Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Trendar Pms Caplet)		[5] Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Acetic acid
(Synonym: Treagan Otic)		[1] Acetic acid[1] D00010 --[1] 97
3 Adenosine
(Synonym: rootree Treetherapy NUTMEG TREE Facial Mask)		[2] Adenosine; Ginseng[1] D00045 [4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65
4 Alitretinoin
(Synonym: 9-cis-Tretinoin)		[2] ALITRETINOIN; Toctino[1] D02815 [5] RARA,
RARB,
RXRA,
RXRB,
RXRG 💬		[19] Acute myeloid leukemia, Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[1] 49
5 Allantoin
(Synonym: 3M Nexcare Cold Sore Treatment)		[1] ALLANTOIN[1] D00121 --[1] 36
6 Antihemophilic factor human
(Synonym: Profilate Heat Treated-wet Method Inj)		[6] Alphanate; Factor VIII; HUMAN COAGULATION FACTOR VIII; Humate-P; Voncento; WILATE---[1] 288
7 Bendamustine
(Synonym: Treanda)		[2] Bendamustine; BENDAMUSTINE HYDROCHLORIDE[1] D07501 (Name: Treanda (TN))--[2] 28, 61
8 Biotin
(Synonym: Bonogen Activator hair loss treatment)		[4] BIOTIN; Biotina; D-BIOTIN; Vitamin B7[1] D00029 --[5] 2, 8, 10, 13, 20
9 Butylene glycol
(Synonym: Buddate Reges Intensive Treatment)		[0] [1] D10695 --[2] 28, 46
10 Caffeine
(Synonym: Trezix)		[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 2, 6, 13, 21, 46, 78, 96, 97, 265
11 Calcium
(Synonym: Restoration Treatment)		[2] Calcio; Calcium---[30] 3, 6, 13, 15, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 256, 265, 274, 298, 299
12 Catridecacog
(Synonym: Tretten)		[1] Catridecacog[1] D10532 --[2] 97, 288
13 Chlorpheniramine
(Synonym: Anakit Insect Sting Treatment Kit)		[1] Clorfenamina[4] D00665 ,
D00668 ,
D07398 ,
D07803 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
14 Clindamycin
(Synonym: Clindamycin Phosphate and Tretinoin)		[2] CLINDAMYCIN; Dalacin C phosphate[4] D00277 ,
D01073 ,
D01990 ,
D02132 		--[2] 46, 299
15 Clotrimazole
(Synonym: Terrasil Anti-Fungal Treatment MAX)		[1] Clotrimazole[1] D00282 --[1] 97
16 Dihydrocodeine
(Synonym: Trezix)		[0] [2] D01481 ,
D07831 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 310
17 Epinephrine
(Synonym: Anakit Insect Sting Treatment Kit)		[3] Epinephrine; Lidocaine; Xylocaine[3] D00095 ,
D00996 ,
D02149 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 46, 70, 96
18 Esomeprazole
(Synonym: Berkley and Jensen Heartburn Treatment)		[3] Esomeprazole; Nexium; Omeprazole[4] D01984 ,
D04056 ,
D07917 ,
D09339 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299
19 Ethanol
(Synonym: Anti-Bacterial Hand Pear Tree)		[3] Alcohol; Ethanol; PREDNISONE[4] D00068 ,
D02798 ,
D04855 ,
D06542 		--[7] 13, 51, 58, 97, 279, 280, 298
20 Ginkgo biloba
(Synonym: Maidenhair tree leaf)		[3] Ginkgo; Ginkgo biloba; Tanakan---[5] 6, 13, 18, 47, 90
21 Glycerin
(Synonym: Tea Tree Ampoule)		[3] Bee venom; Glycerine; Glycerol[1] D00028 --[6] 6, 13, 79, 265, 316, 317
22 Glycine
(Synonym: CAREDO Treating Gingivitis Toothpastes 100g)		[1] Glycine[1] D00011 --[5] 35, 60, 86, 226, 299
23 Guselkumab
(Synonym: Tremfya)		[2] GUSELKUMAB; Tremfya[1] D10438 (Name: Tremfya (TN))[1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[5] 37, 41, 51, 96, 97
24 Histidine
(Synonym: Trepoxen-250)		[2] Histidine; L-Histidine[1] D00032 --[3] 13, 169, 170
25 Horse chestnut [1] Horse chestnut[1] D12028 (Name: Conker tree)--[1] 210
26 Hydrocortisone
(Synonym: Post Treatment Balm)		[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[11] 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
27 Hydrocortisone acetate
(Synonym: Irritated Skin Treatment)		[2] Hydrocortisone; HYDROCORTISONE ACETATE[1] D00165 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
28 Lansoprazole
(Synonym: Rugby Heartburn Treatment)		[1] Lansoprazole[1] D00355 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[7] 63, 71, 85, 98, 166, 222, 299
29 Lidocaine
(Synonym: Family Medic First-aid Treatment Liquid)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[3] D00358 ,
D02086 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
30 Methotrexate
(Synonym: Trexall)		[6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate[2] D00142 ,
D02115 (Name: Trexall (TN))		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
31 Minoxidil
(Synonym: MDhair Extra Strength hair regrowth treatment for Men)		[1] MINOXIDIL[1] D00418 [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[1] 179
32 Naproxen
(Synonym: Trepoxen-250)		[5] Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[1] D00118 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271
33 Nicotinamide
(Synonym: Seanol Facial Treatment Mask)		[4] Ginseng; Multivitamin; Niacinamide; Nicotinamide[1] D00036 --[11] 2, 5, 6, 13, 18, 49, 65, 67, 107, 162, 191
34 Olive oil
(Synonym: Intensive Treatment Bodyoil for Mommy To Be All Skin)		[1] Olive Oil[1] D03311 --[3] 13, 49, 53
35 Pentoxifylline
(Synonym: Trental Tab 400mg)		[1] Pentoxifylline[1] D00501 (Name: Trental (TN))--[10] 26, 56, 84, 93, 96, 113, 220, 222, 296, 298
36 Petrolatum
(Synonym: Shopko Lip Treatment)		[1] Petrolatum[1] D05331 --[3] 35, 158, 162
37 Phenylephrine
(Synonym: Trexbrom)		[1] Phenylephrine[2] D00511 ,
D08365 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
38 Salicylic acid
(Synonym: Botanic Skincare Acne Defense Treatment)		[2] 2-Hydroxybenzoic acid; Salicylic acid[1] D00097 --[1] 97
39 Sodium fluoride
(Synonym: SheerFluorX Fluoride Treatment)		[2] Beam; Sodium fluoride[1] D00943 --[1] 51
40 Threonine
(Synonym: Treonina)		[1] Threonine[1] D00041 --[3] 86, 96, 97
41 Thymol
(Synonym: Acne Vanish Synergy for treatment of Acnes)		[1] Thymol[1] D01039 --[1] 13
42 Tregalizumab [1] Tregalizumab---[1] 46
43 Trehalose [2] Cabaletta; Trehalose---[3] 2, 18, 113
44 Tremelimumab [1] Ticilimumab[1] D06657 (Name: Tremelimumab)[1] CTLA4 💬[4] Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬[1] 96
45 Treosulfan [2] OVASTAT; TREOSULFAN[1] D07253 (Name: Treosulfan)--[6] 13, 19, 62, 65, 283, 286
46 Treprostinil [4] Remodulin; Treprostinil; Treprostinilo; Tyvaso[1] D06213 (Name: Treprostinil)[1] PTGIR 💬[3] Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬[6] 51, 84, 85, 86, 88, 210
47 Tretinoin [5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID[1] D00094 (Name: Tretinoin)[3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231
48 Triamcinolone
(Synonym: Treziopak)		[4] Kenalog; Naltrexone; Triamcinolone; Triamcinolone Acetonide[5] D00385 ,
D00983 ,
D00984 ,
D00985 ,
D06216 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 35, 46, 56, 70, 90, 96, 107, 162, 226, 298
49 Triptorelin
(Synonym: Trelstar)		[2] GnRH; Triptorelin[1] D06247 [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[2] 49, 76