Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Nitric oxide 1件: Nitric Oxide3件: INOmax; Nitric Oxide; Nitrosyl; --16件: 6, 13, 46, 58, 85, 86, 96, 97, 98, 210, 222, 226, 251, 294, 299, 321
2 Hydrocortisone 1件: Hydrocortisone6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
3 Cholecalciferol 1件: Cholecalciferol5件: Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3; 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬25件: 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 75, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
4 Budesonide 1件: Budesonide4件: BUDESONIDE; Entocort; Jorveza; Symbicort; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬9件: 66, 93, 94, 95, 96, 97, 98, 228, 299
5 Famotidine 1件: Famotidine2件: FAMOTIDINA; Famotidine; 1件: HRH2 💬3件: Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬7件: 6, 46, 61, 86, 98, 107, 300
6 Lansoprazole 1件: Lansoprazole1件: Lansoprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬7件: 63, 71, 85, 98, 166, 222, 299
7 Losartan potassium 1件: Losartan3件: Cozaar; Losartan; LOSARTAN POTASSIUM; 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
8 Loratadine 1件: Loratadine2件: Loratadina; Loratadine; 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬4件: 13, 46, 89, 98
9 Sucralfate 1件: Sucralfate1件: Sucralfate; --1件: 98
10 Omeprazole 1件: Omeprazole5件: Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
11 Cromolyn sodium 1件: Cromoglicic acid4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium; --3件: 2, 85, 98
12 Montelukast sodium 1件: Montelukast3件: Montelukast; MONTELUKAST SODIUM; Singulair; 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
13 Sevoflurane 1件: Sevoflurane1件: Sevoflurane; --7件: 6, 21, 22, 34, 98, 225, 296
14 Propofol 1件: Propofol2件: Propofol; Propofol Injection; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬10件: 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
15 Beclomethasone dipropionate 1件: Beclomethasone dipropionate2件: BECLOMETASONE DIPROPIONATE; Beclomethasone dipropionate; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 85, 97, 98
16 Mometasone furoate 2件: Mometasone,
Mometasone furoate		3件: Mometasone; MOMETASONE FUROATE; Nasonex; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬4件: 98, 98, 162, 162
17 Sirolimus 1件: Sirolimus3件: RAPAMUNE; Rapamycin; Sirolimus; 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
18 Citalopram hydrobromide 1件: Citalopram1件: Citalopram; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
19 Bethanechol chloride 1件: Bethanechol1件: Bethanechol; 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬1件: 98
20 Diphenylpyraline hydrochloride 1件: Diphenylpyraline0件: 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 98
21 Omeprazole sodium 1件: Omeprazole5件: Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
22 Diphenylpyraline teoclate 1件: Diphenylpyraline0件: 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 98
23 Fluticasone propionate 1件: Fluticasone propionate3件: Flovent; Fluticasone; FLUTICASONE PROPIONATE; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 228
24 Esomeprazole magnesium 1件: Esomeprazole3件: Esomeprazole; Nexium; Omeprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
25 Infliximab 1件: Infliximab6件: Flixabi; INFLECTRA; Infliximab; Remicade; Remsima; Zessly; 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
26 Arginine 1件: Arginine6件: Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene; --12件: 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299
27 Mometasone furoate hydrate 1件: Mometasone1件: Mometasone; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162
28 Esomeprazole sodium 1件: Esomeprazole3件: Esomeprazole; Nexium; Omeprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
29 Mepolizumab 1件: Mepolizumab2件: Mepolizumab; NUCALA; 1件: IL5 💬13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬4件: 44, 45, 98, 162
30 Omalizumab 1件: Omalizumab2件: Omalizumab; XOLAIR; 1件: FCER1A 💬4件: Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬7件: 46, 53, 65, 98, 162, 226, 299
31 Omeprazole magnesium 1件: Omeprazole5件: Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
32 Omeprazole sodium injection 1件: Omeprazole5件: Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬16件: 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
33 Xanthan gum 1件: Xanthan gum1件: Xanthan gum; --1件: 98
34 Xylose 1件: Xylose1件: Xylose; --1件: 98
35 Honey 1件: Honey1件: Honey; --3件: 57, 98, 299
36 Wheat 1件: Wheat1件: Wheat; --3件: 6, 98, 266
37 Beclometasone 1件: Beclomethasone dipropionate2件: Beclometasone dipropionate; Beclomethasone dipropionate; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 85, 97, 98
38 Citalopram 1件: Citalopram1件: Citalopram; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬7件: 6, 8, 13, 18, 46, 98, 127
39 Cromoglicic acid 1件: Cromoglicic acid4件: Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium; --3件: 2, 85, 98
40 Diphenylpyraline 1件: Diphenylpyraline0件: 1件: HRH1 💬3件: Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬1件: 98
41 Esomeprazole 1件: Esomeprazole3件: Esomeprazole; Nexium; Omeprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
42 Fluticasone 1件: Fluticasone1件: Fluticasone; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬3件: 98, 228, 299
43 Losartan 1件: Losartan3件: Cozaar; Losartan; LOSARTAN POTASSIUM; 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299
44 Mometasone 1件: Mometasone1件: Mometasone; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬2件: 98, 162
45 Montelukast 1件: Montelukast3件: Montelukast; MONTELUKAST SODIUM; Singulair; 1件: CYSLTR1 💬2件: Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬8件: 6, 13, 46, 61, 63, 85, 98, 228
46 Potassium 1件: Potassium1件: Potassium; --12件: 36, 46, 66, 67, 88, 94, 98, 115, 167, 179, 215, 235
47 Dexlansoprazole 1件: Dexlansoprazole1件: Dexlansoprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬1件: 98
48 Reslizumab 1件: Reslizumab1件: Reslizumab; 1件: IL5 💬13件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, IL-17 signaling pathway, Inflammatory bowel disease, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Th1 and Th2 cell differentiation 💬2件: 44, 98
49 Esomeprazole potassium 1件: Esomeprazole3件: Esomeprazole; Nexium; Omeprazole; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬8件: 13, 46, 86, 98, 107, 113, 298, 299
50 Benralizumab 1件: Benralizumab2件: Benralizumab; Fasenra; 1件: IL5RA 💬4件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer 💬5件: 44, 45, 98, 162, 299
51 Dupilumab 1件: Dupilumab2件: DUPILUMAB; Dupixent; 1件: IL4R 💬8件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬4件: 51, 98, 160, 162
52 Etrasimod 1件: Etrasimod1件: Etrasimod; 5件: S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬		3件: FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 96, 97, 98
53 Vonoprazan 1件: Vonoprazan1件: Vonoprazan; 2件: ATP4A,
ATP4B 💬		4件: Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬2件: 63, 98
54 Lirentelimab 1件: Lirentelimab1件: Lirentelimab; 1件: SIGLEC8 💬-1件: 98