Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Tryptophan 💬 1件: Tryptophan2件: Propanoic acid; Tryptophan; --1件: 6 💬
2 Phenylalanine 💬 1件: Phenylalanine1件: Phenylalanine; --1件: 240 💬
3 Tyrosine 💬 1件: Tyrosine4件: Alanine; L-Tyrosine; Propanoic acid; Tyrosine; --4件: 6, 86, 111, 298 💬
4 Hydrocortisone 💬 1件: Hydrocortisone6件: Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
5 Tretinoin 💬 1件: Tretinoin5件: ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID; 3件: PML,
RARA,
RARB 💬		12件: Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬6件: 2, 62, 63, 75, 94, 231 💬
6 Corticotropin 💬 1件: Corticotropin5件: ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin; 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬12件: 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
7 Alprazolam 💬 1件: Alprazolam1件: Alprazolam; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 8, 75 💬
8 Desmopressin 💬 1件: Desmopressin5件: DDAVP; Desmopressin; Desmopressin acetate; Desmopressine; Minirin; 2件: AVPR2,
F8 💬		4件: Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬6件: 6, 64, 72, 75, 225, 288 💬
9 Ketoconazole 💬 1件: Ketoconazole2件: KETOCONAZOLE; NIZORAL; 1件: CYP17A1 💬6件: Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬3件: 8, 13, 75 💬
10 Valsartan 💬 1件: Valsartan3件: Diovan; Entresto; Valsartan; 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬7件: 57, 58, 66, 75, 218, 222, 224 💬
11 Metyrapone 💬 1件: Metyrapone2件: Metopirone; METYRAPONE; 1件: CYP11B1 💬4件: Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Steroid hormone biosynthesis 💬1件: 75 💬
12 Octreotide 💬 1件: Octreotide3件: Octreotide; OCTREOTIDE ACETATE; Sandostatin LAR; 1件: SSTR2 💬4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬7件: 67, 75, 84, 85, 89, 193, 227 💬
13 Prednisolone 💬 1件: Prednisolone3件: Prednisolona; Prednisolone; Prednisolonum; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬42件: 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
14 Propofol 💬 1件: Propofol2件: Propofol; Propofol Injection; 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬8件: 6, 21, 22, 34, 46, 70, 98, 296 💬
15 Mifepristone 💬 1件: Mifepristone1件: MIFEPRISTONE; 2件: NR3C1,
PGR 💬		6件: Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Neuroactive ligand-receptor interaction, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬1件: 75 💬
16 Calcium carbonate 💬 1件: Calcium carbonate3件: Calcio carbonato; Calcium; Calcium Carbonate; --9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
17 Cabergoline 💬 1件: Cabergoline3件: CABERGOLINA; Cabergoline; DOSTINEX; 2件: DRD2,
PRL 💬		12件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 74, 75 💬
18 Eplerenone 💬 1件: Eplerenone1件: Eplerenone; 1件: NR3C2 💬1件: Aldosterone-regulated sodium reabsorption 💬4件: 75, 113, 210, 215 💬
19 Pentetreotide 💬 1件: Pentetreotide1件: Pentetreotide; --1件: 75 💬
20 Gefitinib 💬 1件: Gefitinib1件: Gefitinib; 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 75 💬
21 Tadalafil 💬 1件: Tadalafil4件: Adcirca; CIALIS; TADALAFIL; TADALAFILO; 1件: PDE5A 💬3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 84, 86, 113, 210 💬
22 Bexarotene 💬 1件: Bexarotene2件: Bexarotene; Targretin; 3件: RXRA,
RXRB,
RXRG 💬		17件: Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬2件: 13, 75 💬
23 Corticorelin ovine triflutate 💬 1件: Corticorelin ovine triflutate1件: Acthrel; 2件: CRHR1,
CRHR2 💬		4件: Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 75 💬
24 Corticorelin 💬 1件: Corticorelin1件: Corticotropin-releasing hormone; 2件: CRHR1,
CRHR2 💬		4件: Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 75 💬
25 Metformin 💬 1件: Metformin5件: METFORMIN; Metformin HCl; Metformin hydrochloride; METFORMINA; Metformine; 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬25件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
26 Vorinostat 💬 1件: Vorinostat1件: Vorinostat; 11件: HDAC1,
HDAC10,
HDAC11,
HDAC2,
HDAC3,
HDAC4,
HDAC5,
HDAC6,
HDAC7,
HDAC8,
HDAC9 💬		17件: Alcoholism, Amphetamine addiction, Amyotrophic lateral sclerosis, Apelin signaling pathway, Cell cycle, Chronic myeloid leukemia, Epstein-Barr virus infection, Human papillomavirus infection, Huntington disease, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, Notch signaling pathway, Pathways in cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis 💬2件: 75, 96 💬
27 Liraglutide 💬 1件: Liraglutide2件: LIRAGLUTIDE; Saxenda; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 6, 75, 193 💬
28 Dabigatran etexilate 💬 1件: Dabigatran etexilate1件: Dabigatran Etexilate; 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬2件: 51, 75 💬
29 Lapatinib 💬 1件: Lapatinib1件: Lapatinib; 2件: EGFR,
ERBB2 💬		50件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Platinum drug resistance, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Tight junction 💬3件: 34, 74, 75 💬
30 Rosiglitazone 💬 1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate; 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬5件: 46, 75, 97, 222, 265 💬
31 Sitagliptin 💬 1件: Sitagliptin1件: Sitagliptin; 1件: DPP4 💬1件: Protein digestion and absorption 💬4件: 6, 75, 233, 299 💬
32 Dabigatran 💬 1件: Dabigatran1件: Dabigatran; 1件: F2 💬8件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬5件: 51, 75, 85, 91, 124 💬
33 Pasireotide 💬 1件: Pasireotide3件: Pasireotida; Pasireotide; SIGNIFOR; 4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬		4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 67, 74, 75 💬
34 Calcium carbonate 💬 1件: Calcium carbonate3件: Calcio carbonato; Calcium; Calcium carbonate; --9件: 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
35 Levoketoconazole 💬 1件: Levoketoconazole1件: Levoketoconazole; 3件: CYP11A1,
CYP11B1,
CYP17A1 💬		7件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬1件: 75 💬
36 Osilodrostat 💬 1件: Osilodrostat1件: OSILODROSTAT; 1件: CYP11B2 💬3件: Aldosterone synthesis and secretion, Metabolic pathways, Steroid hormone biosynthesis 💬1件: 75 💬
37 Nevanimibe 💬 1件: Nevanimibe1件: Nevanimibe; --2件: 75, 81 💬
38 Relacorilant 💬 1件: Relacorilant2件: CORT125134; Relacorilant; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 75 💬