Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetate 1件: Acetate---43件: 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299
2 Acipimox 1件: Acipimox1件: D07190 --2件: 78, 265
3 Albumin human 5件: Albumin; Human albumin; Human serum albumin; Optison; Serum albumin2件: D02792 ,
D05424 		--3件: 2, 78, 96
4 Amitriptyline 3件: Amitriptylin; Amitriptyline; Amitriptyline hydrochloride2件: D00809 ,
D07448 		2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
5 Anastrozole 2件: ANASTROZOLE; Arimidex1件: D00960 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
6 Arginine 6件: Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene1件: D02982 --12件: 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299
7 ARX201 1件: ARX201---1件: 78
8 Caffeine 1件: Caffeine2件: D00528 ,
D01453 		11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
9 Chloride ion 1件: Chloride---29件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 271, 288, 296, 297, 299, 338
10 Clonidine 4件: Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE2件: D00281 ,
D00604 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
11 Corticotropin 5件: ACTH; ACTHAR; Adrenocorticotropic hormone; Corticotrophin; Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬15件: 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
12 Dextromethorphan 4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta3件: D00848 ,
D03742 ,
D03744 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
13 Diclofenac 3件: Diclofenac; Diclofenac Sodium; Diclofenac SR3件: D00903 ,
D00904 ,
D07816 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
14 Donepezil 3件: Aricept; Donepezil; Donepezil hydrochloride2件: D00670 ,
D07869 		1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
15 Escherichia coli 1件: Escherichia coli---2件: 53, 78
16 Exenatide 3件: BYDUREON; Byetta; EXENATIDE1件: D04121 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233
17 Fluoxetine 5件: Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC2件: D00326 ,
D00823 		1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
18 Gelatin 3件: Gelatin; Gelatine; Sulfur Colloid2件: D00115 ,
D06892 		--7件: 19, 28, 62, 78, 97, 269, 299
19 Glucagon 1件: Glucagon2件: D00116 ,
D02118 		1件: GCGR 💬2件: Glucagon signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 78
20 Hydrocortisone 6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum1件: D00088 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
21 Lenomorelin 1件: Ghrelin---6件: 6, 78, 193, 201, 202, 299
22 Levothyroxine 3件: Levothyroxine; Thyroid; Thyroxine2件: D01010 ,
D08125 		2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬5件: 19, 49, 78, 80, 222
23 Liothyronine 4件: Liothyronine; Liothyronine sodium; Thyroid; Triiodothyronine2件: D01011 ,
D08128 		2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬4件: 13, 78, 210, 212
24 Lonapegsomatropin 1件: LONAPEGSOMATROPIN1件: D11486 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
25 Macimorelin 2件: Macimorelin; Macrilen1件: D10563 1件: GHSR 💬3件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 78
26 Manganese citrate 1件: Release---12件: 6, 8, 13, 46, 65, 78, 81, 96, 97, 206, 226, 299
27 Mecasermin 3件: Increlex; Mecasermin; MECASERMINA2件: D03297 ,
D04870 		2件: GHR,
IGF1R 💬		33件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬6件: 65, 78, 96, 168, 265, 299
28 Methyl salicylate 2-ethylbutyrate 1件: TheraDerm---1件: 78
29 Niacin 2件: Niacin; Nicotinic acid1件: D00049 --4件: 6, 78, 79, 265
30 Pegvisomant 1件: Pegvisomant1件: D05394 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
31 Phosphate ion 1件: Phosphate---33件: 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
32 Pioglitazone 1件: Pioglitazone2件: D00945 ,
D08378 		1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
33 Polyethylene glycol 4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 33501件: D03370 --14件: 6, 13, 41, 46, 65, 78, 96, 97, 140, 144, 235, 240, 276, 299
34 Sodium chloride 6件: Lactated Ringers; Natriumchlorid; REBIF; SALINE; Sodium chloride; SPORANOX1件: D02056 --21件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
35 Somapacitan 1件: SOMAPACITAN1件: D11194 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
36 Somatorelin 2件: GHRH; Somatorelin1件: D08523 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 13, 78
37 Somatostatin 1件: Somatostatin1件: D07431 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬		4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 78
38 Somatotropin 17件: Genotropin; GROWTH HORMONE; Human Growth Hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; RECOMBINANT HUMAN GROWTH HORMONE; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton1件: D02691 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
39 Somatrogon 1件: Somatrogon1件: D10990 --1件: 78
40 Somatropin pegol 1件: NNC126-0083---1件: 78
41 Somavaratan 1件: Somavaratan1件: D11193 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
42 Strontium ranelate 1件: Strontium ranelate1件: D08468 --1件: 78
43 Tesamorelin 2件: GHRH; Tesamorelin1件: D06655 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 78, 265
44 Testosterone 1件: Testosterone6件: D00075 ,
D00957 ,
D00958 ,
D00959 ,
D06085 ,
D06087 		1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
45 Tetracosactide 4件: Cosyntropin; Synacthen Depot; Tetracosactide; Tetracosactrin1件: D00284 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 78, 83, 113, 145, 222
46 Thyroid, porcine 1件: Thyroid---1件: 78
47 Tiratricol 1件: Tiratricol1件: D07214 2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬2件: 78, 139
48 Tramadol 2件: Tramadol; Ultracet2件: D01355 ,
D08623 		1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
49 Water 9件: AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine Green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION1件: D00001 --23件: 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299