Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CCN2 1件: Hippo signaling pathway D10969 Pamrevlumab 2件: 85, 113
2 SMAD7 2件: TGF-beta signaling pathway, Hippo signaling pathway D10956 Mongersen 2件: 96, 97
3 BMPR2 4件: TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, MicroRNAs in cancer D03779 Dibotermin alfa 1件: 34
4 TGFB1 20件: MAPK signaling pathway, TGF-beta signaling pathway, Osteoclast differentiation, Hippo signaling pathway, Th17 cell differentiation, Intestinal immune network for IgA production, Relaxin signaling pathway, Non-alcoholic fatty liver disease, Leishmaniasis, Malaria, Toxoplasmosis, Tuberculosis, Human T-cell leukemia virus 1 infection, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Inflammatory bowel disease, Rheumatoid arthritis, Hypertrophic cardiomyopathy D09620 Fresolimumab 4件: 51, 85, 222, 274
5 TGFB2 17件: MAPK signaling pathway, TGF-beta signaling pathway, Osteoclast differentiation, Hippo signaling pathway, Leishmaniasis, Malaria, Toxoplasmosis, Tuberculosis, Human T-cell leukemia virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Renal cell carcinoma, Pancreatic cancer, Inflammatory bowel disease, Rheumatoid arthritis, Hypertrophic cardiomyopathy D09620 Fresolimumab 4件: 51, 85, 222, 274
6 TGFB3 14件: MAPK signaling pathway, TGF-beta signaling pathway, Hippo signaling pathway, Leishmaniasis, Malaria, Toxoplasmosis, Tuberculosis, Human T-cell leukemia virus 1 infection, Pathways in cancer, Renal cell carcinoma, Pancreatic cancer, Inflammatory bowel disease, Rheumatoid arthritis, Hypertrophic cardiomyopathy D09620 Fresolimumab 4件: 51, 85, 222, 274