Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Adherens junction 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
2 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
3 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
LEPR 1件: LEPR 💬 |
Metreleptin Metreleptin 💬 |
Metreleptin | 265 1件: 265 💬 💬 |
4 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
5 | Adipocytokine signaling pathway 💬 16 genes, 31 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
6 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
7 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
8 | Alcoholic liver disease 💬 39 genes, 46 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
9 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
10 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
11 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
12 | Aldosterone synthesis and secretion 💬 20 genes, 38 drugs (DrugBank) and 62 diseases |
PDE2A 1件: PDE2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
13 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
14 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬 |
Pravastatin Pravastatin 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬 |
15 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
HMGCR 1件: HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
16 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
17 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
LEPR 1件: LEPR 💬 |
Metreleptin Metreleptin 💬 |
Metreleptin | 265 1件: 265 💬 💬 |
18 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
19 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
20 | AMPK signaling pathway 💬 16 genes, 49 drugs (DrugBank) and 93 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
21 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
22 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
23 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
24 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
25 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
26 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
27 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬 |
Pravastatin Pravastatin 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬 |
28 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
HMGCR 1件: HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
29 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
NR1H4 1件: NR1H4 💬 |
Cholic acid Cholic acid 💬 |
Cholic Acid | 020 4件: 20, 234, 265, 310 💬 💬 |
30 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 60 diseases |
NR1H4 1件: NR1H4 💬 |
Obeticholic acid Obeticholic acid 💬 |
Obeticholic acid | 093 3件: 93, 265, 296 💬 💬 |
31 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
32 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A 2件: ADORA2A, PDE1B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
33 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
ADORA2A 2件: ADORA2A, PDE1B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
34 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
35 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
36 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
37 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
38 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
39 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
40 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
41 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
42 | Cholesterol metabolism 💬 6 genes, 8 drugs (DrugBank) and 6 diseases |
APOC3 1件: APOC3 💬 |
Volanesorsen Volanesorsen 💬 |
Volanesorsen | 265 1件: 265 💬 💬 |
43 | Cholinergic synapse 💬 32 genes, 48 drugs (DrugBank) and 59 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
44 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 25 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
45 | Coronavirus disease - COVID-19 💬 51 genes, 94 drugs (DrugBank) and 91 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
46 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR 1件: GHR 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
47 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
GHR 1件: GHR 💬 |
Pegvisomant Pegvisomant 💬 |
Pegvisomant | 078 2件: 78, 265 💬 💬 |
48 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
LEPR 1件: LEPR 💬 |
Metreleptin Metreleptin 💬 |
Metreleptin | 265 1件: 265 💬 💬 |
49 | Diabetic cardiomyopathy 💬 26 genes, 42 drugs (DrugBank) and 73 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
50 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
51 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
52 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
53 | Endocytosis 💬 15 genes, 28 drugs (DrugBank) and 51 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
54 | Epstein-Barr virus infection 💬 44 genes, 62 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
55 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
56 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
57 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
58 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
59 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
60 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
61 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
62 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
63 | Glucagon signaling pathway 💬 12 genes, 19 drugs (DrugBank) and 83 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
64 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
GHR 1件: GHR 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
65 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
GHR 1件: GHR 💬 |
Pegvisomant Pegvisomant 💬 |
Pegvisomant | 078 2件: 78, 265 💬 💬 |
66 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
GHRHR 1件: GHRHR 💬 |
Tesamorelin Tesamorelin 💬 |
Tesamorelin | 078 2件: 78, 265 💬 💬 |
67 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
68 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
69 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
70 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
71 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
72 | Herpes simplex virus 1 infection 💬 43 genes, 65 drugs (DrugBank) and 94 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
73 | HIF-1 signaling pathway 💬 23 genes, 48 drugs (DrugBank) and 76 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
74 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
75 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
76 | Human T-cell leukemia virus 1 infection 💬 37 genes, 59 drugs (DrugBank) and 84 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
77 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
78 | Huntington disease 💬 24 genes, 33 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
79 | Hypertrophic cardiomyopathy 💬 20 genes, 51 drugs (DrugBank) and 87 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
80 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
81 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
82 | Insulin resistance 💬 18 genes, 33 drugs (DrugBank) and 95 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
83 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
84 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
85 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
86 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
GHR 1件: GHR 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
87 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
GHR 1件: GHR 💬 |
Pegvisomant Pegvisomant 💬 |
Pegvisomant | 078 2件: 78, 265 💬 💬 |
88 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
89 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
LEPR 1件: LEPR 💬 |
Metreleptin Metreleptin 💬 |
Metreleptin | 265 1件: 265 💬 💬 |
90 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
91 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
92 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
93 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
94 | Lipid and atherosclerosis 💬 46 genes, 56 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
95 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
96 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
97 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
98 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
99 | Longevity regulating pathway 💬 11 genes, 20 drugs (DrugBank) and 68 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
100 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
101 | Longevity regulating pathway - multiple species 💬 11 genes, 15 drugs (DrugBank) and 62 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
102 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
103 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
104 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
105 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
106 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬 |
Pravastatin Pravastatin 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬 |
107 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
HMGCR 1件: HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
108 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
109 | Metabolic pathways 💬 111 genes, 155 drugs (DrugBank) and 137 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
110 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
111 | Morphine addiction 💬 41 genes, 65 drugs (DrugBank) and 73 diseases |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
112 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
113 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
114 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
115 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 2件: ADORA1, ADORA2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
116 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
ADORA1 2件: ADORA1, ADORA2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
117 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR 1件: GHR 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
118 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHR 1件: GHR 💬 |
Pegvisomant Pegvisomant 💬 |
Pegvisomant | 078 2件: 78, 265 💬 💬 |
119 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
GHRHR 1件: GHRHR 💬 |
Tesamorelin Tesamorelin 💬 |
Tesamorelin | 078 2件: 78, 265 💬 💬 |
120 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
LEPR 1件: LEPR 💬 |
Metreleptin Metreleptin 💬 |
Metreleptin | 265 1件: 265 💬 💬 |
121 | Neuroactive ligand-receptor interaction 💬 149 genes, 320 drugs (DrugBank) and 153 diseases |
MC4R 1件: MC4R 💬 |
Setmelanotide Setmelanotide 💬 |
Setmelanotide | 202 2件: 202, 265 💬 💬 |
122 | NOD-like receptor signaling pathway 💬 30 genes, 42 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
123 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
LEPR 1件: LEPR 💬 |
Metreleptin Metreleptin 💬 |
Metreleptin | 265 1件: 265 💬 💬 |
124 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
125 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
126 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
127 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
128 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1B 2件: PDE1B, PDE2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
129 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1B 2件: PDE1B, PDE2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
130 | Oocyte meiosis 💬 14 genes, 41 drugs (DrugBank) and 77 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
131 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
132 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
133 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
134 | Ovarian steroidogenesis 💬 7 genes, 36 drugs (DrugBank) and 52 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
135 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
136 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
137 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
138 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
139 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
140 | Parkinson disease 💬 24 genes, 73 drugs (DrugBank) and 66 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
141 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
142 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
143 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
144 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
145 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
146 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR 1件: GHR 💬 |
Pegvisomant Pegvisomant 💬 |
Pegvisomant | 078 2件: 78, 265 💬 💬 |
147 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
GHR 2件: GHR, IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
148 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
149 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
150 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
APOC3 1件: APOC3 💬 |
Volanesorsen Volanesorsen 💬 |
Volanesorsen | 265 1件: 265 💬 💬 |
151 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARA 1件: PPARA 💬 |
Fenofibrate Fenofibrate 💬 |
Fenofibrate | 008 6件: 8 , 79, 93, 94, 97, 265 💬 💬 |
152 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
153 | PPAR signaling pathway 💬 10 genes, 14 drugs (DrugBank) and 32 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
154 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
155 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
156 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
PDE3B 1件: PDE3B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
157 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
JAK2 1件: JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
158 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
159 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
160 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
161 | Purine metabolism 💬 29 genes, 35 drugs (DrugBank) and 73 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
162 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
163 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
164 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
165 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
166 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADORA1 2件: ADORA1, PDE3B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
167 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 69 diseases |
ADORA1 2件: ADORA1, PDE3B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
168 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
169 | Renin secretion 💬 28 genes, 82 drugs (DrugBank) and 107 diseases |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
170 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
171 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
172 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 1件: ADORA1 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
173 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
ADORA1 1件: ADORA1 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
174 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1B 1件: PDE1B 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
175 | Taste transduction 💬 30 genes, 81 drugs (DrugBank) and 65 diseases |
PDE1B 1件: PDE1B 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
176 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬 |
Atorvastatin Atorvastatin 💬 |
Atorvastatin | 013 19件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬 💬 |
177 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬 |
Pravastatin Pravastatin 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 💬 |
178 | Terpenoid backbone biosynthesis 💬 4 genes, 12 drugs (DrugBank) and 53 diseases |
HMGCR 1件: HMGCR 💬 |
Simvastatin Simvastatin 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 💬 |
179 | Th1 and Th2 cell differentiation 💬 33 genes, 37 drugs (DrugBank) and 70 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
180 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
181 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
182 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
183 | Thermogenesis 💬 17 genes, 29 drugs (DrugBank) and 82 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
184 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
185 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
186 | Tight junction 💬 11 genes, 29 drugs (DrugBank) and 45 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
Metformin Metformin 💬 |
Metformin | 002 25件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬 💬 |
187 | Toxoplasmosis 💬 25 genes, 39 drugs (DrugBank) and 64 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
188 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
IGF1R 1件: IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 💬 |
189 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
PPARG 1件: PPARG 💬 |
Pioglitazone Pioglitazone 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬 |
190 | Transcriptional misregulation in cancer 💬 26 genes, 49 drugs (DrugBank) and 76 diseases |
PPARG 1件: PPARG 💬 |
Rosiglitazone Rosiglitazone 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 💬 |
191 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
JAK1 2件: JAK1, JAK2 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |
192 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine Caffeine 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
193 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
ADORA2A 1件: ADORA2A 💬 |
Caffeine hydrate Caffeine hydrate 💬 |
Caffeine | 002 8件: 2 , 6 , 21, 46, 78, 96, 97, 265 💬 💬 |
194 | Viral carcinogenesis 💬 25 genes, 23 drugs (DrugBank) and 40 diseases |
JAK1 1件: JAK1 💬 |
Baricitinib Baricitinib 💬 |
Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬 💬 |