym: D00287)		2件: Cyclophosphamide,
Prednisone		3件: D00287 ,
D00473 ,
D07760 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 66
54Prednisone, cyclophosphamide
(Synonym: D00287)		2件: Cyclophosphamide,
Prednisone		3件: D00287 ,
D00473 ,
D07760 		1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 40
55Rituximab and Cyclophosphamide IV
(Synonym: D00287)		2件: Cyclophosphamide,
Rituximab		3件: D00287 ,
D02994 ,
D07760 		1件: MS4A1 💬1件: Hematopoietic cell lineage 💬1件: 35
56Thalidomide, cyclophosphamide and prednisone
(Synonym: D00287)		3件: Cyclophosphamide,
Prednisone,
Thalidomide		4件: D00287 ,
D00473 ,
D00754 ,
D07760 		2件: NR3C1,
TNF 💬		68件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Neuroactive ligand-receptor interaction, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 331