Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 TNFSF13B 3件: NF-kappa B signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis D03068 Belimumab 12件: 11, 13, 43, 44, 46, 49, 51, 53, 66, 222, 296, 300
2 TNFSF13B 3件: NF-kappa B signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis D09704 Atacicept 4件: 13, 46, 49, 66
3 TNFSF13B 3件: NF-kappa B signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis D10083 Tabalumab 2件: 46, 49
4 TNFSF13B 3件: NF-kappa B signaling pathway, Intestinal immune network for IgA production, Rheumatoid arthritis D11127 Tibulizumab 1件: 53
5 TNFRSF13C 3件: NF-kappa B signaling pathway, Intestinal immune network for IgA production, Primary immunodeficiency D12151 Ianalumab 5件: 35, 46, 49, 53, 95
6 HLA-DMA 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
7 HLA-DMB 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
8 HLA-DOA 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
9 HLA-DOB 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
10 HLA-DPA1 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
11 HLA-DPB1 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
12 HLA-DQA1 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
13 HLA-DQA2 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
14 HLA-DQB1 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
15 HLA-DRA 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
16 HLA-DRB1 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
17 HLA-DRB3 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
18 HLA-DRB4 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
19 HLA-DRB5 12件: Phagosome, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
20 IL4 8件: PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Intestinal immune network for IgA production, Leishmaniasis, Pathways in cancer D03117 Binetrakin 1件: 46
21 IL5 5件: JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, T cell receptor signaling pathway, Intestinal immune network for IgA production, Pathways in cancer D04923 Mepolizumab 4件: 44, 45, 98, 162
22 IL5 5件: JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, T cell receptor signaling pathway, Intestinal immune network for IgA production, Pathways in cancer D08985 Reslizumab 2件: 44, 98
23 IL6 24件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, TNF signaling pathway, Intestinal immune network for IgA production, Non-alcoholic fatty liver disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Malaria, Tuberculosis, Measles, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis, Lipid and atherosclerosis D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
24 IL6 24件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, TNF signaling pathway, Intestinal immune network for IgA production, Non-alcoholic fatty liver disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Malaria, Tuberculosis, Measles, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis, Lipid and atherosclerosis D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
25 IL6 24件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, TNF signaling pathway, Intestinal immune network for IgA production, Non-alcoholic fatty liver disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Malaria, Tuberculosis, Measles, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis, Lipid and atherosclerosis D09669 Siltuximab 2件: 28, 331
26 IL6 24件: Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, JAK-STAT signaling pathway, Th17 cell differentiation, TNF signaling pathway, Intestinal immune network for IgA production, Non-alcoholic fatty liver disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Pathogenic Escherichia coli infection, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Malaria, Tuberculosis, Measles, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Transcriptional misregulation in cancer, Rheumatoid arthritis, Lipid and atherosclerosis D10080 Sirukumab 2件: 41, 46
27 IL10 12件: Viral protein interaction with cytokine and cytokine receptor, JAK-STAT signaling pathway, T cell receptor signaling pathway, Intestinal immune network for IgA production, Pertussis, Yersinia infection, Leishmaniasis, Malaria, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Systemic lupus erythematosus D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
28 ITGA4 6件: PI3K-Akt signaling pathway, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis D06590 Firategrast 1件: 13
29 ITGA4 6件: PI3K-Akt signaling pathway, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis D06886 Natalizumab 6件: 13, 15, 25, 46, 63, 96
30 ITGA4 6件: PI3K-Akt signaling pathway, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis D08083 Vedolizumab 3件: 94, 96, 97
31 ITGA4 6件: PI3K-Akt signaling pathway, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Yersinia infection, Leishmaniasis D10540 Abrilumab 2件: 96, 97
32 ITGB7 4件: PI3K-Akt signaling pathway, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D08083 Vedolizumab 3件: 94, 96, 97
33 ITGB7 4件: PI3K-Akt signaling pathway, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D09901 Etrolizumab 2件: 96, 97
34 ITGB7 4件: PI3K-Akt signaling pathway, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer D10540 Abrilumab 2件: 96, 97
35 TNFRSF17 1件: Intestinal immune network for IgA production D11595 Belantamab mafodotin 1件: 28
36 TGFB1 16件: MAPK signaling pathway, TGF-beta signaling pathway, Osteoclast differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Relaxin signaling pathway, Non-alcoholic fatty liver disease, Leishmaniasis, Malaria, Toxoplasmosis, Tuberculosis, Pathways in cancer, Proteoglycans in cancer, Renal cell carcinoma, Pancreatic cancer, Rheumatoid arthritis D09620 Fresolimumab 4件: 51, 85, 222, 274
37 CXCR4 5件: Viral protein interaction with cytokine and cytokine receptor, Leukocyte transendothelial migration, Intestinal immune network for IgA production, Regulation of actin cytoskeleton, Pathways in cancer D08971 Plerixafor 6件: 19, 20, 51, 65, 285, 299
38 TNFSF13 2件: Intestinal immune network for IgA production, Rheumatoid arthritis D09704 Atacicept 4件: 13, 46, 49, 66
39 CD80 6件: Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
40 CD80 6件: Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D03222 Belatacept 1件: 46
41 CD86 8件: Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D03203 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
42 CD86 8件: Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Type I diabetes mellitus, Kaposi sarcoma-associated herpesvirus infection, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Rheumatoid arthritis, Viral myocarditis D03222 Belatacept 1件: 46
43 CD40 10件: NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis D11357 Bleselumab 1件: 222
44 CD40 10件: NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis D11597 Ravagalimab 2件: 53, 97
45 CD40 10件: NF-kappa B signaling pathway, Toll-like receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Transcriptional misregulation in cancer, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis D11610 Iscalimab 2件: 49, 53
46 CD40LG 9件: NF-kappa B signaling pathway, T cell receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Systemic lupus erythematosus, Primary immunodeficiency, Viral myocarditis, Lipid and atherosclerosis D06193 Toralizumab 1件: 63